If you purchase a product or register for an account through one of the links on our site, we may receive compensation. Learn more >

How to Bet Every NFL Week 10 Game Against the Spread

Alex Payton

How to Bet Every NFL Week 10 Game Against the Spread image

© Kiyoshi Mio-Imagn Images

After a less-than exhilarating Thursday Night Football game, we are on to the rest of the NFL Week 10 slate. We have 13 games remaining, with four teams being on a bye. Below, we make ATS picks for each matchup.

NFL ATS Picks for Week 10

 

The next game is in Berlin, Germany. And action ends with two great primetime battles. Make the following NFL against the spread picks using bonuses on some of the top sportsbook apps, like BetMGM and DraftKings.

Falcons vs. Colts

This is the game being played in Berlin, starting at 9:30 a.m. ET. Both teams are coming off a loss last week, while the Falcons have lost three straight games. The Colts made their team better at the deadline, acquiring CB Sauce Gardner, but the guess here is it stays within a touchdown.

Pick: Falcons +6.5 (-108) FanDuel

Saints vs. Panthers

The Panthers have quietly been on a roll, winners of four of their last five games. They had an impressive win over the Packers last week, while the Saints sold at the deadline and are onto the Tyler Shough ERA after benching Spencer Rattler. Despite the box score, on film Shough did not look horrible, and the Panthers are still hard to trust even during this win streak.

Pick: Panthers +5.5 (-110) BetMGM

Giants vs. Bears

The Bears won one of the wildest games you will see last week over the Bengals, winning 47-42 after multiple late touchdowns from both teams. Jaxson Dart has been fun for the Giants, but they are at a supreme talent disadvantage, while the Bears offense might have figured some things out.

Pick: Bears -4.5 (-105) FanDuel

Jaguars vs. Texans

The Texans will be without C.J. Stroud in this game due to a concussion. That said, the best unit in this game, by far, is the Texans defense, which might be the best defense in the NFL. The Jaguars are likely to be missing their top two wideouts in this game in Brian Thomas Jr and Travis Hunter, so we'll trust the Texans defense to carry Houston here.

Pick: Texans +1.5 (-115) DraftKings

Bills vs. Dolphins

This is a large spread for a divisional game, but the Bills are not shy to blow teams out, and are certainly not shy to blow the Dolphins out. The Bills have won three of their last five games against the Dolphins by 10+ points, including two of them by 20+ points. With the Dolphins season going downhill, the Bills win again Sunday.

Pick: Bills -9.5 (-105) FanDuel

Ravens vs. Vikings

Both teams got their starting QBs back last week, with J.J. McCarthy returning from a sprained ankle and Lamar Jackson from a hamstring injury, both in winning efforts as well. The Vikings defense looked fantastic last week against the Lions, and, while Lamar Jackson is a different animal, the guess here is that this game stays within a field goal.

Pick: Vikings +4.5 (-115) Fanatics

Browns vs. Jets

It’s 2-6 vs. 1-7 in this one, making this a game for the real sickos out there. The difference is the Browns have a good defense, while the Jets have a good... Draft pick arsenal over the next couple years. Next.

Pick: Browns -2 (-109) Caesars

Patriots vs. Buccaneers

 

This is quietly a great game between two 2-loss teams. The Bucs are coming off their bye and sit at 6-2 on the year, while the Patriots are 7-2, winners of six straight. The bye week could not have come at a better time for the Bucs, who needed the week off to get healthy. While they are not getting Bucky Irving or Chris Godwin back, we like for them to end the Patriots win streak Sunday.

Pick: Buccaneers -2.5 (-110) BetMGM

Cardinals vs. Seahawks

The Cardinals are officially making the switch to Jacoby Brissett as their starting QB. While Kyler Murray was put on IR with a foot injury, Cardinals head coach Jonathan Gannon said Brissett would be the starter even if Murray was healthy.

That move made sense, as Brissett significantly outplayed Murray this year.They’ll keep it close again against a great Seattle team.

Pick: Cardinals +7 (-115) BetMGM

Rams vs. 49ers

The 49ers won the first matchup between these two teams this year, but that was a flukey game where the Rams had multiple turnovers deep in 49ers territory. Some metrics have the Rams as the best team in the NFL, with a top three offense and top five defense according to DVOA. The 49ers have had the worst injury luck of any team this year, and it is hard to imagine them keeping up with the Rams in this game.

Pick: Rams -4.5 (-110) BetMGM

Lions vs. Commanders

 

One team that has also been snake-bitten this year is the Commanders, who have been without QB Jayden Daniels and WR Terry McLaurin for most of the year. They have the unfortunate circumstance of having to travel to Detroit with the Lions coming off the loss. Let's also not forget that this same Commanders team ended the Lions season in the Divisional Round of the playoffs last year. This has blowout written all over it.

Pick: Lions -7.5 (-115) DraftKings

Steelers vs. Chargers

The Steelers are coming off one of the most impressive wins of the season last week, a dominant victory over the Colts. The Chargers offense has been playing well, but they are dealing with multiple injuries at their OT position, which is hard to survive. Steelers in an upset here, both straight up and covering the spread.

Pick: Steelers +3 (-115) Fanatics

Eagles vs. Packers

The Packers are one of the most confounding teams in the NFL this season, as they can go from looking like a Super Bowl favorite to a fringe playoff team seemingly week-to-week. They have lost two games this year, and those losses are to the Browns and Panthers. The Eagles, meanwhile, are coming off a bye week seemingly in the best position to make a run than they have been this entire season. They made some acquisitions at the trade deadline and are getting some key pieces back healthy.

Pick: Eagles +2.5 (-110) DraftKings

Contributing Writer