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NFL Week 7 betting odds, lines, point spreads and over/under totals for every 2024 football game

Sloan Piva

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With one-third of the 2024 regular season in the books, things have really started to heat up in the NFL. And with 14 games lined up this week, bettors will be looking forward to a fully-loaded Week 7 slate. 

The most important part of betting is not luck — it's knowledge. Checking this column early and often each week helps you identify value wagers, recognize betting trends, and understand how oddsmakers think.

Then, when the betting public influences shifts in the odds throughout the week, you start realizing the angles worth attacking. Paired with SN's best bets, primetime game predictions, and weekly pick'em columns, you'll have all the resources you need to be a confident and informed bettor.

Long story short, this column will host the moneyline, spread, and over/under odds for every matchup on the Week 7 schedule. Let's dive in, then break down the early values, top storylines, and props to target from the weekend's games. 

NFL Week 7 odds: Lines, spreads, over/under totals

All odds courtesy of BetMGM. 

Day/time (ET)	Game	ML	ATS	O/U
Thu., 10/17 8:15 p.m.	Broncos @ Saints	NO -115 DEN -105	NO -1 (+100) DEN +1 (-120)	O 36.5 (-110) U 36.5 (-110)
Sun., 10/20 9:30 a.m.	Patriots vs. Jaguars (N)	JAX -210 NE +175	JAX -5.5 (-110) NE +5.5 (-110)	O 41.5 (-110) U 41.5 (-110)
Sun., 10/20 1:00 p.m.	Seahawks @ Falcons	ATL -160 SEA +135	ATL -3 (-110) SEA +3 (-110)	O 48.5 (-110) U 48.5 (-110)
Sun., 10/20 1:00 p.m.	Titans @  Bills	BUF -450 TEN +350	BUF -9 (-110) TEN +9 (-110)	O 42.5 (-110) U 42.5 (-110)
Sun., 10/20 1:00 p.m.	Bengals @ Browns	CIN -225 CLE +185	CIN -4.5 (-115) CLE +4.5 (-105)	O 44.5 (-110) U 44.5 (-110)
Sun., 10/20 1:00 p.m.	Texans @  Packers	GB -140 HOU +115	GB -2.5 (-110) HOU +2.5 (-110)	O 46.5 (-115) U 46.5 (-105)
Sun., 10/20 1:00 p.m.	Dolphins @ Colts	IND -200 MIA +165	IND -4 (-110) MIA +4 (-110)	O 42.5 (-110) U 42.5 (-110)
Sun., 10/20 1:00 p.m.	Lions @ Vikings	MIN -120 DET +100	MIN -1.5 (-110) DET +1.5 (-110)	O 51.5 (-110) U 51.5 (-110)
Sun., 10/20 1:00 p.m.	Eagles @ Giants	PHI -210 NYG +170	PHI -4 (-110) NYG +4 (-110)	O 45.5 (-110) U 45.5 (-110)
Sun., 10/20 4:05 p.m.	Raiders @ Rams	LAR -225 LV +190	LAR -5.5 (-110) LV +5.5 (-110)	O 44 (-110) U 44 (-110)
Sun., 10/20 4:05 p.m.	Panthers @ Commanders	WAS -400 CAR +310	WAS -8.5 (-110) CAR +8.5 (-110)	O 51.5 (-110) U 51.5 (-110)
Sun., 10/20 4:25 p.m.	Chiefs @ 49ers	SF -115 KC -105	SF -1.5 (-105) KC +1.5 (-115)	O 48.5 (-110) U 48.5 (-110)
Sun., 10/20 8:20 p.m.	Jets @ Steelers	PIT -120 NYJ +100	PIT -1.5 (-110) NYJ +1.5 (-110)	O 37 (-110) U 37 (-110)
Mon., 10/21 8:15 p.m.	Ravens @ Buccaneers	BAL -210 TB +170	BAL -4 (-110) TB +4 (-110)	O 49.5 (-115) U 49.5 (-105)
Mon., 10/21 9:00 p.m.	Chargers @ Cardinals	LAC -135 ARI +115	LAC -2.5 (-110) ARI +2.5 (-110)	O 43.5 (-110) U 43.5 (-110)

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NFL Week 7: Odds, betting storylines to watch

Week 7 kicks off with a defensive battle in New Orleans, as the Saints host Bo Nix and the Broncos on Thursday Night Football. Then the Patriots hand the ball to Drake Maye for the rookie's second start, this time in London against the Jaguars. Betting against rookie QBs away from home seems like a sage decision.

Sunday's main slate features seven 1:00 p.m. games and four in the 4:00 p.m. window. The early highlights: a bird-brawl between the Seahawks and Falcons in the ATL, Jordan Love's Packers vs. C.J. Stroud's Texans in Green Bay, and Lions-Vikings in Minnesota. The Pack 2.5 at home feels like the best early value. 

The most anticipated game of the weekend, of course, is Chiefs at 49ers. A rematch of February's Super Bowl, this Santa Clara clash should draw crazy numbers both on the television market and on the betting markets. The opening lines revealed Kansas City as a slight underdog, but that could change quickly. 

A jam-packed week concludes with a doubleheader on Monday night. The first game will feature reigning MVP Lamar Jackson and the Ravens taking on emerging MVP candidate Baker Mayfield and the Buccaneers in Tampa, and the second game will feature Jim Harbaugh's Chargers visiting Kyler Murray, Marvin Harrison Jr. and the Cardinals.

The Bucs getting four points at opening tells us that oddsmakers and bettors alike remain defiant when it comes to this squad's status as a contender. The Chargers being listed as favorites over a feisty Cards team also feels like too much respect for Harbaugh and too little respect for Murray, MHJ and company.