West Virginia vs BYU Odds, Picks & Player Props for Week 6

The college football season rolls along today with a high profile Big 12 matchup for fans to enjoy. Before the action kicks off, check out these West Virginia vs BYU odds, picks & player props for Week 6.

• The undefeated and #23 ranked BYU Cougars host a struggling West Virginia Mountaineers squad in a lopsided Big 12 matchup.
• BYU boasts a dominant defense, allowing just 9.3 points per game, and a punishing ground attack, creating significant mismatches against the Mountaineers.
• A colossal turnover differential (+6 for BYU, -2 for West Virginia) and a plunging game total point to a game script that heavily favors the home team covering a large spread.

A Friday night showdown in Provo features two Big 12 teams heading in opposite directions as the undefeated (#23) BYU Cougars look to continue their dominant start against the reeling West Virginia Mountaineers. The Cougars have steamrolled their early competition with a suffocating defense and a powerful rushing attack, establishing themselves as a legitimate conference contender. Quarterback Bear Bachmeier has been a model of efficiency, completing 67.8% of his passes for 697 yards and a pristine 6-0 TD-INT ratio, expertly managing a ground-and-pound offense.

Conversely, West Virginia limps into LaVell Edwards Stadium after a humbling 48-14 blowout loss to Utah. The Mountaineers have been plagued by offensive inconsistency and critical turnovers, undermining a rushing game that has shown flashes of potential. The challenge ahead is monumental: facing one of the nation's stingiest defenses in a hostile environment known for its significant home-field advantage.

This article will break down the betting odds, analyze key matchups, and provide our top picks and player props for this conference clash.

Use the BetMGM bonus code TSN150 to win $150 in bonus bets or unlock a $1,500 first bet for BYU vs. WVU.

West Virginia vs. BYU Betting Preview

West Virginia will travel to face (#23) BYU in a Week 6 conference battle at LaVell Edwards Stadium in Provo, Utah. Kickoff is scheduled for 10:30 pm ET (8:30 PM local time and the game will be broadcast nationally on ESPN. The forecast for Provo calls for clear and cool conditions, with the high elevation of 4,500 feet potentially playing a factor for the visiting Mountaineers.

West Virginia vs BYU Odds

Odds as of October 3, 2025 from BetMGM.

The odds paint a clear picture of a mismatch, with BYU installed as massive home favorites. The moneyline implies a lopsided affair, while the spread sits just shy of three touchdowns.

Moneyline (vig-free): BYU Cougars \~89.2%, West Virginia Mountaineers \~10.8%

The low total of 47.5 is particularly noteworthy, reflecting the market's high confidence in BYU's defensive prowess and West Virginia's offensive struggles. Given BYU's 3-1 ATS record this season, they have consistently met or exceeded market expectations, while West Virginia sits at 2-3 ATS.

Odds Movement & Analysis

The college football betting market has moved decisively in BYU's favor while anticipating a low-scoring game. The spread opened at BYU (-18.5) and has been bet up a full point to (-19.5), signaling that early money is backing the Cougars to win by a significant margin.

The most dramatic shift has been on the total, which opened at a healthy 51.5 and has plummeted four full points to 47.5. This substantial movement is a classic indicator of sharp money hammering the under. The reasons are clear: BYU's defense ranks 4th in the nation in points allowed (9.3 PPG), while West Virginia's offense is 92nd in scoring (22 PPG). Bettors are forecasting a game where the Cougars' defense completely smothers the Mountaineers' attack. The value on the under has likely diminished after such a large drop, but the market's direction provides a strong signal about the expected game flow.

West Virginia vs BYU – Key Matchups to Watch

Quarterback vs Pass Defense

BYU quarterback Bachmeier has been the epitome of a game manager, posting a 154.8 passer rating with zero interceptions. His job is to avoid mistakes and let the run game and defense do the heavy lifting. He faces a West Virginia pass defense that has been torched for 10 touchdowns and allows a 136.5 opponent QB rating. More importantly, BYU's offensive line has allowed only four sacks all season, giving Bachmeier a clean pocket to operate from.

Running Game vs Run Defense

This is the central mismatch of the game. The BYU Cougars feature the 9th-ranked rushing attack in the nation, bulldozing opponents for 251.3 yards per game at an explosive 6.3 yards per carry. They will square off against a West Virginia run defense that is surrendering 153 yards per game. Led by LJ Martin, BYU's offensive line should be able to create massive running lanes and control the line of scrimmage from start to finish.

Pass Catchers vs Secondary

While BYU is a run-first team, wide receiver Chase Roberts is a reliable target who can move the chains. The Mountaineers' secondary has struggled to contain primary receivers and has shown vulnerability to big plays. If West Virginia sells out to stop the run, Roberts could find himself in favorable one-on-one matchups downfield.

Offensive Line vs Pass Rush

West Virginia has managed to generate 13 sacks this season, one of the few bright spots on their defense. However, they are running into a brick wall in BYU's offensive line, which has protected its quarterback exceptionally well. If the Mountaineers can't generate pressure, BYU's offense will be able to execute its game plan without disruption, leading to long, clock-chewing drives.

West Virginia vs BYU Rushing & Receiving Props

Martin's rushing prop is the standout bet on the board. He is the lead back for a top-10 rushing offense facing a porous run defense. Given the expected game script of BYU controlling the clock with a lead, Martin should see a heavy workload and has a great chance to eclipse 100 yards.

The Over 94.5 rushing yards is one of the strongest prop bets in this game. Roberts' line of 64.5 receiving yards is also appealing, as he is the clear top target and should see opportunities via play-action.

West Virginia vs BYU Picks & Prediction

Every statistical and situational factor points toward a dominant performance from the BYU Cougars. The chasm between these two teams is immense, starting with the line of scrimmage. BYU's ground-and-pound offense, which averages over 251 rushing yards per game, is poised to physically overwhelm a West Virginia defense that has been soft against the run. This will allow the Cougars to control the clock, dictate the pace, and wear down the Mountaineers' defense.

Defensively, BYU presents a nightmare matchup for a West Virginia offense that ranks 92nd in scoring and has been a turnover machine, committing nine giveaways in five games. The Cougars' defense is not only elite at preventing points (9.3 PPG allowed) but also excels at taking the ball away, boasting a +6 turnover margin. Playing at home, at elevation, under the Friday night lights at Edwards Stadium only amplifies BYU's advantages. The sharp money has already spoken by driving the total down four points, anticipating a game where West Virginia struggles to move the ball at all.

While a 19.5-point spread is substantial, the overwhelming mismatches in the trenches, on defense, and in the turnover battle justify it. Expect BYU to establish its run game early, build a comfortable lead, and cruise to a victory that easily covers the spread. The game script strongly supports a slow-paced, run-heavy second half, making the under a solid play despite the significant line movement.

Claim the DraftKings promo code to score an offer to win $200 in bonus bets with just a $5 wager.

Picks:

• BYU -19.5 (-109)
• Under 47.5 (-112)
• Player Prop: LJ Martin Over 94.5 Rushing Yards (-115)