Week 2 of the new NFL season wraps up this evening with an exciting Monday Night Football double-header. Before the games kick off, fans can find all the best Chargers vs. Raiders ATS picks and best bets for the second game of the evening.
- Justin Herbert and the Los Angeles Chargers look to build on a big Week 1 win as they visit their AFC West rivals under the Monday night lights.
- The Las Vegas Raiders aim to defend their home turf and start 2-0, but face a team they've struggled against recently.
- This betting preview breaks down the odds, key matchups, and player props to provide the best picks for this divisional showdown.
An early-season battle for AFC West positioning takes center stage on Monday Night Football as Justin Herbert and the Los Angeles Chargers invade Allegiant Stadium to take on the Las Vegas Raiders. Both squads are coming off impressive Week 1 victories and are looking to make a statement in a division that is suddenly wide open.
Herbert was surgical in the Chargers' 27-21 Week 1 road win over the Chiefs, completing 73.5% of his passes for 304 yards and three touchdowns, posting a stellar 131.7 passer rating with zero turnovers. His command of the offense was impressive, and he'll look to exploit a Raiders secondary that showed some vulnerabilities despite a win.
For the Raiders, Geno Smith was sharp in his debut, throwing for 333 yards and a score on 70.6% passing in a 20-13 victory over the Patriots last time out. While he did toss one interception, his ability to push the ball downfield kept the offense moving.
This matchup features a classic clash of styles and strengths. The Chargers' high-powered air raid will test the Raiders' bend-but-don't-break defense, while the Raiders' collection of offensive weapons will challenge a Chargers secondary that can be susceptible to big plays. We'll dive into the odds, analyze critical player props, and deliver our top betting predictions for this primetime AFC West clash.
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The Chargers (1-0) and Raiders (1-0) will square off in a pivotal Week 2 matchup at Allegiant Stadium in Las Vegas, NV. Kickoff is scheduled for 10:00 pm ET and will be broadcast nationally on ESPN. As the game is being played inside a dome, weather will not be a factor.
Chargers vs Raiders Betting Odds
| Bet Type | Los Angeles Chargers | Las Vegas Raiders |
|---|---|---|
| Spread | -3.5 (-105) | +3.5 (-115) |
| Moneyline | -192 | +160 |
| Total Points | Over 46.5 (-112) | Under 46.5 (-108) |
Odds from DraftKings.
Moneyline (vig-free): Los Angeles Chargers \~63.1%, Las Vegas Raiders \~36.9%
The odds reflect the Chargers' status as solid road favorites, with their implied win probability sitting just over 63%. The spread of (-3.5) is significant, as it crosses the key number of three, requiring the Chargers to win by at least four points to cover.
The total is set at a healthy 46.5 points, suggesting oddsmakers anticipate a competitive, high-scoring affair. The Chargers have been a covering machine when favored, posting an 8-2 ATS record in their last 10 games in that role.
Odds Movement & Analysis
This NFL betting line has seen significant movement in favor of the visitors. The Chargers opened as 3-point favorites, and the line has since shifted to (-3.5). Similarly, their moneyline odds have steamed from an opener of (-155) to the current (-192). The total has also seen a substantial jump, climbing two full points from its opening number of 44.5 to 46.5.
This movement indicates that early and consistent money has backed the Chargers and the over. The shift across the key number of three on the spread suggests strong confidence from the market in Herbert's ability to win by more than a field goal.
The rise in the total points to a high-scoring 46.5 reflects expectations that both potent passing attacks will find success against vulnerable secondaries. While public money appears to be heavily on the Chargers, some sharp action has reportedly come in on the Raiders (+3.5) and the under, creating a classic public vs. sharp divide.
Chargers vs Raiders – Key Matchups to Watch
Herbert vs Raiders Pass Defense
Herbert was nearly flawless in Week 1, carving up the Chiefs defense with a 131.7 passer rating. He now faces a Raiders pass defense that ranked 27th in yards allowed last season and gave up 276 yards through the air in their opener. While the Raiders' defense is opportunistic and strong in the red zone, their secondary is the unit's biggest question mark. If Herbert gets time in the pocket, he has the weapons to exploit matchups all over the field.
Raiders Running Game vs Chargers Run Defense
The Raiders' ground attack was non-existent in Week 1, managing just 56 yards on 24 carries for a paltry 2.3 yards per attempt. They'll find it tough sledding against a Chargers front that held a potent Chiefs rushing attack to under 100 yards. If the Raiders can't establish any semblance of a run game, their offense will become one-dimensional, allowing the Chargers' pass rushers to pin their ears back.
Raiders Pass Catchers vs Chargers Secondary
This is where the Raiders can find an edge. Smith connected with his receivers for 333 yards in Week 1, and he has a deep group of targets including Jakobi Meyers and rookie phenom Brock Bowers. The Chargers' pass defense ranked 24th in DVOA last season and remains their biggest weakness. With injuries thinning their secondary and linebacker corps, the Raiders' pass-catchers could find plenty of open space.
Maxx Crosby vs Chargers Offensive Line
Maxx Crosby is a game-wrecker who can single-handedly disrupt an opponent's offensive game plan. The Chargers' offensive line is solid but will have its hands full. How they handle Crosby—whether through double teams, chip help from running backs, or quick passes—will be a critical factor. If Crosby consistently generates pressure, it could be the great equalizer against Herbert's high-powered offense.
Chargers vs Raiders Player Props: Passing
| Player | Passing Yards | Passing TDs | Completions | INTs |
|---|---|---|---|---|
| Justin Herbert (LAC) | 253.5 (O -111 | U -113) | 1.5 (O -125 | U -102) | 22.5 (O -110 | U -116) | 0.5 (O +118 | U -151) |
| Geno Smith (LV) | 241.5 (O -111 | U -113) | 1.5 (O +101 | U -128) | 22.5 (O -127 | U -101) | 0.5 (O -116 | U -110) |
Herbert's passing yards prop of 253.5 seems very attainable after he torched the Chiefs for 304 yards. He faces a less formidable Raiders secondary this week, making the over an attractive play.
Smith's line is set at 241.5, a number he easily surpassed with 333 yards in Week 1. However, he faces a Chargers defense that can generate more pressure than the Patriots did.
Rushing & Receiving Props
| Player | Rushing Yards | Receiving Yards | Receptions | Anytime TD |
|---|---|---|---|---|
| Omarion Hampton (LAC) | 56.5 (O -110 | U -114) | 12.5 (O -112 | U -112) | 1.5 (O -172 | U +134) | Yes -125 | No N/A |
| Ladd McConkey (LAC) | N/A | 73.5 (O -111 | U -113) | 5.5 (O -133 | U +104) | Yes +155 | No N/A |
| Ashton Jeanty (LV) | 68.5 (O -115 | U -109) | 15.5 (O -114 | U -110) | 2.5 (O +107 | U -137) | Yes -110 | No N/A |
| Jakobi Meyers (LV) | N/A | 60.5 (O -110 | U -114) | 5.5 (O -107 | U -119) | Yes +160 | No N/A |
| Brock Bowers (LV) | N/A | 61.5 (O -111 | U -113) | 6.5 (O +113 | U -144) | Yes +170 | No N/A |
NFL player props as of September 15, 2025 from DraftKings.
Ladd McConkey's receiving line is set high at 73.5 yards, indicating he's expected to be Herbert's primary target. For the Raiders, both Meyers (60.5) and Bowers (61.5) have robust receiving props, suggesting the market expects a pass-heavy game plan from Las Vegas to attack the Chargers' defensive weakness.
Chargers vs Raiders Picks & Prediction
This AFC West showdown boils down to a classic strength-on-strength and strength-on-weakness matchup. The most significant mismatch on the field is Herbert and the Chargers' passing game against the Raiders' secondary.
Herbert demonstrated elite precision and decision-making in Week 1, and he now gets a defense that is far more generous through the air than the one he just faced. While the Raiders' defense plays a tough, bend-don't-break style, they are simply not equipped to handle the Chargers' diverse array of receiving threats for four quarters.
The Raiders' inability to establish a run game in their opener is a major red flag. If they can't force the Chargers to respect the run, it will make them predictable and allow the Chargers' pass rush to attack Smith. While Smith and his receivers should find success against a banged-up Chargers defense, it's unlikely they can keep pace with Herbert's offensive machine.
The Chargers have been dominant as favorites, covering the spread in eight of their last ten opportunities. Furthermore, they are an impressive 4-1 ATS in their last five games as a road favorite. Despite the Raiders' home-field advantage, the Chargers have the superior quarterback and the more balanced team.
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Picks:
- Against the Spread: Los Angeles Chargers -3.5 (-105)
- Over/Under: Over 46.5 (-112)
- Player Prop: Justin Herbert Over 253.5 Passing Yards (-111)
Public Betting Splits
Public betting data indicates a clear divide between casual bettors and professional money. The majority of public tickets are on the Chargers to cover the spread.
However, reports suggest that sharp money has been backing the Raiders (+3.5) and the Under 46.5, which explains why the line hasn't moved past the key half-point to (-4) despite the public volume on the Chargers.