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Lions vs Rams Betting Picks and Predictions: Why We Like the Lions to Cover

Alex Payton

Lions vs Rams Betting Picks and Predictions: Why We Like the Lions to Cover image

© Rob Schumacher/The Republic / USA TODAY NETWORK via Imagn Images

The NFL's most compelling quarterback reunion story takes center stage on December 14th when the Detroit Lions visit the Los Angeles Rams at SoFi Stadium. Nearly four years after the blockbuster trade that sent Matthew Stafford west and Jared Goff east, both signal-callers have found their groove in dramatically different ways. This isn't just another Week 15 matchup—it's a clash between two of the league's most explosive offenses with significant playoff implications hanging in the balance.

 

Lions vs Rams Betting Picks and Predictions

The Lions roll into Los Angeles averaging a blistering 30.0 points per game, while the Rams aren't far behind at 29.2 points per contest. Both teams boast elite playmakers, from Amon-Ra St. Brown's consistent production in Detroit to the dynamic duo of Davante Adams and Puka Nacua terrorizing defenses in Los Angeles.

With identical red zone touchdown conversion rates of 66.7% and nearly matching third-down efficiency, this game has all the makings of a classic offensive shootout. The stakes couldn't be higher as both teams jockey for prime playoff positioning in a loaded NFC conference.

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Lions vs Rams Betting Odds

Date: December 14, 2025
Kickoff Time: 4:25 PM EST
Venue: SoFi Stadium, Inglewood, CA

This late-afternoon NFC conference battle promises fireworks under the California sun. Here's how the oddsmakers see this heavyweight matchup unfolding:

  • Moneyline: Rams -250 | Lions +205
  • Spread: Rams -6 (-110) | Lions +6 (-110)
  • Total (Over/Under): 54.5 (Over -120 | Under +100)

Betting odds courtesy of DraftKings.

The Rams enter as substantial home favorites, laying six points against their former quarterback's current squad. The game total has climbed significantly from its opening number of 48.5 to 54.5, reflecting the offensive firepower both teams possess. Bettors are clearly expecting a high-scoring affair when these two prolific attacks take the field.

Statistical Breakdown: Two Mirror Images Ready to Collide

When you dive into the numbers, these teams are remarkably similar—almost eerily so. The Lions hold a slight scoring edge at 30.0 points per game compared to the Rams' 29.2, while Detroit also generates marginally more total yardage (378.7 vs. 373.2 yards per game). The fascinating difference lies in their offensive DNA: Detroit leans heavily on their ground attack, churning out 135.8 rushing yards per contest, while Los Angeles prefers to attack through the air with 249.2 passing yards per game.

The efficiency metrics tell an incredible story of two teams built from the same blueprint. Both squads convert an identical 66.7% of their red zone opportunities into touchdowns, and their third-down conversion rates are separated by just two-tenths of a percent (Rams 38.8%, Lions 38.6%).

Defensively, the pass rush battle will be captivating. The Lions have recorded 37 sacks this season, just one more than the Rams' 36. Los Angeles has been slightly more opportunistic in creating turnovers, generating 20 takeaways compared to Detroit's 16, giving them a marginal edge in turnover differential (+9 vs. +8).

The X-factor could be Detroit's rushing attack, spearheaded by Jahmyr Gibbs, who exploded for three touchdowns in his last outing. This ground game will test a Rams defense that's been vulnerable against physical running attacks. On the flip side, Puka Nacua's two-touchdown performance last week highlights the aerial threat Los Angeles poses to a Lions secondary that's been opportunistic with 11 interceptions this season.

Lions vs. Rams Prediction: Why Detroit Gets the Nod

 

This feels like a classic case of the betting market overvaluing home-field advantage between two evenly matched teams. When you're dealing with squads this statistically similar—virtually identical in turnover differential, red zone efficiency, and overall offensive production—a six-point spread seems generous for the home team.

The Lions have proven they can hang with anyone, averaging a league-leading 30.0 points per game. Their balanced attack, anchored by Gibbs' explosive playmaking ability, gives them multiple ways to move the ball against a Rams defense that's shown vulnerability. Detroit's ability to control the clock with their rushing attack while still possessing big-play capability through the air makes them incredibly dangerous as road underdogs.

The game total of 54.5 points also creates an intriguing opportunity. With both offenses humming at such a high level and defensive numbers that suggest scoring opportunities will be plentiful, this has shootout written all over it.

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Best Bet: Lions +6 (-110)
Best Prop: Jahmyr Gibbs Over 116.5 Rushing + Receiving Yards (-115)

Gibbs is Detroit's most dynamic weapon and should see heavy usage in what projects to be a high-scoring game script. His dual-threat ability makes him an ideal target for exceeding this number, especially considering Detroit's commitment to their ground game (1,766 rushing yards this season) and Gibbs' recent hot streak.

Staff Writer