It’s the late-round picks that win fantasy football championships, and that’s also typically where D/STs are selected. Our 2022 college fantasy football defense rankings can help with these important roster additions, whether you're looking for a top unit or a sleeper.
The obvious defensive standouts are Alabama, Clemson, and Georgia, among others, but don't overlook lesser-known squads to the casual fans. For instance, Utah, Cincinnati, and Appalachian State consistently rank high in fantasy football production.
While talent will always rule the day, strength of schedule is also an important component that gets factored in to our rankings. Group of 5 D/STs can have an edge there, which is why you should keep them in mind.
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DOMINATE YOUR NFL FANTASY DRAFT: Ultimate 2022 Cheat Sheet
College Fantasy Football Defense Rankings 2022: Top D/STs, sleepers
2022 COLLEGE FANTASY RANKINGS:
QBs | RBs | WRs | TEs | Kickers | Top 200
| Rank | Player | Conf | Bye |
| 1 | Alabama | SEC | 9 |
| 2 | Clemson | ACC | 9 |
| 3 | Georgia | SEC | 8 |
| 4 | Texas A&M | SEC | 7 |
| 5 | Ohio State | B1G | 7 |
| 6 | Iowa | B1G | 7 |
| 7 | Michigan | B1G | 8 |
| 8 | Cincinnati | AAC | 7 |
| 9 | Wisconsin | B1G | 9 |
| 10 | Utah | P12 | 8 |
| 11 | Appalachian State | SBC | 7 |
| 12 | Boise State | MW | 7 |
| 13 | Penn State | B1G | 6 |
| 14 | Notre Dame | IND | 5 |
| 15 | Baylor | B12 | 6 |
| 16 | Oklahoma State | B12 | 4 |
| 17 | Pittsburgh | ACC | 7 |
| 18 | Middle Tennessee | CUSA | 8 |
| 19 | San Diego State | MW | 7 |
| 20 | Houston | AAC | 7 |
| 21 | Nevada | MW | 5,10 |
| 22 | Louisiana-Lafayette | SBC | 6 |
| 23 | UTSA | CUSA | 9 |
| 24 | Toledo | MAC | 10 |
| 25 | North Carolina State | ACC | 8 |
| 26 | Fresno State | MW | 4 |
| 27 | Auburn | SEC | 8 |
| 28 | Arizona State | P12 | 7 |
| 29 | Michigan State | B1G | 8 |
| 30 | Kansas State | B12 | 7 |