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Serie A predictions, odds and betting tips for 2025/26 including winner, relegation and top scorer

Alex Lawes

Serie A predictions, odds and betting tips for 2025/26 including winner, relegation and top scorer image

The 2025/26 Serie A season is under way, and there is a lot to look forward to in 2025/26 as the Campeonato in Italy sees Napoli seeking to defend their title.

Antonio Conte led the Neapolitans to their fourth Scudetto last season, but the former Juventus and Chelsea boss will have to balance domestic commitments with a UEFA Champions League run this season; something he has always struggled to do.

That will give hope to the chasing pack as AC Milan and Inter Milan embark upon new eras with Cristian Chivu and Massimiliano Allegri now in situ at San Siro.

Elsewhere, Maurizio Sarri has returned to Lazio, Gian Piero Gasperini has moved from Atalanta to Roma and Igor Tudor begins the campaign under immediate pressure at Juventus.

Drama and entertainment is to be expected throughout in what is arguably Europe’s most fascinating and competitive league, and The Sporting News brings you the latest tips and odds.

MORE: Latest football news from Serie A and other top leagues | Full football fixtures | Serie A table 2025/26

Serie A predictions 2025/26: Title winner

Defending champions Napoli remain the favourites to win the Serie A title once again, with the signings of Sam Beukema, Kevin De Bruyne, Noa Lang and Lorenzo Lucca giving Conte a lot more firepower to fight on all fronts.

Inter are going through a transition period and their squad remains strong, but doubts will remain over manager Chivu, and the same could probably be said for Tudor at Juve.

Milan, with Allegri back in place, could well be the dark horses to be Napoli’s closest challengers, with the Rossoneri coming through an impressive pre-season.

Cremonese have been the big surprise starter after two wins from their opening two games, including an away win at AC Milan, but whether they can maintain that momentum is questionable and their 1500/1 odds with Virgin Bet are an indication of their overall chances.

TeamOddsBet with
Napoli13/8Paddy Power
Inter Milan5/2Sky Bet
Juventus15/2Paddy Power
AC Milan15/2Paddy Power
Roma9/1Betway
Atalanta40/1Bet365
Lazio66/1Betway
Fiorentina66/1Bet Victor

Serie A predictions 2025/26: Relegation candidates

Two of last season’s promoted teams are expected to be relegated according to the odds, with Cremonese — even after their surprise start — and Pisa, now the home of Juan Cuadrado, both expected to struggle this season.

The other promoted side, Sassuolo, should never really have gone down in the first place and the Domenico Berardi-captained Neroverdi may have enough to ease themselves into the mid-table spots.

Hellas Verona and Lecce have been circling the drain for a while and are likely strugglers, as are Cagliari, with Parma embarking upon a new era under Chivu's successor, Carlos Cuesta.

Relegation odds via Bet365
Pisa4/6
Verona1/1
Sassuolo11/10
Cremonese7/4
Lecce7/4
Cagliari9/4
Parma7/2
Genoa4/1
Udinese5/1

Serie A predictions 2025/26: Capocannoniere top scorer

The Capocannoniere is Serie A’s top scorer award. Mateo Retegui was the top scorer last season but the Italy international has since moved to Al Qadsiah.

Inter striker Lautaro Martinez is rated as the favourite, with the 2022 FIFA World Cup winner developing and maturing into one of the very best players in the world in recent years.

Jonathan David has joined Juve on a free transfer from Lille, and he will be expected to be up there, with Moise Kean likely to continue his good form for Fiorentina.

Lorenzo Lucca has a real chance, too, following Romelu Lukaku's injury. He will hope to profit from the service expected to be provided by De Bruyne.

Top scorer odds with Bet365
Lautaro Martinez (Inter Milan)4/1
Moise Kean (Fiorentina)6/1
Jonathan David (Juventus)6/1
Marcus Thuram (Inter Milan7/1
Dusan Vlahovic (Juventus)12/
Lorenzo Lucca (Napoli)16/1

Serie A predictions 2025/26: Top four contenders

The aforementioned title race teams will be expected to be in the top four, but they all have their fallibilities and concerns, potentially opening the door for other contenders such as Roma, who poached Gasperini after the magnificent work he did at Atalanta.

Ivan Juric in at Atalanta, following his relegation with Southampton last season, is expected to contribute to a natural regression from the Bergamasci, and Sarri will be hoping that his settled Lazio side, as a result of a transfer ban, could prove to be a blessing in disguise.

The one team to keep an eye out for this season will be Cesc Fabregas’ Como, who gained promotion in the 2023/24 season and finished last season exceptionally well. The Spaniard has been heavily financially backed in the summer transfer window, too.

Top four odds with Bet365
Napoli1/6
Inter Milan2/7
Juventus1/2
AC Milan4/6
Roma7/5
Atalanta4/1
Bologna4/1
Como9/2
Lazio5/1
Fiorentina5/1

When is the start and end date of the Serie A season 2025/26?

The 2025/26 Serie A season got underway on Saturday, August 23. Serie A likes to stagger the final day of the season so a defined date is not yet in place, but the season will end across the weekend of May 23/24.

How to watch the Serie A 2025/26 season

For the 2025/26 Serie A season in the U.K., you can watch every match live on DAZN, which holds the exclusive streaming rights for all Serie A games in the country.

Additionally, select matches will also be available on TNT Sports 1 and TNT Sports 2 for TV viewing.

For those who prefer digital platforms, matches can be streamed online on Discovery+ with a valid subscription, and some free games will be available via the One Football app and website. Highlights are available on DAZN as well.

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Alex Lawes

Alex Lawes is a freelance content producer for The Sporting News working on betting content for English-language editions. He has been working in sports media since November 2020, whilst still studying at University. He writes primarily on football but has also and does also cover cricket and darts, as well as other sports.