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Man United vs. Chelsea prediction, odds, betting tips and best bets for Premier League match

Kyle Bonn

Man United vs. Chelsea prediction, odds, betting tips and best bets for Premier League match image

Two Premier League giants meet hoping to keep a poor result from becoming a poor run of form as Chelsea travel north to visit Manchester United on Sunday.

The Blues fell 3-1 on the road at Bayern Munich on Wednesday to open their Champions League slate. They put up a good fight in the opening 45 minutes and were unlucky to find themselves down a goal at halftime, but Enzo Maresca's team were well beaten by the end of the game.

 

That, coupled with just two wins in their first four Premier League games, has left the head coach with a spotty start to the new campaign to sort through.

United, meanwhile, were humbled by their derby rivals Manchester City last weekend, falling 3-0 in a game in which the Red Devils were a clear second-best despite having more possession and more shots. It left them with just one win from their first four Premier League games, alongside two defeats and a draw, with Ruben Amorim feeling the heat already.

As such, both sides will be motivated to turn around their recent struggles, while any potential loser would find themselves searching for answers amidst a poor start to the campaign.

MORE: Predicted lineups, team news, and latest injury updates ahead of Man United vs. Chelsea

Man United vs. Chelsea prediction, odds

Chelsea may have been humbled by Bayern Munich midweek, but the Blues are far and away the better side between these two and should be poised for a comeback.

United have been poor so far this season, even against weaker sides, and the one game they looked competent in still resulted in defeat to Arsenal to begin the season. Their finishing has been extremely poor, and the absence of Matheus Cunha due to injury has left a hole in their already sputtering attack.

Chelsea have not beaten Man United in Premier League action at Old Trafford since 2013, but they have won two of the last three meetings between these sides. If Maresca allows Cole Palmer to play through the middle where he's at his best, and turns to the new signings for wide creative play, the Blues should manage to ease their way to three points.

 DraftKings
(USA)
Man United win+165
Draw+265
Chelsea win+155
Both teams
to score
Y: -220
N: +170
Over / Under
2.5 goals
O: -180
U: +140
Chelsea
-0.5 goals
+140
Man United
+0.5 goals
-200

Man United vs. Chelsea match facts

  • Date: Saturday, September 20, 2025
  • Kickoff Time: 5:30 p.m. local (12:30 p.m. ET / 9:30 a.m. PT)
  • Location: Old Trafford (Manchester, England)
  • Referee: Peter Bankes, VAR: Craig Pawson
  • Last meeting: Chelsea 1-0 Man United (May 16, 2025 | Premier League)

MORE: A complete guide to betting on soccer in the United States

Man United vs. Chelsea best bet

Nobody in the Premier League performs in the biggest games like Palmer, who once again dazzled as he did his best to carry a sputtering Chelsea in Bavaria on Wednesday. On his Champions League debut for the club, Palmer scored a goal and nearly had another, chalked off by VAR for a tight offside decision.

Palmer has nine shot-creating actions in just 124 minutes of Premier League play this season, a per-90 clip of 6.48, which ranks him second only behind Bruno Fernandes who leads the league in the category with 31.

The 23-year-old has not picked up a goal contribution against United in two games, but he will recall the hat-trick he bagged in April of 2024 that saw Chelsea win a 4-3 thriller at home.

Man Untied vs. Chelsea prop bet

  • Pick: Over 4.5 yellow cards
  • Odds: -115 on FanDuel

This fixture is often a pressure cooker, as these two teams have racked up 22 yellow cards across the last four meetings.

While the two sides rank in the bottom half of the Premier League in fouls so far this season, referee Peter Bankes is not afraid to let the bookings fly. He has averaged exactly 4.5 yellow cards per match through his first four assignments of the season, and two of his last three matches officiating Manchester United have seen six yellow cards shown.

With both sides increasingly desperate for points given the narrative of their seasons so far, there will be extra pressure on the result of this match, and an increased likelihood of emotions boiling over.

Kyle Bonn

Kyle Bonn is a Syracuse University broadcast journalism graduate with over a decade of experience covering soccer globally. Kyle specializes in soccer tactics and betting, with a degree in data analytics. Kyle also does TV broadcasts for Wake Forest soccer, and has had previous stops with NBC Soccer and IMG College. When not covering the game, he has long enjoyed loyalty to the New York Giants, Yankees, and Fulham. Kyle enjoys playing racquetball and video games when not watching or covering sports.