The Oregon Ducksare looking like one of the best teams in the early going of the college football season. They have an explosive playmaker in Dante Moore at quarterback, and a ferocious defense that has allowed just 20 points over their first three games.
On Saturday, the Ducks take on the Oregon State Beavers, their in-state rival. The two teams are no longer in the same conference, but will still square off against one another every year.
Oregon, for the third straight week, is a big favorite against an inferior opponent. However, this will be the last "freebie" for Oregon, as they will head on the road to take on No. 2 Penn State in a huge Big 10 matchup next week.
Oregon State vs. Oregon how to watch, channel
Time: Saturday, Sep 20, 2025, 3:30 p.m. EST
Location: Autzen Stadium, Eugene, Oregon
Channel: Big 10 Network
Oregon State vs. Oregon odds, spread, O/U
Oregon is 3-0, and is continuing to work on whatever they need to be ready and prepared for the big showdown against Penn State next Saturday. Moore has been eased into the offense nicely, and Malik Benson appears to be his top wideout option. Dan Lanning and the rest of the coaching staff have the team fired up and ready to go every week. Now, lets get into the game markets.
Odds courtesy of FanDuel Sportsbook:
Moneyline: OFF
Spread: Oregon -34.5 (-110)
O/U: 56.5 (-110, -110)
Oregon State vs. Oregon prediction, best bets
In last week's contest against Northwestern, Oregon did not cover the spread, but still won 34-14. This week, the spread is at a similar number of 34.5 points, which is a lot. However, my best bet for this game would be to take Oregon -34.5. Oregon is 2-1 against the spread this season, and can beat the brakes off teams if they open up the playbook and run into some quick touchdowns.