The Netherlands are in pole position at the top of Group A but they must keep their focus against the already knocked-out hosts Qatar to secure a last-16 spot.
This will be Qatar's final game at their first World Cup, becoming only the second host nation to crash out in the group stages after losing to Ecuador and Senegal.
Only a shock defeat to Felix Sanchez's team could keep the Netherlands out of the Round of 16, but they'll want a convincing victory to secure top spot.
Below are the projected lineups for both teams, based on the latest news leading up to the match.
MORE: How to watch Netherlands vs Qatar
Netherlands vs Qatar confirmed lineups
Louis Van Gaal's Netherlands were stifled against Ecuador in their 1-1 draw and even the half-time introduction of Memphis Depay couldn't give them an edge.
Depay has been struggling with a hamstring issue since September but has appeared from the bench in both his nation's opening World Cup matches.
The Barcelona forward's timely recovery is a major boost for Van Gaal, but the Dutch coach is taking a cautious approach, saying: "We will not take risks with Memphis Depay.
"To become world champions we need him. With Memphis I decide. It all depends on what I see. Memphis has to deliver as well."
Qatar, meanwhile, could look to give some of their fringe players a taste of the World Cup, with their fate already sealed, but is more likely those introductions come from the bench.
Below are the projected starting lineups for both teams ahead of their match at the Al Bayt Stadium on November 29.
Netherlands confirmed starting 11
Marten de Roon comes into the team to partner Frenkie de Jong in midfield, ahead of his Atalanta teammate Teun Koopmeiners.
Van Gaal's other change comes in attack with Depay given the nod over Steven Bergwijn alongside the in form Cody Gakpo.
Netherlands (5-3-2, right to left): 23-Noppert (GK) — 22-Dumfries, 2-Timber, 4-Van Dijk, 5-Ake,17-Blind — 15-De Roon, 21-De Jong, 14-Klaassen — 8-Gakpo, 10-Depay
Qatar confirmed starting 11
Qatar boss Felix Sanchez makes just one change for the final game of their tournament as Abdulaziz Hatem replaces Karim Boudaif in midfield.
Qatar (5-3-2, right to left): 22-Meshaal Barsham (GK) — 2-Pedro Miguel, 17-Ismail Mohammad, 16-Boualem Khoukhi, 3-Abdelkarim Hassan, 14-Homam Ahmed — 10-Hassan Al-Haydos, 6-Abdulaziz Hatem, 23-Assim Madibo — 19-Almoez Ali, 11-Akram Afif
Netherlands vs Qatar World Cup squads
Here are all the name on Netherlands and Qatar's current World Cup squads in Qatar. (Caps correct as of start of Qatar 2022):
Netherlands
| Position | No. | Player | Club | Age | Caps |
|---|---|---|---|---|---|
| GK | 1 | Remko Pasveer | Ajax (NED) | 38 | 2 |
| GK | 22 | Andries Noppert | Heerenveen (NED) | 28 | 0 |
| GK | 13 | Justin Bijlow | Feyenoord (NED) | 24 | 6 |
| DEF | 4 | Virgil van Dijk | Liverpool (ENG) | 31 | 49 |
| DEF | 5 | Nathan Ake | Manchester City (ENG) | 27 | 29 |
| DEF | 26 | Jeremie Frimpong | Bayer Leverkusen (NED) | 21 | 0 |
| DEF | 6 | Stefan de Vrij | Inter (ITA) | 30 | 59 |
| DEF | 17 | Daley Blind | Ajax (NED) | 32 | 94 |
| DEF | 3 | Matthijs de Ligt | Bayern Munich (GER) | 23 | 38 |
| DEF | 16 | Tyrell Malacia | Manchester United (ENG) | 23 | 6 |
| DEF | 2 | Jurrien Timber | Ajax (NED) | 21 | 10 |
| DEF | 22 | Denzel Dumfries | Inter (ITA) | 26 | 37 |
| MID | 21 | Frenkie de Jong | Barcelona (SPA) | 25 | 45 |
| MID | 14 | Davy Klassen | Ajax (NED) | 29 | 35 |
| MID | 25 | Xavi Simons | PSV Eindhoven (NED) | 19 | 0 |
| MID | 11 | Steven Berghuis | Ajax (NED) | 30 | 39 |
| MID | 15 | Marten de Roon | Atalanta (ITA) | 31 | 30 |
| MID | 24 | Kenneth Taylor | Ajax (NED) | 20 | 2 |
| MID | 20 | Teun Koopmeiners | Atalanta (ITA) | 24 | 9 |
| FWD | 10 | Memphis Depay | Barcelona (SPA) | 28 | 81 |
| FWD | 7 | Steven Bergwijn | Ajax (NED) | 25 | 24 |
| FWD | 8 | Cody Gakpo | PSV Eindhoven (NED) | 23 | 9 |
| FWD | 19 | Wout Weghorst | Besiktas (TUR) | 30 | 15 |
| FWD | 18 | Vincent Janssen | Royal Antwerp (BEL) | 28 | 20 |
| FWD | 9 | Luuk de Jong | PSV Eindhoven (NED) | 32 | 38 |
| FWD | 12 | Noa Lang | Club Brugge (BEL) | 23 | 5 |
Qatar
| Position | Player | Club | Age | Caps |
|---|---|---|---|---|
| Goalkeeper | Saad Al-Sheeb | Al Sadd (QAT) | 32 | 80 |
| Goalkeeper | Meshaal Barsham | Al Sadd (QAT) | 24 | 15 |
| Goalkeeper | Yousuf Hassan | Al Gharafa (QAT) | 26 | 9 |
| Defender | Pedro Miguel | Al Sadd (QAT) | 32 | 78 |
| Defender | Musaab Khidir | Al Sadd (QAT) | 29 | 29 |
| Defender | Tarek Salman | Al Sadd (QAT) | 24 | 54 |
| Defender | Bassam Al Rawi | Al Duhail (QAT) | 24 | 51 |
| Defender | Boualem Khoukhi | Al Sadd (QAT) | 32 | 99 |
| Defender | Abdelkarim Hassan | Al Sadd (QAT) | 29 | 120 |
| Defender | Ismaeel Mohammad | Al Duhail (QAT) | 32 | 66 |
| Defender | Homam Ahmed Al Amin | Al Gharafa (QAT) | 23 | 27 |
| Defender | Jassim Jabir | Al Arabi (QAT) | 20 | 0 |
| Midfielder | Ali Asad | Al Sadd (QAT) | 29 | 56 |
| Midfielder | Assim Madibo | Al Duhail (QAT) | 26 | 43 |
| Midfielder | Mohammed Waad | Al Sadd (QAT) | 23 | 20 |
| Midfielder | Salem Al-Hajri | Al Sadd (QAT) | 26 | 23 |
| Midfielder | Mustafa Meshaal Tarek | Al Sadd (QAT) | 21 | 1 |
| Midfielder | Karim Boudiaf | Al Duhail (QAT) | 32 | 108 |
| Midfielder | Abdulaziz Hatim | Al Rayyan (QAT) | 32 | 96 |
| Forward | Naif Al-Hadhrami | Al Rayyan (QAT) | 21 | 1 |
| Forward | Ahmed Alaaeldin | Al Gharafa (QAT) | 29 | 45 |
| Forward | Hassan Al-Haydos | Al Sadd (QAT) | 31 | 160 |
| Forward | Akram Afif | Al Sadd (QAT) | 25 | 83 |
| Forward | Almoez Ali | Al Duhail (QAT) | 26 | 82 |
| Forward | Mohammed Muntari | Al Duhail (QAT) | 28 | 41 |
| Forward | Khalid Muneer | Al Wakrah (QAT) | 24 | 3 |