Khalil Mack has been a steady presence on the Los Angeles Chargers' defensive line ever since he joined the team in 2022. But the Chargers may have to spend some time without him.
In Monday night's matchup against the Las Vegas Raiders, Mack exited with what his team called an elbow injury after making a tackle attempt on wide receiver Tre Tucker.
Mack's arm got twisted as he and linebacker Troy Dye converged on Tucker, and the star defender immediately went to the medical tent.
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Here's the lates on Mack's injury after exiting in Week 2.
MORE: Updates, highlights from Chargers vs. Raiders
Khalil Mack injury update
With the Raiders and Chargers still early on in their Week 2 meeting, Mack and Dye came in on Tucker to make a tackle at the same time. With Dye on his right side, Mack's left arm appeared to get caught right where his teammate was making the tackle attempt, as Dye leaned right into Mack's elbow and caused it to bend backward.
It’s an elbow injury for Khalil Mack. This is where it happened: pic.twitter.com/bhvHBKYMrm https://t.co/QSoUVuy9pE
— Ari Meirov (@MySportsUpdate) September 16, 2025
Mack, facing his former Raiders team, immediately went to the sidelines to enter the medical tent.
Khalil Mack got his left wrist caught in a tackle and runs straight off the field into the tent #NFL pic.twitter.com/3FO0OzBPte
— Tanner Phifer (@TannerPhifer) September 16, 2025
Not long prior to the injury, Mack had registered his first sack of the season, also improving to 12.5 sacks against the Raiders since they traded him.
khalil mack, of course
— Los Angeles Chargers (@chargers) September 16, 2025
📺 @espn pic.twitter.com/pDyzJZAcmp
The Chargers officially ruled Mack questionable to return to the game with an elbow injury. Mack was also seen going back to the locker room.
Khalil Mack is headed to the locker room with an apparent injury. pic.twitter.com/NHbRTrinJA
— FOX Sports: NFL (@NFLonFOX) September 16, 2025
Mack was downgraded to out by the Chargers shortly after. He was seen on the sideline with his left arm in a sling.
I don't think Khalil Mack is returning to this game. pic.twitter.com/EUDeQ60mhY
— Clayton Holloway (@HollowayNFLN) September 16, 2025
While the official extent of his injury remains to be seen, a potential absence for Mack would be a tough blow for Jim Harbaugh's defense. He's totaled 31 sacks in the past three seasons for the Chargers, including 17 in 2023, and Mack earned his ninth Pro Bowl nod last season.
Khalil Mack injury history
Mack has done a lot of things well in his NFL career, and one of them has been staying healthy. To date, he's played in fewer than 16 games in a season just once, in 2021, and he's been known to play through more minor ailments in the past.
According to Draft Sharks, here's the brief breakdown of Mack's previous NFL injuries:
- Sept. 2020: Knee Strain, no time missed
- Sept. 2021: Unspecified left foot injury, missed 10 games