Even in Year 7 of the quarterback's career, the Arizona Cardinals are still looking for their breakthrough season behind Kyler Murray. Part of the reason for that wait, however, has been the team's inability to contend in the NFC West.
Since Murray was drafted by Arizona with the No. 1 pick in the 2019 NFL Draft, the Cardinals have never won their division, finishing in second-place just once. Led by Murray, Arizona has made the playoffs just once, typically an average-to-good team that isn't quite a bottom-feeder, but has consistency issues each season.
One aspect of the Cardinals' NFC West struggles with Murray has been the team's inability to beat the Seattle Seahawks. Murray has rarely beat Seattle in his career, a trend that continued in Week 4 of the 2025 season when Jason Myers' 52-yard field goal sealed a 23-20 Seahawks victory.
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Here's what to know about Murray's career record and stats against the Seahawks.
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Kyler Murray record vs. Seahawks
- 2-9 (.182)
Following a 23-20 Week 4 loss on "Thursday Night Football," Kyler Murray now owns a 2-9 career record against the Seahawks, which dates back to his rookie 2019 season. That includes an active eight-game losing streak.
Murray's only two victories vs. Seattle came early in his career. After losing his first game against the Seahawks as a rookie in September 2019, the Cardinals claimed consecutive wins over Seattle in December 2019, then in October 2020.
An eight-game losing streak for Arizona against Seattle has followed. While Murray was the starting quarterback for the Cardinals in all 11 of those games, the Seahawks have cycled through Russell Wilson (2020-21), Geno Smith (2022-24) and Sam Darnold (2025) at quarterback in that span.
Here's a game-by-game breakdown of Murray's career record vs. Seattle:
| Date | Final Score | Seahawks QB |
| Sept. 29, 2019 | Seahawks 27, Cardinals 10 | Russell Wilson |
| Dec. 22, 2019 | Cardinals 27, Seahawks 13 | Russell Wilson |
| Oct. 25, 2020 | Cardinals 37, Seahawks 34 | Russell Wilson |
| Nov. 19, 2020 | Seahawks 28, Cardinals 21 | Russell Wilson |
| Jan. 9, 2022 | Seahawks 38, Cardinals 30 | Russell Wilson |
| Oct. 16, 2022 | Seahawks 19, Cardinals 9 | Geno Smith |
| Nov. 6, 2022 | Seahawks 31, Cardinals 21 | Geno Smith |
| Jan. 7, 2024 | Seahawks 21, Cardinals 20 | Geno Smith |
| Nov. 24, 2024 | Seahawks 16, Cardinals 6 | Geno Smith |
| Dec. 8, 2024 | Seahawks 30, Cardinals 18 | Geno Smith |
| Sept. 25, 2025 | Seahawks 23, Cardinals 20 | Sam Darnold |
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Kyler Murray career stats vs. Seahawks
- Completions/Attempts: 270/397
- Completion Percentage: 68.0%
- Total Passing Yards: 2,631
- Passing Yards/Game: 239.2
- Passing TDs: 14
- Interceptions: 8
- Rating: 89.7
While Murray's career record against the Seahawks is rough, he hasn't performed terribly on an individual level, tossing 14 touchdown passes against Seattle vs. eight interceptions. But it also has rarely been enough to win, including four career losses to the Seahawks within one score.
Here's a look at Murray's stats in each matchup vs. Seattle:
| Date | Completions-Attempts | Passing Yards | Passing TDs | INTs |
| Sept. 29, 2019 | 22-32 (68.8%) | 241 | 0 | 1 |
| Dec. 22, 2019 | 11-18 (61.1%) | 118 | 1 | 0 |
| Oct. 25, 2020 | 34-48 (70.8%) | 360 | 3 | 1 |
| Nov. 19, 2020 | 29-42 (69.0%) | 269 | 2 | 0 |
| Jan. 9, 2022 | 28-39 (71.8%) | 240 | 1 | 0 |
| Oct. 16, 2022 | 23-37 (62.2%) | 222 | 0 | 1 |
| Nov. 6, 2022 | 25-35 (71.4%) | 175 | 2 | 0 |
| Jan. 7, 2024 | 22-30 (73.3%) | 262 | 1 | 0 |
| Nov. 24, 2024 | 24-37 (64.9%) | 285 | 0 | 1 |
| Dec. 8, 2024 | 25-38 (65.8%) | 259 | 2 | 2 |
| Sept. 25, 2025 | 27-41 (65.9%) | 200 | 2 | 2 |
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Kyler Murray record vs. NFC West
- 8-24 (.250)
There's a reason the Cardinals have struggled to keep up in NFC playoff contention throughout Murray's stint as QB1: they have rarely won divisional games.
In Murray's career, he has an 8-24 record against the Seahawks, San Francisco 49ers and Los Angeles Rams. Two of those wins came against Seattle, four against San Francisco, and two against Los Angeles. Every other time Murray has lined up against a divisional opponent, the Cardinals came out on the wrong side.
Murray owns an overall career record of 38-47-1.