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Rams vs. Seahawks predictions: NFC Championship Game best bets, opening odds, picks against the spread, moneyline, total

Tim Heaney

Rams vs. Seahawks predictions: NFC Championship Game best bets, opening odds, picks against the spread, moneyline, total image

Jayne Kamin-Oncea-Imagn Images

NFC West rivals meet for the third time in the 2025-26 NFL season... This time, with a berth to Super Bowl 60 on the line.

The No. 1 Seattle Seahawks host the No. 5 Los Angeles Rams on Sunday at 6:30 p.m. ET in the NFC Championship Game.

They split the first two meetings of the year: The Rams prevailed 21-19 in Week 11 by forcing four interceptions from Seahawks quarterback Sam Darnold. However, the embattled QB struck back with the game-winning TD pass and 2-point conversion in an instant-classic 38-37 overtime win in Week 16.

With Seattle's brilliant defense, dangerous (though now depleted) running game, and arguably the league's best receiver in Jaxon Smith-Njigba, Darnold could reach his first Super Bowl. However, he will have to go through former Lombardi Trophy lifter Matthew Stafford and a stacked Rams squad with plenty of postseason experience.

Can Mike Macdonald's Seahawks live up to their top-seeded billing, or is backing them to beat Sean McVay's seasoned squad what a fool believes?

I'll see if I'm a wise man who has the power to reason away the winner of this year's NFC Championship. Keep scrolling for NFL betting predictions and the best odds to wager for Sunday's Seahawks vs. Rams main event.

Seahawks vs. Rams best bet

Under 47.5 (-110) • BetMGM Sportsbook / bet365 Sportsbook

Read more about the Rams vs. Seahawks bet below and use our BetMGM promo code to sign up and bet.

Rams vs. Seahawks betting odds

For this list, I'm using DraftKings Sportsbook odds for the NFC Championship Game, current as of Monday at 9:15 p.m. ET.

I will not necessarily use these odds for finding the best bets for deciding who will win the NFC. (Learn why bettors should use multiple sportsbook apps.)

  • Moneyline: Rams (+130) • Seahawks (-155)
  • Spread (ATS): Rams +2.5 (-105) • Seahawks -2.5 (-115)
  • Total: Over 47.5 (-105) • Under 47.5 (-115)
  • Implied Point Totals Score: Seahawks 25, Rams 22.5

🏆 MORE: Patriots vs. Broncos predictions and oddsSuper Bowl 60 odds and best bets

Rams vs. Seahawks predictions and betting angles: Who will win the NFC Championship Game?

More importantly than analyzing betting trends, which are often deployed in betting punditry universally without context, bettors should consider what angles can affect the event action and follow a betting trail from that.

Here's how NFC Championship Game bettors should approach this contest.

Seahawks lose their bruising back for the rest of the playoffs

Zach Charbonnet is believed to have suffered a torn ACL in the Divisional Round and will miss the rest of the postseason. 

The thunder to Kenneth Walker III's lightning was an integral reason Seattle has been able to optimize Darnold's game, having served as Seattle's best red-zone contributor.

Converted wide receiver Velus Jones Jr. (6-foot, 204 pounds) will act as Seattle's top change-of-pace back, and he's flashed explosiveness in fleeting work.

Puka Nacua celebrates his first TD with teammates versus Seahawks (Week 16, 2025)

© Steven Bisig-Imagn Images

Biggest mismatch: Wide receivers vs. Defensive backfields, on both sides

Though Seattle's Devon Witherspoon is ranked as Pro Football Focus' No. 1 cornerback, both sides carry burnable names in their defensive backfield.

Prop bets should display confidence in Puka Nacua, who torched Seattle in Week 16 for 12 catches, 225 yards, and two touchdowns.

The likelier receiver to falter will be Davante Adams, who likely will draw Witherspoon for much of the game, as well.

Meanwhile, the Rams' cornerbacks have little to offer in terms of shadowing, meaning Smith-Njigba holds a major advantage. 

Beyond JSN, though, the erratic Cooper Kupp-Rashid Shaheed supporting combo may not be able to take advantage as much as it should. Perhaps tight end AJ Barner will chew up key targets.

NFC Championship Game score prediction: Seahawks 23, Rams 20

Even without Charbonnet, Seattle will control possession via Walker, who's enjoying a true breakout season as an impending free agent.

Walker and JSN should prove capable of owning the stat sheets enough to limit Darnold's mistakes and let the defense rush the statuesque Stafford -- yes, even against arguably the league's best offensive line.

🏅 MORE: See where Seahawks and Rams stars rank in Super Bowl 60 MVP odds.

Rams vs. Seahawks bet on the Over/Under total

Under 47.5 (-110) • BetMGM Sportsbook / bet365 Sportsbook

The second matchup totaled a whopping 75 points. The previous? 40.

Sure, there's ample talent on both sides of the football, but side with the defenses, especially in light of the Charbonnet injury.

Let's take advantage of the highest total and the best juice. (Haven't signed up yet? Use our bet365 promo code.)

  • If you want to go with an Under 46.5 bet at (+100) odds, theScore Bet is offering this higher-risk, higher-reward price. Sign up with the best theScore Bet promo code to place this bet.

Rams vs. Seahawks spread bet (ATS)

Seahawks -2.5 (-114) • FanDuel Sportsbook / Caesars Sportsbook

Should we trust Darnold? We trust the defense, JSN, and Walker. That's enough.

If you've already placed the bet with your FanDuel account, try our Caesars Sportsbook promo code to diversify.

Rams vs. Seahawks moneyline bet to win

Pass.

Looking for more value in betting a Seattle win? Bet the spread or an alternative ATS market if you're supremely confident.

Rams vs. Seahawks betting trends data

Again, these should not be considered gospel but can help inform betting decisions on the fringes. Stats include postseason games.

Of course, Denver's trends can be thrown out now that Stidham has to replace Nix.

  • ATS record 2025: Rams 12-7 • Seahawks 13-5
  • Over/Under record 2025: Rams 11-8 • Seahawks 10-8

📋 MORE: How sportsbooks set betting lines

Best sportsbook apps for NFC Championship Game bets that may be available in your area

Even if sports betting is legal in your state, not all sportsbooks may be available to you. Here are some of the most popular options to look into: 

  • DraftKings
  • FanDuel
  • Fanatics
  • BetMGM
  • bet365
  • Caesars
  • theScore Bet
  • Hard Rock Bet
  • Betr
  • BetRivers

🆓 MORE: How to use bonus bets when signing up for a sportsbook

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