After years of bad blood, fight fans will finally get to see Michael Zerafa in the ring opposite a Tszyu.
Promoters No Limit Boxing confirmed on Wednesday that Nikita Tszyu will face off with Zerafa on Friday, January 16, with the location still to be confirmed.
The fight will be conducted at a 157lb (71.5kg) catchweight.
The pair were originally rumoured to be lining up a bout at the end of November but a recent car accident involving Tszyu contributed to the rescheduling.
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January's fight will end almost half a decade of anticipation, with Zerafa originally scheduled to face Nikita's older brother Tim in 2021.
That bout failed to materialise when Zerafa pulled out at late notice, citing concerns around Covid travel restrictions for him and his team.
The spiteful build-up and controversy surrounding the cancellation contributed to the angst between the parties and Tim Tszyu has remained adamant he wouldn't grant the Victorian another chance at what would be a major pay day.
Nikita, however, is at a different stage of his career and has plenty to gain with a win over the former world title challenger.
The all-action southpaw is undefeated through 11 fights but is yet to face anyone of Zerafa's quality and experience.
A win over Zerafa to kickstart 2026 would rubber stamp the 27-year-old Tszyu's credentials as a genuine world title contender.
While for Zerafa, 33, victory would be sweet satisfaction after years of being painted as the villain of Aussie boxing, while it could even lay the platform for an even bigger bout with Tim Tszyu down the track.
Organisers are expected to confirm the venue and undercard for the pay-per-view event in the coming days.