49ers injury report: Here's a full list of San Francisco's stars not playing vs. Seahawks

The San Francisco 49ers kept their championship aspirations alive with a hard-fought victory over the Philadelphia Eagles, but the win came at a staggering cost to their offensive identity.

While the 23-19 score reflected postseason advancement, All-Pro tight end George Kittle exiting the field with an Achilles injury cast a somber shadow over the celebration. Kittle, the emotional and physical heartbeat of the Niners, now faces an uphill battle to return next season, leaving a massive void in a lineup that has long relied on his versatility to dominate opponents in the trenches.

The injury to Kittle is just the tip of the iceberg for a San Francisco roster that appears increasingly fragile at the most critical juncture of the season. Several key starters on both sides of the ball have dealt with injuries, and more emerged from the physical slugfest against Philadelphia noticeably banged up. With a rested and explosive Seattle Seahawks squad up next in the Divisional Round, the 49ers’ medical staff is working around the clock to determine who will be healthy enough for the trip to the Pacific Northwest.

Here’s the latest on the status of the 49ers’ stars for the divisional game against the Seahawks.

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49ers injury updates

George Kittle, TE, Achilles

Kittle will not be available for San Francisco not only for the trip to Seattle, but for the forseeable future after suffering a ruptured achilles against the Eagles. This not only puts the tight end out for the rest of the postseason, but most likely a portion of the 2026 regular season as well.

#49ers George Kittle posted for the first time since tearing his Achilles 💔 pic.twitter.com/V5wjt4pElW

— OurSF49ers (@OurSf49ers) January 12, 2026

At 32-years-old, Kittle now faces a steep recovery to get back on the field, let alone at full strength. This comes after he missed games in the regular season with groin, rib and hamstring injuries.

MORE: 49ers vs. Seahawks rivalry history

Fred Warner, RB, Ankle

Though he has worked his way back from a broken and dislocated ankle, Warner will not be available on Saturday for the 49ers.

The superstar linebacker and heartbeat of the 49ers defense missed the rest of the regular season after the injury in Week 6 against the Buccaneers. Warner is back practicing with the team, but coach Kyle Shanahan said that he won't be activated off the injured reserve before the game against the Seahawks.

49ers LB Fred Warner will not be activated off injured reserve ahead of Saturday’s game in Seattle for the divisional round, per HC Kyle Shanahan.

— Adam Schefter (@AdamSchefter) January 15, 2026

MORE: Fred Warner injury update from 49ers confirms status for divisional round

Trent Williams, OT, Hamstring

The 49ers' star left tackle is dealing with a hamstring injury that also had him questionable for the Wild Card game against the Eagles. Though, Williams played in that game and had a significant impact.

Ahead of the game in Seattle, Williams was a full participant in both Wednesday and Thursday's practice, putting him on track to play.

MORE: Why 49ers fear a Sam Darnold Seahawks repeat

Ricky Pearsall, WR, Knee

Pearsall, San Francisco's promising second-year wideout, missed the win against the Eagles, and his status is still questionable for the Divisional Round. Though, he is trending towards playing.

The wide receiver has been a limited participant throughout the week, but when speaking with reporters said he's pretty confident he will play.

#49ers WR Ricky Pearsall says his injury won’t fully heal until he gets real rest and is shut down after the season, adding that explosive movements are the hardest part to deal with.

But, he’s pretty confident he will play 👀
pic.twitter.com/VUaM3KQQI5

— 49ers & NFL News 24/7 (@49ersSportsTalk) January 15, 2026

Pearsall's knee injury has caused him to miss some time this season, but it sounds like he'll be available on Saturday night.

MORE: Kyle Shanahan family tree

Ji'Ayir Brown, CB, Hamstring

Brown injured his hamstring against the Eagles and had to leave the game. He did not return in the 49ers' win, and he will once again be out against the Seahawks.

He is yet to practice since exiting Sunday's contest.

MORE: How NFC West won NFL's 'best division ever'

Dee Winters, LB, Ankle

Winters, the rookie who has taken the majority of linebacker snaps in Warner's absence, is dealing with an ankle injury that has had him limited in practice. Though, he was dealing with the ankle injury during the wild card game as well.

Dee Winters practicing today, Luke Gifford had a helmet on as well. #49ers | #FTTB pic.twitter.com/NEhbZJTuLm

— Matt Lively (@mattblively) January 15, 2026

He is listed as questionable ahead of Saturday's game.

MORE: Christian McCaffrey's injury history

Here is the full list of the 49ers dealing with injuries:

NFL playoff schedule 2026

Wild-card round

Saturday, Jan. 10

Sunday, Jan. 11

Monday, Jan. 12

Divisional round

Saturday, Jan. 17

Sunday, Jan. 18

Conference championships

Sunday, Jan. 25

Super Bowl LX

Sunday, Feb. 8