As Week 17 approaches, the NFL's marquee performers are positioned for explosive outings across a schedule packed with compelling individual matchups. Elite quarterbacks Josh Allen and Jalen Hurts headline what could be the game of the week in Buffalo, while dynamic receivers like Ja'Marr Chase and A.J. Brown face defensive units that have shown vulnerability in the secondary. The ground game features intriguing duels, with Jonathan Taylor and Travis Etienne Jr. Set to clash in a crucial divisional battle at Lucas Oil Stadium.
Week 17 NFL Player Props Picks
This weekend's slate presents a fascinating mix of exploitable matchups and stern defensive tests. The Arizona Cardinals and Cincinnati Bengals defenses have proven generous to opposing passing attacks throughout the season, creating prime opportunities for receivers like Chase, Tee Higgins, and tight end Trey McBride to rack up significant yardage. Conversely, running backs will encounter formidable challenges against the Jacksonville Jaguars' stingy run defense, while quarterbacks must navigate the pressure packages deployed by the Buffalo Bills and Philadelphia Eagles.
Understanding these situational advantages is crucial for uncovering value in the player prop market. Which superstars are primed to explode against favorable matchups, and which elite talents might struggle against lockdown defensive schemes? Our comprehensive breakdown identifies the single best player prop bet for each team on this week's schedule.
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Best NFL Player Props Picks for Every Team in Week 17
Breaking down each matchup to identify the most compelling player prop wager for every team on the weekend slate.
| Team | Opponent | Best Player Bet | Prop Pick (Line & Odds) |
|---|---|---|---|
| ARI | @ CIN | Trey McBride | Over 71.5 Receiving Yards (-112) |
| BUF | PHI | Josh Allen | Over 196.5 Passing Yards (-112) |
| CIN | ARI | Ja'Marr Chase | Over 87.5 Receiving Yards (-111) |
| IND | JAX | Jonathan Taylor | Over 76.5 Rushing Yards (-110) |
| JAX | @ IND | Travis Etienne Jr. | Over 63.5 Rushing Yards (-113) |
| PHI | @ BUF | A.J. Brown | Over 61.5 Receiving Yards (-114) |
Fearless Forecasts: Top Props of the Week
After dissecting every angle, several props emerge as the most compelling wagers on the board. These represent our highest-confidence plays for the weekend.
Josh Allen (BUF) - Over 196.5 Passing Yards (-112)
This number screams value for a quarterback of Allen's caliber, especially with recent social media buzz highlighting his superhero-like playmaking ability. Despite nursing a minor foot injury that kept him out of Tuesday's practice, Allen quickly dismissed concerns and declared himself ready for the Eagles clash.
Even against Philadelphia's aggressive defense, this passing total appears too conservative for Buffalo's offensive centerpiece. Allen's Pro Bowl selection underscores his consistent production, and in a marquee non-conference showdown, expect the Bills to lean on his arm talent to move the chains. The modest line creates an excellent entry point for backing one of the league's most dynamic signal-callers.
Ja'Marr Chase (CIN) - Over 87.5 Receiving Yards (-111)
Chase enters a dream matchup against Arizona's vulnerable secondary at Paycor Stadium. The Cardinals have consistently surrendered chunk plays through the air, making this a prime spot for Cincinnati's explosive wideout.
As Joe Burrow's clear-cut number-one target, Chase commands a massive target share in the Bengals' passing attack. His ability to turn routine receptions into big gains makes this yardage total very achievable, particularly in a game environment that projects favorably for offensive production.
A.J. Brown (PHI) - Over 61.5 Receiving Yards (-114)
This line appears disrespectful for an alpha receiver of Brown's stature. While Buffalo's defense presents challenges, Brown's physicality and contested-catch ability make him a constant threat to break loose for significant yardage.
In a high-stakes road environment, Jalen Hurts will need his top weapon to step up, and Brown's track record suggests he thrives in these situations. The modest total creates an attractive risk-reward proposition for backing Philadelphia's premier pass-catcher.
Matchup Breakdowns & Player Prop Analysis
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Arizona Cardinals @ Cincinnati Bengals
This December 28 showdown at Paycor Stadium sets up as an offensive showcase, with both teams featuring elite pass-catchers facing defenses that have struggled to limit aerial attacks.
Arizona Cardinals - Trey McBride Over 71.5 Receiving Yards (-112)
McBride has emerged as a reliable target in Arizona's passing game. Cincinnati's defense has been particularly generous to tight ends this season. With the Cardinals likely needing to throw frequently to keep pace, McBride's role in the intermediate passing game makes this total very achievable. His route-running precision from the slot and seam positions should create multiple opportunities against a Bengals secondary that has shown vulnerability over the middle.
Cincinnati Bengals - Ja'Marr Chase Over 87.5 Receiving Yards (-111)
Chase faces an ideal matchup against Arizona's pass defense, which has performed in the middle of the league in limiting passing yards. The Cardinals' defense presents a matchup that could play directly into Chase's skill set.
At home, the Bengals should have plenty of opportunities to attack downfield, and Chase's big-play ability makes him a threat to clear this total on just a few receptions. His chemistry with Joe Burrow in the red zone and on third-down situations adds multiple avenues to accumulate yardage.
Jacksonville Jaguars @ Indianapolis Colts
The December 28 divisional clash at Lucas Oil Stadium features two of the AFC's most productive running backs in contrasting situations, with both players facing interesting prop opportunities.
Jacksonville Jaguars - Travis Etienne Jr. Over 63.5 Rushing Yards (-113)
Etienne Jr. Carries significant volume as Jacksonville's primary ball-carrier, making this a reasonable total despite the road environment. The Colts' run defense has performed strongly this season, allowing an average of 3.82 rushing yards per attempt, which is among the lowest in the league.
Etienne's receiving ability out of the backfield also provides additional opportunities to accumulate yards, as Jacksonville often utilizes him on swing routes and checkdowns. His workload should remain substantial in a divisional game where ball control could prove crucial.
Indianapolis Colts - Jonathan Taylor Over 76.5 Rushing Yards (-110)
This represents a bet on elite talent overcoming a challenging matchup. Jacksonville's run defense has been among the league's stingiest, but Taylor's combination of power and vision will be tested by the tough front. At home, the Colts will likely commit to establishing their ground game early, giving Taylor multiple opportunities to find running lanes. His ability to break tackles and turn short gains into longer runs makes him capable of surpassing this total even against a stout defensive front.
Philadelphia Eagles @ Buffalo Bills
The marquee matchup of the weekend pits two championship contenders against each other at Highmark Stadium on December 28, featuring elite quarterbacks and playmakers on both sides.
Philadelphia Eagles - A.J. Brown Over 61.5 Receiving Yards (-114)
Brown's physical style and route-running prowess make him ideally suited to attack Buffalo's aggressive defensive scheme. The Bills tend to play tight coverage, which can create opportunities for contested catches where Brown excels. In a road environment where the Eagles will need big plays, Jalen Hurts will look to his most trusted target. Brown's ability to win at the catch point and create separation after contact gives him multiple ways to reach this modest yardage total.
Buffalo Bills - Josh Allen Over 196.5 Passing Yards (-112)
Despite dealing with a minor foot injury earlier in the week, Allen is officially listed with limited participation in practice but appears ready for this crucial matchup. Philadelphia's defense will present challenges, but Allen's dual-threat ability and pocket presence have consistently produced against elite competition.
Former All-Pro Jeff Saturday's recent praise of Allen as "the more dynamic playmaker" in high-stakes environments reinforces the quarterback's ability to rise to the occasion. In a game that could determine playoff seeding, expect Allen to shoulder a significant portion of Buffalo's offensive load through the air.