Two winless teams meet on Sunday Night Football. View the latest Chiefs-Giants betting odds and whether we believe Kansas City can bounce back.
In a matchup few predicted would feature two winless teams, the Kansas City Chiefs and New York Giants are set to collide in a high-stakes Sunday Night Football contest. Both squads enter Week 3 with an 0-2 record, turning this primetime game into a crucial turning point for their respective seasons. The pressure is mounting on both sidelines to right the ship before falling into a nearly insurmountable 0-3 hole.
Patrick Mahomes, who has looked uncharacteristically mortal through two games, is piloting a Chiefs offense that has managed just 19 points per game. He's completed only 58.8% of his passes for 422 yards with a 2-to-1 touchdown-to-interception ratio.
Across the field, the Giants have handed the keys to Russell Wilson, who has put up 618 passing yards on a 60.3% completion rate with three touchdowns and one pick. While Wilson has shown flashes, the Giants' defense has been a significant liability, surrendering over 30 points per game.
This preview will dissect the betting odds and line movement, analyze critical player matchups, and highlight the most valuable player props. We'll cap it off with our official prediction and best bets for a game where one team will finally find the win column and the other will sink further into an early-season crisis.
The Chiefs (0-2) travel to face the Giants (0-2) in a must-win game for both teams. Kickoff is scheduled for 8:20 PM EDT on Sunday, September 21, at MetLife Stadium in East Rutherford, NJ. The game will be broadcast nationally on NBC. The weather forecast calls for a mild evening with a slight chance of drizzle and winds around 10-15 mph, which could play a minor role in the passing and kicking games.
Chiefs vs Giants Betting Odds
| Bet Type | Kansas City Chiefs | New York Giants |
|---|---|---|
| Spread | -6.5 (-110) | +6.5 (-110) |
| Moneyline | -294 | +240 |
| Total Points | Over 45.0 (-110) | Under 45.0 (-110) |
Odds as of September 19, 2025 from BetMGM.
Based on the current moneyline odds, the market implies the Chiefs have a strong chance of securing their first win. After removing the vig, the normalized probabilities suggest the Chiefs have approximately a 71.7% chance to win, while the Giants have a 28.3% chance.
The Chiefs have struggled against the spread, starting the season 0-2 ATS. The Giants are also winless against the spread at 0-2, and have been particularly poor ATS at home, going 3-6 in their last nine games at MetLife Stadium. Get in your pick on the spread using the BetMGM bonus code TSN150.
Odds Movement & Analysis
This NFL betting line has seen significant movement since its opening. The spread opened with the Kansas City Chiefs as 5.5-point favorites and has since been bet up to -6.5, indicating that early money is backing a bounce-back performance from Mahomes and company, despite their 0-2 start. This one-point shift is significant as it moves off the key number of 6 and closer to the touchdown margin.
The game total has also seen a notable jump, opening at 42.5 and climbing to 45.0. This suggests bettors are anticipating either the Chiefs' offense to finally erupt or for the Giants' porous defense (30.5 PPG allowed) to continue its struggles, leading to a higher-scoring affair than initially projected. The Chiefs have gone over the total in three of their last four games, while the Giants' secondary has been repeatedly torched, making an offensive correction for Kansas City plausible.
Key Matchups to Watch
Quarterback vs Pass Defense
Mahomes has been uncharacteristically inefficient, posting a QB rating of just 82.0. However, he faces a Giants pass defense that is bleeding yards, allowing 277.5 per game. New York's secondary has been vulnerable to big plays, which could be the perfect remedy for what ails the Chiefs' air attack.
On the other side, Wilson (92.8 rating) will contend with a hyper-aggressive Chiefs defense that blitzes at the highest rate in the NFL (44%). If the Giants' offensive line can't protect Wilson, it could be a long night for their offense.
Running Game vs Run Defense
Neither team has established a dominant ground game. The Chiefs are averaging 109.5 rushing yards per game, but a large chunk of that comes from Mahomes scrambling. Isiah Pacheco and Kareem Hunt have yet to find consistent running lanes. The Giants have been even less effective, managing a paltry 79.0 rushing yards per game.
Defensively, both units have been average, with the Chiefs allowing 106.0 yards per game and the Giants giving up a concerning 177.5 yards on the ground. The team that can generate some semblance of a rushing attack will gain a significant advantage in controlling the clock and tempo.
Pass Catchers vs Secondary
This matchup heavily favors the receivers. Malik Nabers has been a revelation, and he faces a Chiefs secondary that could be missing key depth pieces. If Wilson has time, Nabers could have a massive day.
For the Chiefs, Marquise Brown has seen high volume but has yet to find the end zone, while Travis Kelce remains the go-to target. They'll be matched up against a Giants secondary that has struggled mightily in coverage and allowed huge gains after the catch.
Offensive Line vs Pass Rush
The game could be won or lost in the trenches. The Giants' offensive line has surrendered five sacks in two games and now faces a defense that loves to send extra rushers. Their ability to give Wilson a clean pocket is paramount.
The Chiefs' offensive line has been solid but not spectacular, allowing four sacks. They'll need to neutralize a Giants pass rush that has generated six sacks this season to give Mahomes the time he needs to find his rhythm.
Chiefs-Giants Player Props: Passing
| Player | Passing Yards | Passing TDs | Completions | INTs |
|---|---|---|---|---|
| Patrick Mahomes (KC) | 230.5 (O -115 | U -115) | 1.5 (O -149 | U +110) | 23.5 (O +100 | U -133) | 0.5 (O -105 | U -125) |
| Russell Wilson (NYG) | 224.5 (O -115 | U -115) | 1.5 (O +160 | U -222) | 20.5 (O -125 | U -105) | 0.5 (O -120 | U -110) |
Mahomes' passing yardage line of 230.5 seems low, even with his early struggles, considering he's facing a defense giving up nearly 280 passing yards per game.
Wilson's line of 224.5 is also intriguing; while he's averaged more this season, the relentless pressure from the Chiefs' defense could disrupt his timing and lead to a lower output. Use the current DraftKings promo code offer to collect a $200 bonus for these SNF player props.
Rushing & Receiving Props
| Player | Rushing Yards | Receiving Yards | Receptions | Anytime TD |
|---|---|---|---|---|
| Isiah Pacheco (KC) | 37.5 (O -133 | U +100) | 8.5 (O -128 | U +100) | 1.5 (O -175 | U +130) | Yes +158 | No -190 |
| Travis Kelce (KC) | N/A | 44.5 (O -115 | U -115) | 4.5 (O -128 | U +100) | Yes +135 | No -165 |
| Marquise Brown (KC) | N/A | 53.5 (O -115 | U -115) | 5.5 (O +110 | U -149) | Yes +152 | No -185 |
| Malik Nabers (NYG) | N/A | 78.5 (O -118 | U -111) | 6.5 (O +100 | U -133) | Yes +135 | No -165 |
| Tyrone Tracy (NYG) | 29.5 (O +100 | U -128) | 14.5 (O +100 | U -128) | 2.5 (O +110 | U -149) | Yes +223 | No -280 |
The receiving yards prop for Nabers at 78.5 is one to watch. He is the undisputed top target for the Giants and has the big-play ability to clear this number on a single catch against a vulnerable Chiefs secondary.
For the Chiefs, Pacheco's rushing line is set low at 37.5 yards, reflecting his slow start, but he could find more success against a Giants run defense that has been gashed this season.
Picks & Prediction
This NFL matchup boils down to which struggling unit can find its footing first. While both teams are 0-2, their paths to this point have been different. The Chiefs' issues stem from uncharacteristic offensive inefficiency, while the Giants have been plagued by a defense that can't get off the field.
The Chiefs' historical dominance following a loss is a powerful trend to consider; they are 14-2 straight up in their last 16 games after a defeat. Mahomes simply does not stay down for long, and this feels like a prime get-right spot against a defense allowing over 450 total yards per game.
Conversely, the Giants have been abysmal recently, with a 1-13 record in their last 14 games and a staggering 1-12 mark as an underdog in their last 13 contests. Their offensive line will be under siege from the Chiefs' league-leading blitz rate, which should disrupt Wilson's rhythm and limit opportunities for rookie standout Nabers.
While the Chiefs have their own ATS struggles (1-5 in their last six), the Giants are even worse (3-11 in their last 14). The Chiefs have also won their last six games against opponents with a losing record. Despite the Chiefs' bizarre 0-7 all-time road record against the Giants, talent and situational urgency trump historical anomaly here. I expect the Chiefs' offense to finally click and win comfortably.
Picks:
- Against the Spread: Kansas City Chiefs -6.5 (-110)
- Over/Under: Over 45.0 (-110)
- Player Prop: Malik Nabers Over 78.5 Receiving Yards (-118)
Public Betting Splits
Public betting data is not yet widely available for this matchup. However, based on the line movement, it is clear that early sharp money has favored the Chiefs, pushing the spread from -5.5 to -6.5.
As the week progresses, it is likely the public will also back the Chiefs, given the popularity of Mahomes and the expectation of a bounce-back performance against a struggling Giants team. Check back closer to kickoff for more detailed splits on betting percentages for the spread, moneyline, and total.