What a difference a week makes as now New Orleans, the top team in the NFC and in pursuit of its sixth straight victory, hosts San Francisco stumbling through its season.
The Saints (6-2) had one of the most impressive victories this season last week in completely dominating Tampa Bay in 38-3 fashion. Wide receiver Michael Thomas made his first return since an injury and suspension sidelined the All-Pro target after Week 1. Thomas didn't have quite the expected impact, only catching 5 passes for 51 yards. In Thomas' absence, the offense has run through running back Alvin Kamara who ranks third in the NFL with 60 receptions and seventh in the league with five rushing touchdowns.
Despite 2020 being a nightmare season for the 49ers (4-5), they are still squarely in the playoff picture even with a litany of injuries the team has had to overcome. Nick Mullens has started the last two weeks in place of the injured Jimmy Garoppolo and has averaged over 264 yards a game and has thrown three total touchdowns. Even while losing stars like Joey Bosa and Solomon Thomas, the 49ers' defense still ranks seventh in the NFL allowing 324.7 yards a game.
The last time the Saints and 49ers met was a classic, with San Francisco defeating New Orleans 48-46 in December 2019 to decide which team would be the 1-seed in the NFC. The Saints have won 7 of the last 10 against San Francisco.
Here's everything you need to know to watch the 49ers vs. Saints game on Sunday, including kickoff time, TV channels and a full Week 10 NFL schedule.
MORE: Watch 49ers vs. Saints live with fuboTV (7-day trial)
What channel is 49ers vs. Saints on today?
- TV channel (national): Fox
- TV channel (San Francisco): KTVU
- TV channel (New Orlens): WVUE
- Live stream: Fox Sports app, fuboTV
Chris Myers and Brock Huard will call the game in the booth with Jennifer Hale reporting from the sidelines. Former NFL Vice President of Officiating Dean Blandino serves as the rules analyst.
For those looking for radio information, the Bills broadcast can be heard on SiriusXM channel 227, or the Seahawks broadcast can be heard on SiriusXM channel 385.
In Canada, viewers can watch 49ers vs. Saints on DAZN, which has rights to every NFL game.
49ers vs. Saints start time
- Date: Sunday, Nov. 15
- Kickoff: 1 p.m. ET
49ers vs. Saints is scheduled to start at 1 p.m. ET, one of four regional early games on Fox. The Northwest, western New York and parts of New England will have access to the game on Fox. The rest of the country will have access to Panthers at Chiefs, Giants at Washington or Bears at Titans.
MORE: NFL Week 10 TV coverage map
NFL schedule Week 10
Thursday, Nov. 12
| Game | Time (ET) | TV channel |
| Colts at Titans | 8:20 p.m. | Fox, fuboTV |
Sunday, Nov. 15
| Game | Time (ET) | TV channel |
| Buccaneers at Panthers | 1 p.m. | Fox, fuboTV |
| Texans at Browns | 1 p.m. | Fox, fuboTV |
| Washington at Lions | 1 p.m. | Fox, fuboTV |
| Jaguars at Packers | 1 p.m. | Fox, fuboTV |
| Eagles at Giants | 1 p.m. | Fox, fuboTV |
| Bills at Cardinals | 4:05 p.m. | CBS, fuboTV |
| Broncos at Raiders | 4:05 p.m. | CBS, fuboTV |
| Chargers at Dolphins | 4:05 p.m. | CBS, fuboTV |
| Bengals at Steelers | 4:25 p.m. | Fox, fuboTV |
| Seahawks at Rams | 4:25 p.m. | Fox, fuboTV |
| 49ers at Saints | 4:25 p.m. | Fox, fuboTV |
| Saints at Buccaneers | 8:20 p.m. | NBC, fuboTV |
Monday, Nov. 16
| Game | Time (ET) | TV channel |
| Vikings at Bears | 8:15 p.m. | ESPN, fuboTV |
49ers schedule 2020
| Week | Date | Opponent | Kickoff time | TV |
| 1 | Sept. 13 | Cardinals | 4:25 p.m. | FOX |
| 2 | Sept. 20 | @Jets | 1 p.m. | FOX |
| 3 | Sept. 27 | @Giants | 1 p.m. | FOX |
| 4 | Oct. 4 | Eagles | 8:20 p.m. | NBC |
| 5 | Oct. 11 | Dolphins | 4:05 p.m. | FOX |
| 6 | Oct. 18 | Rams | 8:20 p.m. | NBC |
| 7 | Oct. 25 | @Patriots | 4:25 p.m. | CBS |
| 8 | Nov. 1 | @Seahawks | 4:25 p.m. | FOX |
| 9 | Nov. 5 | Packers | 8:20 p.m. | NFL Network |
| 10 | Nov. 15 | @Saints | 4:25 p.m. | FOX |
| 11 | - | BYE | - | - |
| 12 | Nov. 29 | @Rams | 4:05 p.m. | FOX |
| 13 | Dec. 7 | Bills | 4:25 p.m. | FOX |
| 14 | Dec. 13 | Redskins | 4:25 p.m. | FOX |
| 15 | Dec. 20 | @Cowboys | 8:20 p.m. | NBC |
| 16 | Dec. 26 or Dec. 27 | @Cardinals | TBD | TBD |
| 17 | Jan. 3 | Seahawks | 4:25 p.m. | FOX |
Saints schedule 2020
| Week | Date | Opponent | Kickoff time | TV |
| 1 | Sept. 13 | Buccaneers | 4:25 p.m. | FOX |
| 2 | Sept. 21 | Raiders | 8:15 p.m. | ESPN |
| 3 | Sept. 27 | Packers | 8:20 p.m. | NBC |
| 4 | Oct. 4 | @Lions | 1 p.m. | FOX |
| 5 | Oct. 12 | Chargers | 8:15 p.m. | ESPN |
| 6 | - | BYE | - | FOX |
| 7 | Oct. 25 | Panthers | 1 p.m. | FOX |
| 8 | Nov. 1 | @Bears | 4:25 p.m. | FOX |
| 9 | Nov. 8 | @Buccaneers | 8:20 p.m. | NBC |
| 10 | Nov. 15 | 49ers | 4:25 p.m. | FOX |
| 11 | Nov. 22 | Falcons | 1 p.m. | FOX |
| 12 | Nov. 29 | @Broncos | 4:05 p.m. | FOX |
| 13 | Dec. 6 | @Falcons | 1 p.m. | FOX |
| 14 | Dec. 13 | @Eagles | 4:25 p.m. | FOX |
| 15 | Dec. 20 | Chiefs | 4:25 p.m. | CBS |
| 16 | Dec. 25 | Vikings | 4:30 p.m. | FOX |
| 17 | Jan. 3 | @Panthers | 1 p.m. | FOX |