Manchester City have been dealt a major blow ahead of Sunday's Manchester derby, with striker Omar Marmoush ruled out of the clash after sustaining a knee injury.
The 26-year-old was injured while on international duty with Egypt in a World Cup qualifier and has now been officially ruled out of the weekend's game.
A club statement confirmed that the forward will now return to Manchester for further assessment and rehabilitation.
Injury update: Omar Marmoush
— Manchester City (@ManCity) September 10, 2025
The news is a major blow for City manager Pep Guardiola, who has been relying on the striker in recent weeks.
Marmoush had started City's previous two Premier League games and his absence will leave a major void in the team's attack.
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The details of Marmoush’s injury
The striker suffered a knee injury in the early stages of Egypt's World Cup qualifying match against Burkina Faso.
He tried to play on after a robust challenge but was forced off the pitch just five minutes later.
Initial scans performed in Egypt indicate a bruised knee ligament, but the full extent of the damage is not yet known.
Marmoush was seen leaving Cairo on crutches, which has raised concerns that his absence could be longer than initially hoped.
The striker will now undergo further tests back in Manchester to determine the full extent of the problem and to begin his rehabilitation.

The impact of Marmoush’s absence on the derby
The absence of Marmoush will be a major blow to Manchester City, as the striker had been a key part of their attack in recent weeks.
Marmoush had started the team's two previous Premier League games and his work rate and technical ability will be sorely missed.
The striker's absence means that Guardiola will now have to rely more heavily on the likes of Jérémy Doku and Phil Foden in attack.
The derby is a must-win for both teams, and the absence of a key player will be a major factor in the game.
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