There were many offensive changes around the NFL ahead of the 2025 season, both in terms of personnel scheme.
That's led to revving up some new passing game combinations with quarterbacks and fresh go-to guys.
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Week 1 delivered some breakout dynamic duos who should be key for their teams going forward. They also were good setups for fantasy football scoring promise for the rest of the season.
MORE NFL WEEK 1
- The best from Travis Hunter's NFL debut vs. Panthers
- How turnovers impacted Tua Tagovailoa's ugly season-opening showing
- Aaron Rodgers gets revenge on former team as Steelers best Jets
Here's breaking down the most fun of the breakout 1-2 punches:
NFL's 6 best new quarterback-wide receiver duos

Justin Fields and Garrett Wilson, Jets
The wild shootout with the Pittsburgh Steelers, a heartbreaking 34-32 loss, still should have been an inspiring result for Jets fans. The Steelers won and Aaron Rodgers got his winning revenge at MetLife Stadium. Fields played well against his former team's tough defense to think the Jets will field a much better offense.
But it was also a sneaky revenge game for Wilson. Wilson's rapport with Rodgers never materialized, a big reason for the Jets' offensive dysfunction with a healthy Rodgers in 2024. Wilson had extra pep in his step with Rodgers and Jalen Ramsey on the other side, with 7 catches for 95 yards on a healthy 9 targets from Fields. All other Jets' wideouts combined for 5 targets.
Wilson is getting treated like the No. 1 he should be. Fields is smart to butter his bread with Wilson in the Lions-like offense under coordinator Tanner Engstrand.
MORE: Grading NFL Week 1 debuts, from Aaron Rodgers and Travis Hunter to Justin Fields

Baker Mayfield and Emeka Egbuka, Buccaneers
The rookie first-rounder Egbuka starring right away was much expected away from Mike Evans vs. the Falcons' weak secondary away from A.J. Terrell. With Chris Godwin and Jalen McMillan on the shelf, Egbuka figured to be busy in his debut. Egbuka turned his six targets into 67 yards and two TDs, including the game-winning strike down the middle late from Mayfield.
Egbuka isn't just a fill-in for Godwin and McMillan in the short term. He is set up to become the No. 1 when Evans, 32, reaches the imminent end. Egbuka saved the Bucs big-time in their 23-20 win over the Falcons and will continue to see high-leverage clutch targets.
Geno Smith and Jakobi Meyers, Raiders
Smith threw a ton to Jaxson Smith-Njigba, who often lined up in the slot, in Seattle. Smith is treating Meyers the same way on his new team, playing off elite second-year receiving tight end Brock Bowers. With Bowers hurting his knee, Meyers might see a much bigger role after his eight catches for 97 yards on 10 targets were key in taking down his former team, the Patriots, 20-13 in another Week 1 revenge game.
Smith has cleaned up the Raiders' QB mess in a hurry in Chip Kelly's offense in his reunion with Pete Carroll. He's back to executing well in a system tailored to his strengths.
MORE: Will Dolphins fire Mike McDaniel after poor Week 1 showing?

Aaron Rodgers and DK Metcalf, Steelers
Rodgers and Metcalf didn't go nuts a la Wilson and Fields on the other side. Metcalf played like his usual self from Seattle, catching four of 7 targets for 83 yards. He made some big plays; he also missed a couple. Although Rodgers was on fire spreading the ball around with four passing TDs to four non-Metcalf targets, DK's presence downfield opened up a lot. As an aside, Rodgers seems already in the zone in Arthur Smith's Steelers offense, something he never felt with Nathaniel Hackett and the Jets.
Jayden Daniels and Deebo Samuel Jr., Commanders
Daniels had to be relieved Terry McLaurin ended his contract drama right before the season. But McLaurin (2 catches, 27 yards) had his expected rusty game in Week 1 vs. the Giants. Samuel, however, was locked into his new QB coming over from the 49ers, with a Commanders-high seven catches for 77 yards on a busy 10 targets. Daniels officially has the ideal upgrade for his No. 2 and Samuel can often operate like a No. 1 in Kliff Kingsbury's offense.
MORE: How missed field goal by Browns kicker Andre Szmyt cost Cleveland win
Daniel Jones and Michael Pittman Jr., Colts
Jones made his case to keep Anthony Richardson on the bench with his stellar first performance for Indianapolis (22-for-29, 279 passing yards, TD, 7 rushes, 26 yards, 2 TDs). The big reason Shane Steichen stuck with Jones over Richardson was his ability to handle the intermediate passing game, key for a team with Pittman and rookie tight end Tyler Warren as its best receivers.
Pittman went back to his pre-Richardson type of production with six catches for 80 yards and a TD on 8 targets. Warren was right behind with 7 catches for 76 yards on nine targets. The Dolphins had no answers in coverage for either underneath target. Jones knew what he had to do to win and move the ball well in a favorable matchup at home. Pittman and Warren will be remain huge in the game plans.