San Francisco and Los Angeles square off for a divisional rivalry in what is arguably the NFL's best division with playoff ramifications on the line.
The 49ers (4-6) probably don't stand much of a chance of making the playoffs this season, and have lost three games in a row by at least 10 points, but they already beat the Rams in Week 6. While San Francisco is fresh off a bye week, it has only won one game in the past seven seasons immediately after a bye. Rookie wide receiver Brandon Aiyuk has been one of the few offensive bright spots as his five touchdowns are the fifth most among rookies. The offense could receive a needed boost in the form of Raheem Mostert and Deebo Samuel who both missed the 49ers' last three games.
Los Angeles (7-3) is in first place of the NFC West by way of a head-to-head tiebreaker over Seattle. The Rams have the No. 1 defense, allowing 291.9 yards a game but will be without leading tackler Micah Kiser and also safety Sean Rapp. Aaron Donald also hasn't had a tackle in the last two games, a frist for his career. Jared Goff has passed for 300 yards in three straight games, and hasn't reached that mark four consecutive times since the Rams' 2018 Super Bowl season.
The Rams are let to lose a game in their new SoFi Stadium. Kyle Shanahan is 4-0 against the Rams with Jimmy Garoppolo starting at quarterback but 0-3 with anyone else. Nick Mullens will start for San Francisco.
Here's everything you need to know to watch the 49ers vs. Rams game on Sunday, including kickoff time, TV channels and a full Week 12 NFL schedule.
MORE: Watch 49ers vs. Rams live with fuboTV (7-day trial)
What channel is 49ers vs. Rams on today?
- TV channel (national): Fox
- TV channel (San Francisco): KTVU
- TV channel (Los Angeles): KTTV
- Live stream: Fox Sports app, fuboTV
Chris Myers and Brock Huard will call the game in the booth with Jennifer Hale reporting from the sidelines. Former NFL Vice President of Officiating Dean Blandino is the rules analyst.
For those looking for radio information, the Rams broadcast can be heard on SiriusXM channel 227, or the 49ers broadcast can be heard on SiriusXM channel 380.
In Canada, viewers can watch 49ers vs. Rams on DAZN, which has rights to every NFL game.
49ers vs. Rams start time
- Date: Sunday, Nov. 29
- Kickoff: 4:05 p.m. ET
49ers vs. Rams is scheduled to start at 4:05 p.m. ET, one of two regional late games on Fox. Most of the California and parts of Nevada will have access to the game on Fox. The rest of the country will have access to Saints at Broncos.
MORE: NFL Week 12 TV coverage map
NFL schedule Week 12
Thursday, Nov. 16
| Game | Time (ET) | TV channel |
| Texans at Lions | 12:30 p.m. | CBS, fuboTV |
| Washington at Cowboys | 4:30 p.m. | Fox, fuboTV |
Sunday, Nov. 29
| Game | Time (ET) | TV channel |
| Raiders at Falcons | 1 p.m. | CBS, fuboTV |
| Chargers at Bills | 1 p.m. | CBS, fuboTV |
| Giants at Bengals | 1 p.m. | Fox, fuboTV |
| Titans at Colts | 1 p.m. | CBS, fuboTV |
| Browns at Jaguars | 1 p.m. | CBS, fuboTV |
| Panthers at Vikings | 1 p.m. | Fox, fuboTV |
| Cardinals at Patriots | 1 p.m. | Fox, fuboTV |
| Dolphins at Jets | 1 p.m. | CBS, fuboTV |
| Saints at Broncos | 4:05 p.m. | Fox, fuboTV |
| 49ers at Rams | 4:05 p.m. | Fox, fuboTV |
| Chiefs at Buccaneers | 4:25 p.m. | CBS, fuboTV |
| Bears at Packers | 8:20 p.m. | NBC, fuboTV |
Monday, Nov. 30
| Game | Time (ET) | TV channel |
| Seahawks at Eagles | 8:15 p.m. | ESPN, fuboTV |
Tuesday, Dec. 1
| Game | Time (ET) | TV channel |
| Ravens at Steelers | 8 p.m. | NBC, fuboTV |
49ers schedule 2020
| Week | Date | Opponent | Kickoff time | TV |
| 1 | Sept. 13 | Cardinals | 4:25 p.m. | FOX |
| 2 | Sept. 20 | @Jets | 1 p.m. | FOX |
| 3 | Sept. 27 | @Giants | 1 p.m. | FOX |
| 4 | Oct. 4 | Eagles | 8:20 p.m. | NBC |
| 5 | Oct. 11 | Dolphins | 4:05 p.m. | FOX |
| 6 | Oct. 18 | Rams | 8:20 p.m. | NBC |
| 7 | Oct. 25 | @Patriots | 4:25 p.m. | CBS |
| 8 | Nov. 1 | @Seahawks | 4:25 p.m. | FOX |
| 9 | Nov. 5 | Packers | 8:20 p.m. | NFL Network |
| 10 | Nov. 15 | @Saints | 4:25 p.m. | FOX |
| 11 | - | BYE | - | - |
| 12 | Nov. 29 | @Rams | 4:05 p.m. | FOX |
| 13 | Dec. 7 | Bills | 4:25 p.m. | FOX |
| 14 | Dec. 13 | Redskins | 4:25 p.m. | FOX |
| 15 | Dec. 20 | @Cowboys | 8:20 p.m. | NBC |
| 16 | Dec. 26 or Dec. 27 | @Cardinals | TBD | TBD |
| 17 | Jan. 3 | Seahawks | 4:25 p.m. | FOX |
Rams schedule 2020
| Week | Date | Opponent | Time (ET) | TV |
| 1 | Sept. 13 | vs. Dallas Cowboys | 8:20 p.m. | NBC |
| 2 | Sept. 20 | at Philadelphia Eagles | 1 p.m. | Fox |
| 3 | Sept. 27 | at Buffalo Bills | 1 p.m. | Fox |
| 4 | Oct. 4 | vs. New York Giants | 4:05 p.m. | Fox |
| 5 | Oct. 11 | at Washington Redskins | 1 p.m. | Fox |
| 6 | Oct. 18 | at San Francisco 49ers | 8:20 p.m. | NBC |
| 7 | Oct. 26 | vs. Chicago Bears | 8:15 p.m. | ESPN |
| 8 | Nov. 1 | at Miami Dolphins | 1 p.m. | Fox |
| 9 | Bye | |||
| 10 | Nov. 15 | vs. Seattle Seahawks | 4:25 p.m., Fox | |
| 11 | Nov. 23 | at Tampa Bay Buccaneers | 8:15 p.m. | ESPN |
| 12 | Nov. 29 | vs. San Francisco 49ers | 4:05 p.m. | Fox |
| 13 | Dec. 6 | at Arizona Cardinals | 4:05 p.m. | Fox |
| 14 | Dec. 10 | vs. New England Patriots | 8:20 p.m. | Fox |
| 15 | Dec. 19 or 20 | vs. New York Jets | TBD | |
| 16 | Dec. 27 | at Seattle Seahawks | 4:05 p.m. | CBS |
| 17 | Jan. 3 | vs. Arizona Cardinals | 4:25 p.m. | Fox |