JUMP TO:
- Who to start, sit today in fantasy Week 16
- NFL Fantasy Inactives for Week 16
- Fantasy Live News to Know for Week 16 Sunday
- Week 16 rankings
If you've made it to Round 2 of the fantasy football playoffs, then hopefully this weekly article has helped you set your lineups a few times.
Following a crucial Rams-Seahawks clash on Thursday Night Football, this week's schedule now features two fantasy-heavy Saturday night games in the Eagles-Commanders and Packers-Bears.
So we're publishing our Week 16 start-sit analysis early to get a jump on those important decisions.
Monitor these top fantasy stories heading into tonight's games:
- Saturday injury news for Christian Watson, Josh Jacobs, and more
- Which Saints running back will take over: Audric Estime or Evan Hull?
- How many more games will Travis Kelce play?
Scroll down for our expert tips for Week 16 start-sit questions, along with breakdowns of last-minute news that will help you set your lineups that will try to advance you to your fantasy league semifinals.
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Who should I start in fantasy Week 16?
Click to read Vinnie Iyer's full Week 16 Start 'Em Sit 'Em for expanded lineup tips.
Fantasy lineup Week 16 questions answered for half-PPR start-sit lineup tips for Sunday and Monday action:
Fantasy Football Week 16 Must-Starts
QB: Jalen Hurts, Eagles (vs. WAS); Josh Allen, Bills (at CLE); Drake Maye, Patriots (at BAL); Lamar Jackson, Ravens (vs. NE); Justin Herbert, Chargers (at DAL); Jared Goff, Lions (vs. PIT); Brock Purdy, 49ers (at IND)
RB: De'Von Achane, Dolphins (vs. CIN); Bijan Robinson, Falcons (at ARI); Christian McCaffrey, 49ers (at IND); Jahmyr Gibbs, Lions (vs. PIT); James Cook, Bills (at CLE); Saquon Barkley, Eagles (at WAS); Josh Jacobs, Packers (at CHI); Bucky Irving, Buccaneers (at CAR); Jonathan Taylor, Colts (vs. SF); TreVeyon Henderson, Patriots (at BAL); Chase Brown, Bengals (at MIA); Travis Etienne Jr. Jaguars (at DEN); Derrick Henry, Ravens (vs. NE); Omarion Hampton, Chargers (at DAL); Javonte Williams, Cowboys (vs. LAC); D'Andre Swift, Bears (vs. GB); Rico Dowdle, Panthers (vs. TB); Woody Marks, Texans (vs. LV); Breece Hall, Jets (at NO); Jaylen Warren, Steelers (at DET)
WR: Amon-Ra St. Brown, Lions (vs. PIT); Nico Collins, Texans (vs. LV); Ja'Marr Chase, Bengals (at MIA); A.J. Brown, Eagles (at WAS); Mike Evans, Buccaneers (vs. CAR); CeeDee Lamb, Cowboys (vs. LAC); Michael Wilson, Cardinals (vs. ATL); Jameson Williams, Lions (vs. PIT); Jaylen Waddle, Dolphins (vs. CIN); DK Metcalf, Steelers (at DET); Ladd McConkey, Chargers (at DAL); Courtland Sutton, Broncos (vs. JAX); Chris Olave, Saints (vs. NYJ); Jauan Jennings, 49ers (at IND); Tee Higgins, Bengals (if he plays, at MIA); Zay Flowers, Ravens (vs. NE); Terry McLaurin, Commanders (vs. PHI); Tetairoa McMillan, Panthers (vs. TB); DeVonta Smith, Eagles (vs. WAS); Jayden Reed, Packers (at CHI); Jakobi Meyers, Jaguars (at DEN); Justin Jefferson, Vikings (at NYG); Stefon Diggs, Patriots (at BAL)
TE: Trey McBride, Cardinals (vs. ATL); George Kittle, 49ers (at IND); Brock Bowers, Raiders (at HOU); Kyle Pitts, Falcons (at ARI); Travis Kelce, Chiefs (vs. LAC); Jake Ferguson, Cowboys (vs. LAC); Oronde Gadsden II, Chargers (at DAL)
D/ST: Houston Texans (vs. LV); Buffalo Bills (at CLE); Minnesota Vikings (at NYG); New Orleans Saints (vs. NYJ); Kansas City Chiefs (at TEN); Philadelphia Eagles (at WAS); Denver Broncos (vs. JAX); Los Angeles Chargers (at DAL); Jacksonville Jaguars (at DEN); Dallas Cowboys (vs. LAC); New England Patriots (at BAL); Detroit Lions (vs. PIT)
Fantasy Football Week 16 Start 'Em
QB: Bo Nix, Broncos (vs. JAX); C.J. Stroud, Texans (vs. LV); Baker Mayfield, Buccaneers (at CAR); Aaron Rodgers, Steelers (at DET); Jaxson Dart, Giants (vs. MIN); Jacoby Brissett, Cardinals (vs. ATL); J.J. McCarthy, Vikings (at NYG)
RB: Quinshon Judkins, Browns (vs. BUF); Kareem Hunt, Chiefs (at TEN); Audric Estime, Saints (vs. NYJ); David Montgomery, Lions (vs. PIT); Jordan Mason, Vikings (at NYG); Michael Carter, Cardinals (vs. ATL); RJ Harvey, Broncos (vs. JAX)
WR: Michael Pittman Jr., Colts (vs. SF); Deebo Samuel, Commanders (at PHI); D.J. Moore, Bears (vs. GB); Troy Franklin, Broncos (vs. JAX); Godwin, Buccaneers (vs. ATL); Quentin Johnston, Chargers (if he plays, at DAL); Khalil Shakir, Bills (at CLE); Adonai Mitchell, Jets (at NO)
TE: Tyler Warren, Colts (vs. SF); Darren Waller, Dolphins (vs. CIN); Theo Johnson, Giants (at MIN); T.J. Hockenson, Vikings (vs. NYG); Dallas Goedert, Eagles (at WAS); Brenton Strange, Jaguars (at DEN)
Fantasy Football Week 16 Sit 'Em
QB: Joe Burrow, Bengals (at MIA); Dak Prescott, Cowboys (vs. LAC); Trevor Lawrence, Jaguars (at DEN); Jordan Love, Packers (at CHI); Caleb Williams, Bears (vs. GB)
RB: Ashton Jeanty, Raiders (at HOU); Tony Pollard, Titans (vs. KC); Kyle Monangai, Bears (vs. GB); Tyrone Tracy Jr., Giants (vs. MIN); Jacory "Bill" Croskey-Merritt, Commanders (vs. PHI); Kenneth Gainwell, Steelers (at DET)
WR: George Pickens, Cowboys (vs. LAC); Brian Thomas Jr., Jaguars (at DEN); Wan'Dale Robinson, Giants (vs. MIN); Jordan Addison, Vikings (at NYG); Ricky Pearsall, 49ers (at IND); Alec Pierce, Colts (vs. SF); Jayden Higgins, Texans (vs. LV); Emeka Egbuka, Buccaneers (vs. CAR); Darius Slayton, Giants (vs. MIN)
TE: Mark Andrews and Isaiah Likely, Ravens (vs. NE); Dalton Kincaid, Bills (at CLE); Dalton Schultz, Texans (vs. LV); Harold Fannin Jr., Browns (vs. BUF); Evan Engram, Broncos (vs. JAX); Colston Loveland, Bears (vs. GB)
NFL Fantasy Week 16 Inactives
Inactive fantasy players OUT or not expected to play in Week 16
These fantasy names are among either those listed on injured reserve, listed as OUT, or not expected to play this week. Remove them from your Week 15 lineups once confirmed.
To check every player practice report and health designation every week, bookmark our NFL injuries tracker.
- WR Rashee Rice - OUT
- RB Alvin Kamara - OUT
- RB Devin Neal - OUT
- RB Bhayshul Tuten - OUT
- RB Dylan Sampson - OUT
- WR Devaughn Vele - OUT
- TE David Njoku - OUT
- TE Mason Taylor - OUT
NFL Fantasy Week 16 Players ACTIVE, QUESTIONABLE, or EXPECTED TO PLAY
These fantasy names are expected to play in Week 15, but confirm their status before locking them into your lineups.
Stay tuned as questionable, injured players are confirmed to be ready to play in fantasy Week 15 around 11:30 a.m. ET for 1 p.m. Kickoffs, and 2:30-3 p.m. For late-window Sunday games.
EXPECTED TO PLAY for Week 16
- QB Geno Smith
QUESTIONABLE for fantasy Week 15
- RB Josh Jacobs (knee)
- RB Woody Marks (ankle)
- RB Nick Chubb (ribs)
- WR Drake London (knee)
- WR Tee Higgins (concussion)
- WR Marvin Harrison Jr. (Heel)
- WR Christian Watson (chest/shoulder)
- WR Tetairoa McMillan (foot, ankle)
Top Week 16 fantasy news
Travis Kelce will play out rest of Chiefs' season
Despite the club being eliminated from playoff contention, Patrick Mahomes' season-ending knee tears, and many key players resting this week, Kelce will reportedly not step away from on-field action.
His value remains highest in point-per-reception (PPR) games in which him piling up midrange targets will help his longevity, even with Gardner Minshew at quarterback.
MORE:
👀 Watch for updates on major Week 16 fantasy news.
Week 16 fantasy rankings: Should I start these players in my lineup?
This week's fantasy football rankings were updated Friday overnight ET.
We've based these fantasy football rankings on full-point PPR scoring except where otherwise noted.
Week 16 QB Rankings
| Rk | Tr | Name | TM | OPP |
| 1 | 1 | Jared Goff | DET | PIT |
| 2 | 1 | Jalen Hurts | PHI | @WAS |
| 3 | 2 | Drake Maye | NE | @BAL |
| 4 | 2 | Josh Allen | BUF | @CLE |
| 5 | 2 | Lamar Jackson | BAL | NE |
| 6 | 2 | Brock Purdy | SF | @IND |
| 7 | 2 | Matthew Stafford | LAR | @SEA |
| 8 | 3 | Trevor Lawrence | JAX | @DEN |
| 9 | 3 | Sam Darnold | SEA | LAR |
| 10 | 3 | Jacoby Brissett | ARI | ATL |
| 11 | 3 | Bo Nix | DEN | JAX |
| 12 | 3 | Joe Burrow | CIN | @MIA |
| 13 | 4 | Aaron Rodgers | PIT | @DET |
| 14 | 4 | Justin Herbert | LAC | @DAL |
| 15 | 4 | J.J. McCarthy | MIN | @NYG |
| 16 | 5 | Caleb Williams | CHI | GB |
| 17 | 5 | Jordan Love | GB | @CHI |
| 18 | 5 | Dak Prescott | DAL | LAC |
| 19 | 5 | Jaxson Dart | NYG | MIN |
| 20 | 6 | Gardner Minshew | KC | @TEN |
| 21 | 6 | Bryce Young | CAR | TB |
| 22 | 6 | Kirk Cousins | ATL | @ARI |
| 23 | 6 | Tua Tagovailoa | MIA | CIN |
| 24 | 6 | Tyler Shough | NO | NYJ |
| 25 | 7 | C.J. Stroud | HOU | LV |
| 26 | 7 | Shedeur Sanders | CLE | BUF |
| 27 | 7 | Baker Mayfield | TB | @CAR |
| 28 | 7 | Cam Ward | TEN | KC |
| 29 | 7 | Geno Smith | LV | @HOU |
| 30 | 7 | Marcus Mariota | WAS | PHI |
| 31 | 8 | Brady Cook | NYJ | @NO |
| 32 | 8 | Philip Rivers | IND | SF |
| 33 | 9 | Riley Leonard | IND | SF |
| 34 | 9 | Jameis Winston | NYG | MIN |
| 35 | 9 | Dillon Gabriel | CLE | BUF |
| 36 | 10 | Davis Mills | HOU | LV |
| 37 | 10 | Joe Flacco | CIN | @MIA |
| 38 | 10 | Mason Rudolph | PIT | @DET |
| 39 | 11 | Max Brosmer | MIN | @NYG |
| 40 | 11 | Teddy Bridgewater | TB | @CAR |
| 30 | 11 | Kenny Pickett | LV | @HOU |
| 41 | 11 | Tanner McKee | PHI | @WAS |
| 42 | 11 | Trey Lance | LAC | @DAL |
| 43 | 11 | Malik Willis | GB | @CHI |
| 44 | 11 | Jake Browning | CIN | @MIA |
| 45 | 11 | Nick Mullens | JAX | @DEN |
| 46 | 11 | Kedon Slovis | ARI | ATL |
| QUE | -- | Justin Fields | NYJ | @NO |
| QUE | -- | Tyrod Taylor | NYJ | @NO |
| IR | -- | Patrick Mahomes | KC | @TEN |
| IR | -- | Jayden Daniels | WAS | PHI |
| IR | -- | Daniel Jones | IND | SF |
| IR | -- | Kyler Murray | ARI | ATL |
| IR | -- | Michael Penix Jr. | ATL | @ARI |
Week 16 RB Rankings
| Rk | Tr | Name | TM | OPP | Week 16 Value |
| 1 | 1 | Bijan Robinson | ATL | @ARI | Elite RB1 |
| 2 | 1 | James Cook | BUF | @CLE | Elite RB1 |
| 3 | 2 | TreVeyon Henderson | NE | @BAL | Elite RB1 |
| 4 | 2 | Jahmyr Gibbs | DET | PIT | Elite RB1 |
| 5 | 2 | De'Von Achane | MIA | CIN | Elite RB1 |
| 6 | 3 | Saquon Barkley | PHI | @WAS | RB1 |
| 7 | 3 | Jonathan Taylor | IND | SF | RB1 |
| 8 | 3 | Christian McCaffrey | SF | @IND | RB1 |
| 9 | 3 | Tony Pollard | TEN | KC | RB1 |
| 10 | 4 | RJ Harvey | DEN | JAX | RB1/RB2 |
| 11 | 4 | Kyren Williams | LAR | @SEA | DONE-TNF |
| 12 | 4 | D'Andre Swift | CHI | GB | INJ-QUE |
| 13 | 4 | Travis Etienne | JAX | @DEN | RB1/RB2 |
| 14 | 4 | Josh Jacobs | GB | @CHI | INJ-QUE |
| 15 | 4 | Chase Brown | CIN | @MIA | RB1/RB2 |
| 16 | 5 | Aaron Jones | MIN | @NYG | Strong RB2 |
| 17 | 5 | Derrick Henry | BAL | NE | Strong RB2 |
| 18 | 6 | Omarion Hampton | LAC | @DAL | RB2 |
| 19 | 6 | Tyrone Tracy | NYG | MIN | RB2 |
| 20 | 6 | Quinshon Judkins | CLE | BUF | RB2/Flex |
| 21 | 6 | Chris Rodriguez | WAS | PHI | RB2 |
| 22 | 6 | Rico Dowdle | CAR | TB | RB2 |
| 23 | 6 | Breece Hall | NYJ | @NO | RB2 |
| 24 | 7 | Bucky Irving | TB | @CAR | RB2/Flex |
| 25 | 7 | Kareem Hunt | KC | @TEN | RB2/Flex |
| 26 | 7 | Javonte Williams | DAL | LAC | RB2/Flex |
| 27 | 8 | Ashton Jeanty | LV | @HOU | Strong Flex |
| 28 | 8 | Kenneth Walker | SEA | LAR | DONE-TNF |
| 29 | 8 | Blake Corum | LAR | @SEA | DONE-TNF |
| 30 | 8 | Michael Carter | ARI | ATL | Strong Flex |
| 31 | 9 | Jordan Mason | MIN | @NYG | Flex |
| 32 | 9 | Jawhar Jordan | HOU | LV | Flex |
| 33 | 9 | Tyler Allgeier | ATL | @ARI | Flex |
| 34 | 9 | Kenneth Gainwell | PIT | @DET | Flex |
| 35 | 9 | Jaylen Warren | PIT | @DET | Flex |
| 36 | 10 | Evan Hull | NO | NYJ | Flex |
| 37 | 10 | Jacory Croskey-Merritt | WAS | PHI | Flex |
| 38 | 10 | David Montgomery | DET | PIT | Flex |
| 39 | 10 | Keaton Mitchell | BAL | NE | Flex |
| 40 | 10 | Chuba Hubbard | CAR | TB | Flex |
| 41 | 10 | Rhamondre Stevenson | NE | @BAL | Flex |
| 42 | 11 | Audric Estime | NO | NYJ | Flex/Bench |
| 43 | 11 | Dare Ogunbowale | HOU | LV | Flex/Bench |
| 44 | 12 | Kimani Vidal | LAC | @DAL | Flex/Bench |
| 45 | 12 | Devin Singletary | NYG | MIN | Flex/Bench |
| 46 | 12 | Jeremy McNichols | WAS | PHI | Flex/Bench |
| 47 | 12 | Jaylen Wright | MIA | CIN | Flex/Bench |
| 48 | 12 | Isaiah Davis | NYJ | @NO | Flex/Bench |
| 49 | 13 | Tyjae Spears | TEN | KC | Flex/Bench |
| 50 | 13 | Zach Charbonnet | SEA | LAR | DONE-TNF |
| 51 | 13 | Kyle Monangai | CHI | GB | Flex/Bench |
| 52 | 13 | LeQuint Allen | JAX | @DEN | Flex/Bench |
| 53 | 13 | Emanuel Wilson | GB | @CHI | Flex/Bench |
| 54 | 13 | Emari Demercado | ARI | ATL | Flex/Bench |
| 55 | 13 | Malik Davis | DAL | LAC | Flex/Bench |
| 56 | 13 | Samaje Perine | CIN | @MIA | Flex/Bench |
| 57 | 14 | Ray Davis | BUF | @CLE | Bench |
| 58 | 14 | Isiah Pacheco | KC | @TEN | Bench |
| 59 | 14 | Tank Bigsby | PHI | @WAS | Bench |
| 60 | 14 | Sean Tucker | TB | @CAR | Bench |
| 61 | 14 | Rachaad White | TB | @CAR | Bench |
| 62 | 14 | Ollie Gordon | MIA | CIN | Bench |
| 63 | 14 | Zavier Scott | MIN | @NYG | Bench |
| 64 | 14 | Hunter Luepke | DAL | LAC | Bench |
| 65 | 14 | Ty Johnson | BUF | @CLE | Bench |
| 66 | 14 | Ameer Abdullah | IND | SF | Bench |
| 67 | 14 | C.J. Ham | MIN | @NYG | Bench |
| 68 | 15 | Ronnie Rivers | LAR | @SEA | DONE-TNF |
| 69 | 15 | Clyde Edwards-Helaire | KC | @TEN | Bench |
| 70 | 15 | Sione Vaki | DET | PIT | Bench |
| 71 | 15 | Brian Robinson | SF | @IND | Bench |
| 72 | 15 | Velus Jones | SEA | LAR | DONE-TNF |
| 73 | 15 | Tyler Badie | DEN | JAX | Bench |
| 74 | 15 | Chris Brooks | GB | @CHI | INJ-QUE |
| 75 | 15 | Raheem Mostert | LV | @HOU | Bench |
| 76 | 15 | Jaleel McLaughlin | DEN | JAX | Bench |
| 77 | 15 | Trayveon Williams | CLE | BUF | Bench |
| 78 | 15 | Rasheen Ali | BAL | NE | Bench |
| 79 | 15 | Brashard Smith | KC | @TEN | Bench |
| 80 | 15 | Adam Prentice | DEN | JAX | Bench |
| 81 | 16 | Corey Kiner | ARI | ATL | Bench |
| 82 | 16 | Owen Wright | TB | @CAR | Bench |
| 83 | 16 | Myles Gaskin | SEA | LAR | DONE-TNF |
| 84 | 16 | Andrew Beck | NYJ | @NO | Bench |
| 85 | 16 | Khalil Herbert | NYJ | @NO | Bench |
| 86 | 16 | Tahj Brooks | CIN | @MIA | Bench |
| 87 | 16 | Kaleb Johnson | PIT | @DET | Bench |
| 88 | 16 | Dylan Laube | LV | @HOU | Bench |
| 89 | 16 | Kalel Mullings | TEN | KC | Bench |
| 90 | 16 | Julius Chestnut | TEN | KC | Bench |
| 91 | 16 | Trevor Etienne | CAR | TB | Bench |
| 92 | 16 | Raheim Sanders | CLE | BUF | Bench |
| OUT | -- | Alvin Kamara | NO | NYJ | |
| OUT | -- | Devin Neal | NO | NYJ | |
| OUT | -- | Dylan Sampson | CLE | BUF | |
| QUE | -- | Woody Marks | HOU | LV | |
| QUE | -- | Nick Chubb | HOU | LV | |
| OUT | -- | Bhayshul Tuten | JAX | @DEN | |
| IR-R | -- | Justice Hill | BAL | NE | |
| IR | -- | Bam Knight | ARI | ATL | |
| IR | -- | Trey Benson | ARI | ATL | |
| IR | -- | Jerome Ford | CLE | BUF | |
| IR | -- | Terrell Jennings | NE | @BAL | |
| SUSP | -- | Josh Williams | TB | @CAR |
Week 16 WR Rankings
| Rk | Tr | Wide Receiver | TM | OPP | Week 16 Value |
| 1 | 1 | Jaxon Smith-Njigba | SEA | LAR | DONE-TNF |
| 2 | 1 | Mike Evans | TB | @CAR | Elite WR1 |
| 3 | 2 | Ja'Marr Chase | CIN | @MIA | Elite WR1 |
| 4 | 2 | A.J. Brown | PHI | @WAS | Elite WR1 |
| 5 | 2 | Amon-Ra St. Brown | DET | PIT | Elite WR1 |
| 6 | 2 | Puka Nacua | LAR | @SEA | DONE-TNF |
| 7 | 3 | DK Metcalf | PIT | @DET | WR1 |
| 8 | 3 | DJ Moore | CHI | GB | WR1 |
| 9 | 3 | Christian Watson | GB | @CHI | INJ-QUE |
| 10 | 4 | Nico Collins | HOU | LV | WR1/WR2 |
| 11 | 4 | Chris Olave | NO | NYJ | WR1/WR2 |
| 12 | 4 | Wan'Dale Robinson | NYG | MIN | WR1/WR2 |
| 13 | 4 | Jameson Williams | DET | PIT | WR1/WR2 |
| 14 | 4 | Terry McLaurin | WAS | PHI | WR1/WR2 |
| 15 | 5 | CeeDee Lamb | DAL | LAC | Strong WR2 |
| 16 | 5 | George Pickens | DAL | LAC | Strong WR2 |
| 17 | 3 | Michael Wilson | ARI | ATL | WR1Strong WR2 |
| 18 | 6 | Jauan Jennings | SF | @IND | Strong WR2 |
| 19 | 6 | Jakobi Meyers | JAX | @DEN | WR2 |
| 20 | 6 | Justin Jefferson | MIN | @NYG | WR2 |
| 21 | 6 | Courtland Sutton | DEN | JAX | WR2 |
| 22 | 6 | DeVonta Smith | PHI | @WAS | WR2 |
| 23 | 7 | Marvin Harrison | ARI | ATL | WR2 |
| 24 | 7 | Xavier Worthy | KC | @TEN | WR2 |
| 25 | 7 | Chris Godwin | TB | @CAR | WR2 |
| 26 | 7 | Brian Thomas | JAX | @DEN | WR2 |
| 27 | 7 | Jayden Reed | GB | @CHI | WR2 |
| 28 | 7 | Troy Franklin | DEN | JAX | WR2 |
| 29 | 8 | Keenan Allen | LAC | @DAL | WR2/WR3 |
| 30 | 8 | Adonai Mitchell | NYJ | @NO | WR2/WR3 |
| 31 | 8 | Zay Flowers | BAL | NE | WR2/WR3 |
| 32 | 9 | Ladd McConkey | LAC | @DAL | Strong WR3 |
| 33 | 9 | Ricky Pearsall | SF | @IND | Strong WR3 |
| 34 | 9 | Emeka Egbuka | TB | @CAR | Strong WR3 |
| 35 | 9 | Jordan Addison | MIN | @NYG | Strong WR3 |
| 36 | 9 | Tetairoa McMillan | CAR | TB | Strong WR3 |
| 37 | 10 | Jerry Jeudy | CLE | BUF | WR3 |
| 38 | 10 | Jalen Coker | CAR | TB | WR3 |
| 39 | 10 | Khalil Shakir | BUF | @CLE | WR3 |
| 40 | 10 | Jaylen Waddle | MIA | CIN | WR3 |
| 41 | 11 | Jalen Nailor | MIN | @NYG | WR3/Flex |
| 42 | 11 | John Metchie | NYJ | @NO | WR3/Flex |
| 43 | 11 | Josh Downs | IND | SF | WR3/Flex |
| 44 | 11 | Michael Pittman | IND | SF | WR3/Flex |
| 45 | 12 | Jalen McMillan | TB | @CAR | Flex |
| 46 | 12 | Chimere Dike | TEN | KC | Flex |
| 47 | 12 | Michael Bandy | DEN | JAX | Flex |
| 48 | 12 | Christian Kirk | HOU | LV | Flex |
| 49 | 12 | Devaughn Vele | NO | NYJ | Flex |
| 50 | 12 | Alec Pierce | IND | SF | Flex |
| 51 | 13 | Cooper Kupp | SEA | LAR | DONE-TNF |
| 52 | 13 | Elic Ayomanor | TEN | KC | Flex |
| 53 | 13 | David Sills | ATL | @ARI | Flex |
| 54 | 13 | Stefon Diggs | NE | @BAL | Flex |
| 55 | 13 | Jayden Higgins | HOU | LV | Flex |
| 56 | 13 | Darius Slayton | NYG | MIN | Flex |
| 57 | 13 | Deebo Samuel | WAS | PHI | Flex |
| 58 | 14 | Marquez Valdes-Scantling | PIT | @DET | Flex/Bench |
| 59 | 14 | Rashid Shaheed | SEA | LAR | DONE-TNF |
| 60 | 14 | Olamide Zaccheaus | CHI | GB | Flex/Bench |
| 61 | 14 | Parker Washington | JAX | @DEN | Flex/Bench |
| 62 | 14 | Dontayvion Wicks | GB | @CHI | INJ-QUE |
| 63 | 14 | Romeo Doubs | GB | @CHI | Flex/Bench |
| 64 | 14 | Pat Bryant | DEN | JAX | Flex/Bench |
| 65 | 14 | Darnell Mooney | ATL | @ARI | Flex/Bench |
| 66 | 14 | Kyle Williams | NE | @BAL | Flex/Bench |
| 67 | 14 | Ryan Flournoy | DAL | LAC | Flex/Bench |
| 68 | 15 | Hollywood Brown | KC | @TEN | Bench |
| 69 | 15 | JuJu Smith-Schuster | KC | @TEN | Bench |
| 70 | 15 | Tre' Harris | LAC | @DAL | Bench |
| 71 | 15 | Tim Patrick | JAX | @DEN | Bench |
| 72 | 15 | Greg Dortch | ARI | ATL | Bench |
| 73 | 15 | Mack Hollins | NE | @BAL | Bench |
| 74 | 15 | Mitchell Tinsley | CIN | @MIA | Bench |
| 75 | 15 | Andrei Iosivas | CIN | @MIA | Bench |
| 76 | 15 | Kevin Austin | NO | NYJ | Bench |
| 77 | 15 | Tre Tucker | LV | @HOU | Bench |
| 78 | 15 | Joshua Palmer | BUF | @CLE | Bench |
| 79 | 15 | Jack Bech | LV | @HOU | Bench |
| 80 | 15 | Tyler Lockett | LV | @HOU | Bench |
| 81 | 15 | Isaiah Williams | NYJ | @NO | Bench |
| 82 | 15 | Rashod Bateman | BAL | NE | Bench |
| 83 | 15 | Tom Kennedy | DET | PIT | Bench |
| 84 | 15 | Malik Washington | MIA | CIN | Bench |
| 85 | 16 | Marvin Mims | DEN | JAX | Bench |
| 86 | 16 | Keon Coleman | BUF | @CLE | Bench |
| 87 | 16 | Isaiah Hodgins | NYG | MIN | Bench |
| 88 | 16 | Lil'Jordan Humphrey | DEN | JAX | Bench |
| 89 | 16 | Kayshon Boutte | NE | @BAL | Bench |
| 90 | 16 | Matthew Golden | GB | @CHI | Bench |
| 91 | 16 | Isaiah Bond | CLE | BUF | Bench |
| 92 | 16 | Tez Johnson | TB | @CAR | Bench |
| 93 | 16 | DeMario Douglas | NE | @BAL | Bench |
| 94 | 16 | KaVontae Turpin | DAL | LAC | Bench |
| 95 | 16 | Xavier Smith | LAR | @SEA | DONE-TNF |
| 96 | 16 | Isaac TeSlaa | DET | PIT | Bench |
| 97 | 16 | Bo Melton | GB | @CHI | Bench |
| 98 | 16 | KeAndre Lambert-Smith | LAC | @DAL | Bench |
| 99 | 16 | Shedrick Jackson | LV | @HOU | Bench |
| 100 | 17 | Jalen Brooks | ARI | ATL | Bench |
| 101 | 17 | Xavier Legette | CAR | TB | Bench |
| 102 | 17 | Mason Tipton | NO | NYJ | Bench |
| 103 | 17 | Van Jefferson | TEN | KC | Bench |
| 104 | 17 | Dylan Drummond | ATL | @ARI | Bench |
| 105 | 17 | Xavier Restrepo | TEN | KC | Bench |
| 106 | 17 | Savion Williams | GB | @CHI | Bench |
| 107 | 17 | Darius Cooper | PHI | @WAS | Bench |
| 108 | 17 | Devin Duvernay | CHI | GB | Bench |
| 109 | 17 | Gage Larvadain | CLE | BUF | Bench |
| 110 | 17 | Deven Thompkins | ATL | @ARI | Bench |
| 111 | 17 | DeAndre Hopkins | BAL | NE | Bench |
| 112 | 17 | Calvin Austin | PIT | @DET | Bench |
| 113 | 17 | Xavier Hutchinson | HOU | LV | Bench |
| 114 | 17 | Demarcus Robinson | SF | @IND | Bench |
| 115 | 17 | Tyrell Shavers | BUF | @CLE | Bench |
| 116 | 17 | Cedrick Wilson | MIA | CIN | Bench |
| 117 | 17 | Cody White | SEA | LAR | DONE-TNF |
| 118 | 17 | Treylon Burks | WAS | PHI | Bench |
| 119 | 17 | Sterling Shepard | TB | @CAR | Bench |
| 120 | 17 | James Proche | TEN | KC | Bench |
| 121 | 17 | Dante Pettis | NO | NYJ | Bench |
| 122 | 17 | Dont'e Thornton | LV | @HOU | Bench |
| 123 | 17 | Tai Felton | MIN | @NYG | Bench |
| 124 | 17 | Devontez Walker | BAL | NE | Bench |
| 125 | 17 | Konata Mumpfield | LAR | @SEA | DONE-TNF |
| 126 | 17 | Kendrick Bourne | SF | @IND | Bench |
| 127 | 17 | Jimmy Horn | CAR | TB | Bench |
| 128 | 17 | Ben Skowronek | PIT | @DET | Bench |
| 129 | 17 | Jonathan Mingo | DAL | LAC | Bench |
| 130 | 17 | Jaylin Noel | HOU | LV | Bench |
| 131 | 17 | Adam Thielen | PIT | @DET | Bench |
| 132 | 17 | Cedric Tillman | CLE | BUF | Bench |
| 133 | 17 | Malachi Corley | CLE | BUF | Bench |
| 134 | 17 | Kalif Raymond | DET | PIT | Bench |
| 135 | 17 | Jordan Whittington | LAR | @SEA | DONE-TNF |
| 136 | 18 | Allen Lazard | FA | Bench | |
| 137 | 18 | Andre Baccellia | ARI | ATL | Bench |
| 138 | 18 | Xavier Gipson | PHI | @WAS | Bench |
| 139 | 18 | Jahan Dotson | PHI | @WAS | Bench |
| 140 | 18 | Brandin Cooks | BUF | @CLE | Bench |
| 141 | 18 | Xavier Weaver | ARI | ATL | Bench |
| 142 | 18 | Gabe Davis | BUF | @CLE | Bench |
| 143 | 18 | Roman Wilson | PIT | @DET | Bench |
| 144 | 18 | Trent Sherfield | ARI | ATL | Bench |
| 145 | 18 | Kameron Johnson | TB | @CAR | Bench |
| 146 | 18 | Austin Trammell | JAX | @DEN | Bench |
| 147 | 18 | Dyami Brown | JAX | @DEN | Bench |
| 148 | 18 | Malik Heath | GB | @CHI | Bench |
| 149 | 18 | Charlie Jones | CIN | @MIA | Bench |
| 150 | 18 | Arian Smith | NYJ | @NO | Bench |
| 151 | 18 | Tylan Wallace | BAL | NE | Bench |
| 152 | 18 | Jalin Hyatt | NYG | MIN | Bench |
| 153 | 18 | Jaylin Lane | WAS | PHI | Bench |
| 154 | 18 | Nick Westbrook-Ikhine | MIA | CIN | Bench |
| 155 | 18 | Elijah Moore | DEN | JAX | Bench |
| 156 | 18 | Tyler Johnson | NYJ | @NO | Bench |
| 157 | 18 | Jalen Tolbert | DAL | LAC | Bench |
| 158 | 18 | Chris Moore | WAS | PHI | Bench |
| OUT | -- | Rashee Rice | KC | @TEN | |
| OUT | -- | Luther Burden | CHI | GB | |
| OUT | -- | Rome Odunze | CHI | GB | |
| INACTIVE | -- | Davante Adams | LAR | @SEA | DONE-TNF |
| QUE | -- | Drake London | ATL | @ARI | |
| QUE | -- | Tee Higgins | CIN | @MIA | |
| QUE | -- | Quentin Johnston | LAC | @DAL | |
| OUT | -- | Tyquan Thornton | KC | @TEN | |
| INJ | -- | Anthony Gould | IND | SF | |
| IR-R | -- | Josh Reynolds | NYJ | @NO | |
| IR-R | -- | Tutu Atwell | LAR | @SEA | DONE-TNF |
| IR-R | -- | Tory Horton | SEA | LAR | DONE-TNF |
| IR-R | -- | Ashton Dulin | IND | SF | |
| IR | -- | Garrett Wilson | NYJ | @NO | |
| IR | -- | Calvin Ridley | TEN | KC | |
| IR | -- | Noah Brown | WAS | PHI | |
| RES | -- | Brandon Aiyuk | SF | @IND |
Week 16 TE Rankings
| Rk | Tr | Name | TM | OPP | Week 16 Value |
| 1 | 1 | Trey McBride | ARI | ATL | Elite TE1 |
| 2 | 2 | Kyle Pitts | ATL | @ARI | Elite TE1 |
| 3 | 2 | George Kittle | SF | @IND | Elite TE1 |
| 4 | 2 | Harold Fannin | CLE | BUF | Elite TE1 |
| 5 | 3 | Travis Kelce | KC | @TEN | TE1 |
| 6 | 3 | Tyler Warren | IND | SF | TE1 |
| 7 | 3 | Brock Bowers | LV | @HOU | TE1 |
| 8 | 4 | Brenton Strange | JAX | @DEN | Top TE Streamer |
| 9 | 4 | Darren Waller | MIA | CIN | Top TE Streamer |
| 10 | 4 | Dallas Goedert | PHI | @WAS | Top TE Streamer |
| 11 | 4 | Jake Ferguson | DAL | LAC | Top TE Streamer |
| 12 | 4 | Colby Parkinson | LAR | @SEA | DONE-TNF |
| 13 | 5 | Oronde Gadsden | LAC | @DAL | TE Streamer |
| 14 | 5 | Isaiah Likely | BAL | NE | TE Streamer |
| 15 | 5 | T.J. Hockenson | MIN | @NYG | TE Streamer |
| 16 | 5 | Dalton Schultz | HOU | LV | TE Streamer |
| 17 | 5 | Hunter Henry | NE | @BAL | TE Streamer |
| 18 | 6 | Dawson Knox | BUF | @CLE | Deep TE Bonus Sleeper |
| 19 | 6 | Colston Loveland | CHI | GB | Deep TE Bonus Sleeper |
| 20 | 6 | Dalton Kincaid | BUF | @CLE | Deep TE Bonus Sleeper |
| 21 | 6 | Ben Sinnott | WAS | PHI | Deep TE Bonus Sleeper |
| 22 | 7 | Luke Musgrave | GB | @CHI | Deep TE Bonus Sleeper |
| 23 | 7 | Evan Engram | DEN | JAX | Deep TE Bonus Sleeper |
| 24 | 7 | Mark Andrews | BAL | NE | Deep TE Bonus Sleeper |
| INJ | 7 | Cade Otton | TB | @CAR | Deep TE Bonus Sleeper |
| 25 | 7 | Theo Johnson | NYG | MIN | Deep TE Bonus Sleeper |
| 26 | 8 | Gunnar Helm | TEN | KC | Bench |
| 27 | 8 | Mike Gesicki | CIN | @MIA | Bench |
| 28 | 8 | AJ Barner | SEA | LAR | DONE-TNF |
| 29 | 8 | Juwan Johnson | NO | NYJ | Bench |
| 30 | 9 | Greg Dulcich | MIA | CIN | Bench |
| 31 | 9 | Noah Gray | KC | @TEN | Bench |
| 32 | 9 | Drew Ogletree | IND | SF | Bench |
| 33 | 9 | Luke Schoonmaker | DAL | LAC | Bench |
| 34 | 9 | Will Dissly | LAC | @DAL | Bench |
| 35 | 9 | Chig Okonkwo | TEN | KC | Bench |
| 36 | 9 | Michael Mayer | LV | @HOU | Bench |
| 37 | 9 | Ian Thomas | LV | @HOU | Bench |
| 38 | 10 | Adam Trautman | DEN | JAX | Bench |
| 39 | 10 | Josh Oliver | MIN | @NYG | Bench |
| 40 | 10 | Pat Freiermuth | PIT | @DET | Bench |
| 41 | 10 | Hunter Long | JAX | @DEN | Bench |
| 42 | 10 | Austin Hooper | NE | @BAL | Bench |
| 43 | 10 | Cole Kmet | CHI | GB | Bench |
| 44 | 11 | Brevyn Spann-Ford | DAL | LAC | Bench |
| 45 | 11 | Charlie Woerner | ATL | @ARI | Bench |
| 46 | 11 | Tanner Hudson | CIN | @MIA | Bench |
| 47 | 11 | Devin Culp | TB | @CAR | Bench |
| 48 | 11 | Darnell Washington | PIT | @DET | Bench |
| 49 | 11 | Quintin Morris | JAX | @DEN | Bench |
| 50 | 11 | Jackson Hawes | BUF | @CLE | Bench |
| 51 | 11 | Davis Allen | LAR | @SEA | DONE-TNF |
| 52 | 11 | Jeremy Ruckert | NYJ | @NO | Bench |
| 53 | 11 | Daniel Bellinger | NYG | MIN | Bench |
| 54 | 12 | Tommy Tremble | CAR | TB | Bench |
| 55 | 12 | Mitchell Evans | CAR | TB | Bench |
| 56 | 12 | Ross Dwelley | DET | PIT | Bench |
| 57 | 12 | John FitzPatrick | GB | @CHI | Bench |
| 58 | 12 | Pharaoh Brown | ARI | ATL | Bench |
| 59 | 12 | Jonnu Smith | PIT | @DET | Bench |
| 60 | 12 | Cade Stover | HOU | LV | Bench |
| 61 | 13 | Mo Alie-Cox | IND | SF | Bench |
| 62 | 13 | Ja'Tavion Sanders | CAR | TB | Bench |
| 63 | 13 | Terrance Ferguson | LAR | @SEA | DONE-TNF |
| 64 | 13 | Jared Wiley | KC | @TEN | Bench |
| 65 | 13 | John Bates | WAS | PHI | Bench |
| 66 | 13 | Drew Sample | CIN | @MIA | Bench |
| 67 | 13 | Johnny Mundt | JAX | @DEN | Bench |
| 68 | 13 | Elijah Higgins | ARI | ATL | Bench |
| 69 | 13 | Taysom Hill | NO | NYJ | Bench |
| 70 | 13 | Foster Moreau | NO | NYJ | Bench |
| 71 | 14 | Julian Hill | MIA | CIN | Bench |
| 72 | 14 | Grant Calcaterra | PHI | @WAS | Bench |
| 73 | 14 | Anthony Firkser | DET | PIT | Bench |
| 74 | 14 | Colson Yankoff | WAS | PHI | Bench |
| 75 | 14 | David Martin-Robinson | TEN | KC | Bench |
| 76 | 14 | Charlie Kolar | BAL | NE | Bench |
| 77 | 15 | Luke Farrell | SF | @IND | Bench |
| 78 | 15 | Josh Whyle | GB | @CHI | Bench |
| 79 | 15 | Josiah Deguara | ARI | ATL | Bench |
| 80 | 15 | Nate Adkins | DEN | JAX | Bench |
| 81 | 15 | Blake Whiteheart | CLE | BUF | Bench |
| 82 | 15 | Eric Saubert | SEA | LAR | DONE-TNF |
| 83 | 15 | Jack Stoll | NO | NYJ | Bench |
| 84 | 15 | Payne Durham | TB | @CAR | Bench |
| 85 | 15 | Ben Sims | MIN | @NYG | Bench |
| 86 | 15 | Stone Smartt | NYJ | @NO | Bench |
| 87 | 15 | Durham Smythe | CHI | GB | Bench |
| OUT | -- | Mason Taylor | NYJ | @NO | |
| INJ | -- | Brock Wright | DET | PIT | |
| OUT | -- | David Njoku | CLE | BUF | |
| OUT | -- | Noah Fant | CIN | @MIA | |
| IR-R | -- | Sam LaPorta | DET | PIT | |
| IR-R | -- | Harrison Bryant | HOU | LV | |
| IR-R | -- | Tyler Higbee | LAR | @SEA | DONE-TNF |
| IR-R | -- | Elijah Arroyo | SEA | LAR | DONE-TNF |
| IR | -- | Zach Ertz | WAS | PHI |
Week 16 D/ST Rankings
| Rk | Team Defense | OPP | Chg |
| 1 | Houston Texans | LV | |
| 2 | San Francisco 49ers | @IND | |
| 3 | Philadelphia Eagles | @WAS | |
| 4 | Denver Broncos | JAX | |
| 5 | Buffalo Bills | @CLE | ⬆️ 7 |
| 6 | Green Bay Packers | @CHI | |
| 7 | Chicago Bears | GB | |
| 8 | Seattle Seahawks | LAR | TNF |
| 9 | Indianapolis Colts | SF | ⬆️ 1 |
| 10 | Jacksonville Jaguars | @DEN | |
| 11 | Kansas City Chiefs | @TEN | ⬇️ 2 |
| 12 | Los Angeles Rams | @SEA | TNF |
| 13 | Detroit Lions | PIT | ⬆️ 2 |
| 14 | Tampa Bay Buccaneers | @CAR | |
| 15 | New Orleans Saints | NYJ | |
| 16 | Carolina Panthers | TB | |
| 17 | Atlanta Falcons | @ARI | ⬇️ 2 |
| 18 | Cleveland Browns | BUF | |
| 19 | Arizona Cardinals | ATL | |
| 20 | Baltimore Ravens | NE | |
| 21 | Los Angeles Chargers | @DAL | |
| 22 | Pittsburgh Steelers | @DET | |
| 23 | Minnesota Vikings | @NYG | |
| 24 | New York Jets | @NO | |
| 25 | New England Patriots | @BAL | |
| 26 | New York Giants | MIN | |
| 27 | Dallas Cowboys | LAC | |
| 28 | Miami Dolphins | CIN | |
| 29 | Tennessee Titans | KC | |
| 30 | Las Vegas Raiders | @HOU | |
| 31 | Washington Commanders | PHI | |
| 32 | Cincinnati Bengals | @MIA |
Week 16 PK Rankings
| Rk | Kicker | TM | OPP | Chg |
| 1 | Cameron Dicker | LAC | @DAL | |
| 2 | Brandon Aubrey | DAL | LAC | |
| 3 | Jake Bates | DET | PIT | ⬆️ 2 |
| 4 | Jake Elliott | PHI | @WAS | |
| 5 | Harrison Mevis | LAR | @SEA | TNF |
| 6 | Wil Lutz | DEN | JAX | ⬆️ 2 |
| 7 | Ka'imi Fairbairn | HOU | LV | |
| 8 | Jason Myers | SEA | LAR | TNF |
| 9 | Chase McLaughlin | TB | @CAR | |
| 10 | Tyler Loop | BAL | NE | |
| 11 | Matt Prater | BUF | @CLE | |
| 12 | Chris Boswell | PIT | @DET | |
| 13 | Will Reichard | MIN | @NYG | |
| 14 | Evan McPherson | CIN | @MIA | ⬇️ 2 |
| 15 | Cam Little | JAX | @DEN | |
| 16 | Andy Borregales | NE | @BAL | |
| 17 | Brandon McManus | GB | @CHI | ⬆️ 1 |
| 18 | Cairo Santos | CHI | GB | |
| 19 | Harrison Butker | KC | @TEN | ⬇️ 2 |
| 20 | Chad Ryland | ARI | ATL | |
| 21 | Riley Patterson | MIA | CIN | |
| 22 | Joey Slye | TEN | KC | |
| 23 | Eddy Pineiro | SF | @IND | |
| 24 | Ryan Fitzgerald | CAR | TB | |
| 25 | Nick Folk | NYJ | @NO | |
| 26 | Zane Gonzalez | ATL | @ARI | |
| 27 | Blake Grupe | IND | SF | |
| 28 | Charlie Smyth | NO | NYJ | |
| 29 | Daniel Carlson | LV | @HOU | |
| 30 | Andre Szmyt | CLE | BUF | |
| 31 | Jake Moody | WAS | PHI | |
| 32 | Younghoe Koo | NYG | MIN |
Week 16 Flex Half-PPR Rankings
| Rk | Player Name | TM | POS | OPP | Chg |
| 1 | De'Von Achane | MIA | RB1 | CIN | |
| 2 | Puka Nacua | LAR | WR1 | @SEA | TNF |
| 3 | Jahmyr Gibbs | DET | RB2 | PIT | |
| 4 | Jaxon Smith-Njigba | SEA | WR2 | LAR | TNF |
| 5 | Christian McCaffrey | SF | RB3 | @IND | |
| 6 | Ja'Marr Chase | CIN | WR3 | @MIA | |
| 7 | Amon-Ra St. Brown | DET | WR4 | PIT | |
| 8 | Bijan Robinson | ATL | RB4 | @ARI | |
| 9 | Jonathan Taylor | IND | RB5 | SF | |
| 10 | James Cook III | BUF | RB6 | @CLE | |
| 11 | Bucky Irving | TB | RB7 | @CAR | |
| 12 | Ladd McConkey | LAC | WR5 | @DAL | |
| 13 | CeeDee Lamb | DAL | WR6 | LAC | |
| 14 | Saquon Barkley | PHI | RB8 | @WAS | |
| 15 | Jaylen Waddle | MIA | WR7 | CIN | |
| 16 | Nico Collins | HOU | WR8 | LV | |
| 17 | Jameson Williams | DET | WR9 | PIT | |
| 18 | Javonte Williams | DAL | RB9 | LAC | |
| 19 | Trey McBride | ARI | TE1 | ATL | ⬆️ 2 |
| 20 | RJ Harvey | DEN | RB10 | JAX | |
| 21 | Kyren Williams | LAR | RB11 | @SEA | TNF |
| 22 | Omarion Hampton | LAC | RB12 | @DAL | |
| 23 | Mike Evans | TB | WR10 | @CAR | |
| 24 | Derrick Henry | BAL | RB13 | NE | |
| 25 | Travis Etienne Jr. | JAX | RB14 | @DEN | |
| 26 | Brock Bowers | LV | TE2 | @HOU | ⬇️ 1 |
| 27 | Xavier Worthy | KC | WR11 | @TEN | ⬆️ 10 |
| 28 | Jaylen Warren | PIT | RB15 | @DET | |
| 29 | Ashton Jeanty | LV | RB16 | @HOU | |
| 30 | D'Andre Swift | CHI | RB17 | GB | |
| 31 | George Pickens | DAL | WR12 | LAC | |
| 32 | Josh Jacobs | GB | RB18 | @CHI | |
| 33 | Rico Dowdle | CAR | RB19 | TB | |
| 34 | Terry McLaurin | WAS | WR13 | PHI | |
| 35 | Tyler Warren | IND | TE3 | SF | |
| 36 | Quinshon Judkins | CLE | RB20 | BUF | |
| 37 | TreVeyon Henderson | NE | RB21 | @BAL | |
| 38 | Chris Olave | NO | WR14 | NYJ | |
| 39 | Courtland Sutton | DEN | WR15 | JAX | |
| 40 | Tetairoa McMillan | CAR | WR16 | TB | |
| 41 | DK Metcalf | PIT | WR17 | @DET | |
| 42 | Michael Pittman Jr. | IND | WR18 | SF | |
| 43 | A.J. Brown | PHI | WR19 | @WAS | |
| 44 | Chase Brown | CIN | RB22 | @MIA | |
| 45 | Michael Wilson | ARI | WR20 | ATL | |
| 46 | David Montgomery | DET | RB23 | PIT | |
| 47 | Kimani Vidal | LAC | RB24 | @DAL | |
| 48 | Jalen Coker | CAR | WR21 | TB | |
| 49 | Audric Estime | NO | RB25 | NYJ | |
| 50 | George Kittle | SF | TE4 | @IND | |
| 51 | Justin Jefferson | MIN | WR22 | @NYG | |
| 52 | Woody Marks | HOU | RB26 | LV | |
| 53 | Breece Hall | NYJ | RB27 | @NO | |
| 54 | Kyle Pitts Sr. | ATL | TE5 | @ARI | |
| 55 | Christian Watson | GB | WR23 | @CHI | |
| 56 | Khalil Shakir | BUF | WR24 | @CLE | |
| 57 | Emeka Egbuka | TB | WR25 | @CAR | |
| 58 | Zach Charbonnet | SEA | RB28 | LAR | TNF |
| 59 | Brian Thomas Jr. | JAX | WR26 | @DEN | |
| 60 | DeVonta Smith | PHI | WR27 | @WAS | |
| 61 | Brenton Strange | JAX | TE6 | @DEN | |
| 62 | Kenneth Walker III | SEA | RB29 | LAR | TNF |
| 63 | Dalton Kincaid | BUF | TE7 | @CLE | |
| 64 | Jakobi Meyers | JAX | WR28 | @DEN | |
| 65 | Dallas Goedert | PHI | TE8 | @WAS | |
| 66 | Wan'Dale Robinson | NYG | WR29 | MIN | |
| 67 | Rhamondre Stevenson | NE | RB30 | @BAL | |
| 68 | Oronde Gadsden | LAC | TE9 | @DAL | |
| 69 | Chris Godwin | TB | WR30 | @CAR | |
| 70 | Aaron Jones | MIN | RB31 | @NYG | |
| 71 | Jake Ferguson | DAL | TE10 | LAC | |
| 72 | Jerry Jeudy | CLE | WR31 | BUF | |
| 73 | Quentin Johnston | LAC | WR32 | @DAL | |
| 74 | Deebo Samuel | WAS | WR33 | PHI | |
| 75 | Bam Knight | ARI | RB32 | ATL | |
| 76 | Chuba Hubbard | CAR | RB33 | TB | |
| 77 | Darius Slayton | NYG | WR34 | MIN | |
| 78 | Stefon DIggs | NE | WR35 | @BAL | |
| 79 | Zay Flowers | BAL | WR36 | NE | |
| 80 | Hunter Henry | NE | TE11 | @BAL | |
| 81 | Andrei Iosivas | CIN | WR37 | @MIA | |
| 82 | Ricky Pearsall | SF | WR38 | @IND | |
| 83 | Keenan Allen | LAC | WR39 | @DAL | |
| 84 | Juwan Johnson | NO | TE12 | NYJ | |
| 85 | Blake Corum | LAR | RB34 | @SEA | TNF |
| 86 | DJ Moore | CHI | WR40 | GB | |
| 87 | Jordan Whittington | LAR | WR41 | @SEA | TNF |
| 88 | Jauan Jennings | SF | WR42 | @IND | |
| 89 | Kenneth Gainwell | PIT | RB35 | @DET | ⬆️ 1 |
| 90 | Jordan Addison | MIN | WR43 | @NYG | |
| 91 | Tyler Allgeier | ATL | RB36 | @ARI | |
| 92 | Jordan Mason | MIN | RB37 | @NYG | |
| 93 | Bhayshul Tuten | JAX | RB38 | @DEN | |
| 94 | Alec Pierce | IND | WR44 | SF | |
| 95 | Tre Tucker | LV | WR45 | @HOU | |
| 96 | Tony Pollard | TEN | RB39 | KC | |
| 97 | Kareem Hunt | KC | RB40 | @TEN | ⬆️ 1 |
| 98 | Harold Fannin Jr. | CLE | TE13 | BUF | |
| 99 | Dalton Schultz | HOU | TE14 | LV | |
| 100 | Isaiah Likely | BAL | TE15 | NE | |
| 101 | Romeo Doubs | GB | WR46 | @CHI | ⬆️ 1 |
| 102 | Kyle Monangai | CHI | RB41 | GB | |
| 103 | Darnell Mooney | ATL | WR47 | @ARI | |
| 104 | Jayden Higgins | HOU | WR48 | LV | |
| 105 | Kayshon Boutte | NE | WR49 | @BAL | ⬆️ 4 |
| 106 | Tyjae Spears | TEN | RB42 | KC | |
| 107 | Ollie Gordon II | MIA | RB43 | CIN | |
| 108 | Rachaad White | TB | RB44 | @CAR | |
| 109 | Emanuel Wilson | GB | RB45 | @CHI | |
| 110 | Keon Coleman | BUF | WR50 | @CLE | |
| 111 | Evan Engram | DEN | TE16 | JAX | |
| 112 | Ryan Flournoy | DAL | WR51 | LAC | |
| 113 | Jalen Nailor | MIN | WR52 | @NYG | |
| 114 | Chimere Dike | TEN | WR53 | KC | |
| 115 | Troy Franklin | DEN | WR54 | JAX | |
| 116 | Mark Andrews | BAL | TE17 | NE | |
| 117 | Jayden Reed | GB | WR55 | @CHI | |
| 118 | Cooper Kupp | SEA | WR56 | LAR | TNF |
| 119 | Isiah Pacheco | KC | RB46 | @TEN | ⬇️ 2 |
| 120 | Devin Singletary | NYG | RB47 | MIN | |
| 121 | Cedric Tillman | CLE | WR57 | BUF | |
| 122 | Marquise Brown | KC | WR58 | @TEN | |
| 123 | Luther Burden III | CHI | WR59 | GB | |
| 124 | Devaughn Vele | NO | WR60 | NYJ | |
| 125 | Travis Kelce | KC | TE18 | @TEN | |
| 126 | Adondai Mitchell | NYJ | WR61 | @NO | |
| 127 | Jaylen Wright | MIA | RB48 | CIN | |
| 128 | Tyrone Tracy Jr. | NYG | RB49 | MIN | ⬆️ 1 |
| 129 | AJ Barner | SEA | TE19 | LAR | TNF |
| 130 | Marvin Mims | DEN | WR62 | JAX | |
| 131 | Isaac TeSlaa | DET | WR63 | PIT | |
| 132 | T.J. Hockenson | MIN | TE20 | @NYG | |
| 133 | David Njoku | CLE | TE21 | BUF | |
| 134 | Chris Rodriguez Jr. | WAS | RB50 | PHI | |
| 135 | Darren Waller | MIA | TE22 | CIN | |
| 136 | Jaleel McLaughlin | DEN | RB51 | JAX | |
| 137 | Theo Johnson | NYG | TE23 | MIN | |
| 138 | Xavier Legette | CAR | WR64 | TB | ⬇️ 4 |
| 139 | Josh Downs | IND | WR65 | SF | |
| 140 | Jacory-Croskey Merritt | WAS | RB52 | PHI | |
| 141 | Gunnar Helm | TEN | TE24 | KC | |
| 142 | Olaminde Zaccheaus | CHI | WR66 | GB | ⬆️ NR |
| 143 | Brian Robinson Jr. | SF | RB53 | @IND | |
| 144 | Elic Ayomanor | TEN | WR67 | KC | |
| 145 | Calvin Austin III | PIT | WR68 | @DET | |
| 146 | Jack Bech | LV | WR69 | @HOU | |
| 147 | Noah Fant | CIN | TE25 | @MIA | |
| 148 | Malik Washington | MIA | WR70 | CIN | |
| 149 | Gabe Davis | BUF | WR71 | @CLE | |
| 150 | Samaje Perine | CIN | RB54 | @MIA |
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