Louisville welcomes James Madison to L&N Stadium on Friday night for a Week 2 primetime showdown.
The Cardinals opened their season in emphatic fashion, rolling past Eastern Kentucky 51-17 after building a commanding first-half lead. Still, Jeff Brohm’s group showed room for refinement, particularly with discipline, after being flagged 13 times in the win.
James Madison, meanwhile, wasted no time making a statement of its own, routing Weber State 45-10. Quarterback Alonza Barnett III accounted for two scores, one through the air and one on the ground, while tailbacks George Pettaway and Wayne Knight gashed the defense for 188 combined rushing yards.
The Dukes’ defense was just as ruthless, forcing three interceptions and disrupting six more passes to set the tone for their campaign.
Here's what you need to know to watch Louisville host James Madison on Friday, including start time and TV channel.
What channel is Louisville vs. James Madison on today?
- TV channel: ESPN2
- Live stream: Fubo
Louisville vs. James Madison will air live on ESPN2 with Jody Demling (play-by-play) and Michael McCammon (analyst) on the call.
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Louisville vs. James Madison start time
- Date: Friday, Sept. 5
- Kickoff: 7 p.m. ET
Louisville vs. James Madison is set to kick off at 7 p.m. ET from L&N Federal Credit Union Stadium in Louisville, Kentucky.
Louisville vs. James Madison radio station
- Radio channel: SiriusXM
Listen live to Louisville vs. James Madison live on SiriusXM via channel 84 (Cardinals broadcast).
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Louisville Cardinals 2025 Schedule
| Date | Opponent | Time (ET) |
|---|---|---|
| Sep. 5 | vs. James Madison Dukes | 7:00 p.m. |
| Sep. 20 | vs. Bowling Green Falcons | TBD |
| Sep. 27 | at Pittsburgh Panthers | TBD |
| Oct. 4 | vs. Virginia Cavaliers | TBD |
| Oct. 17 | at Miami Hurricanes | 7:00 p.m. |
| Oct. 25 | vs. Boston College Eagles | TBD |
| Nov. 1 | at Virginia Tech Hokies | TBD |
| Nov. 8 | vs. California Golden Bears | TBD |
| Nov. 14 | vs. Clemson Tigers | 8:00 p.m. |
| Nov. 22 | at SMU Mustangs | TBD |
| Nov. 29 | vs. Kentucky Wildcats | TBD |
| Dec. 6 | ACC Championship | 8:00 p.m. |
James Madison Dukes 2025 Schedule
| Date | Opponent | Time (ET) |
|---|---|---|
| Sep. 5 | at Louisville Cardinals | 7:00 p.m. |
| Sep. 13 | OFF | - |
| Sep. 20 | at Liberty Flames | 6:00 p.m. |
| Sep. 27 | vs. Georgia Southern Eagles | TBA |
| Oct. 4 | at Georgia State Panthers | TBA |
| Oct. 11 | vs. Louisiana Ragin' Cajuns | TBA |
| Oct. 18 | vs. Old Dominion Monarchs | TBA |
| Oct. 25 | OFF | - |
| Oct. 28 | at Texas State Bobcats | 8:00 p.m. |
| Nov. 8 | at Marshall Thundering Herd | TBA |
| Nov. 15 | vs. Appalachian State Mountaineers | TBA |
| Nov. 22 | vs. Washington State Cougars | TBA |
| Nov. 29 | at Coastal Carolina Chanticleers | TBA |
| Dec. 5 | Sun Belt Championship | 7:00 p.m. |