Fantasy Football Defense Rankings Week 1: Who to start, best sleepers, streamers at D/ST

Griffin Missant

Fantasy Football Defense Rankings Week 1: Who to start, best sleepers, streamers at D/ST image

We are back. The NFL season starts Aug. 4 with the Cowboys taking on the reigning Super Bowl champs, the Philadelphia Eagles.

With the NFL season starting, this also means the beginning of fantasy football. Managers face several challenges in Week 1.

There is overall a lack of data to back up any sort of start/sit decision, as well as a sample size of zero games.

Everybody is focused on the offensive players when it comes to fantasy, but defenses can have big weeks, too.

Identifying favorable matchups as the season goes on gets easier. However, here are our Week 1 D/ST rankings, best starts and sleepers, and some matchups to avoid.

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Fantasy Football Defense Rankings Week 1: Who to start, sit at D/ST

RkTeam DefenseOPP
1Denver BroncosTEN
2Arizona Cardinals@NO
3Pittsburgh Steelers@NYJ
4New York JetsPIT
5Washington CommandersNYG
6Chicago BearsMIN
7Minnesota Vikings@CHI
8New England PatriotsLV
9San Francisco 49ers@SEA
10Cincinnati Bengals@CLE
11Tampa Bay Buccaneers@ATL
12Detroit Lions@GB
13Kansas City Chiefsvs. LAC
14Houston Texans@LAR
15Green Bay PackersDET
16Philadelphia EaglesDAL
17Seattle SeahawksSF
18Los Angeles RamsHOU
19Los Angeles ChargersKC
20Miami Dolphins@IND
21Jacksonville JaguarsCAR
22Las Vegas Raiders@NE
23Carolina Panthers@JAX
24Atlanta FalconsTB
25New Orleans SaintsARI
26Cleveland BrownsCIN
27Indianapolis ColtsMIA
28Baltimore Ravens@BUF
29Buffalo BillsBAL
30Tennessee Titans@DEN
31New York Giants@WAS
32Dallas Cowboys@PHI

Go here for our full group of fantasy football weekly rankings.

Who are the best fantasy defenses in Week 1?

The only thing we can base our defensive projections on is last season. We can target poor offenses from last year, but there is a good chance it's still just a guess.

A great thing to look at for Week 1 is who is starting at QB with the opposition. There are a few archetypes to target, such as young or inexperienced QBs. These QBs will be figuring things out, and there are bound to be mistakes along the way.

With this in mind, some of the D/STs that stand out in Week 1 are the Denver Broncos, Arizona Cardinals, and Tampa Bay Buccaneers:

  • The Broncos face Cam Ward, who could be great once he adjusts, but balling Week 1 as a rookie QB is a tough ask. Not to mention, Denver is the best defense in the NFL.
  • The Bucs get Michael Penix, and the Cardinals get Spencer Rattler -- both second-year QBs with not a lot of experience.

Read our Week 1 Start 'Em, Sit 'Em for more D/ST fantasy lineup tips.

Who are the best fantasy defense sleepers in Week 1?

For some sleepers, D/STs that take a QB with more than enough experience, but are in a new system, can provide solid production as well. Just like the younger QBs and rookies, these vets will be working through some mistakes, trying to figure out their new coaches and schemes.

Names like Geno Smith, Aaron Rodgers, and Daniel Jones immediately come to mind. The New England Patriots, who face the Raiders, and the New York Jets, who face the Steelers, could be viable starts in Week 1.

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Defenses to avoid in Week 1 of fantasy football

It's best to avoid those games that could get out of hand offensively. Even if the defenses as a whole are solid units, if each team has dynamic offenses, the game can quickly turn into a shootout.

These matchups include the Kansas City Chiefs vs. the Los Angeles Chargers, Buffalo Bills vs. the Baltimore Ravens, and the Philadelphia Eagles vs. the Dallas Cowboys.

This is not to say these defenses can't provide value throughout the season, but in general, it's best to start a D/ST in fantasy on a week-to-week basis.

Griffin Missant

Griffin Missant joined The Sporting News in 2025 as a fantasy football intern. He graduated from Grand Valley State University, where he covered the Lakers football program. He has also worked for Sleeper and the Fantasy Trade Room. He has played fantasy for over a decade, and has been passionate about fantasy football ever since.