Ole Miss vs. Kentucky Betting Preview: Odds, Picks, and Predictions for Saturday SEC Matchup

Alex Payton

Ole Miss vs. Kentucky Betting Preview: Odds, Picks, and Predictions for Saturday SEC Matchup image

This afternoon will see a massive SEC showdown, and college football fans can get an Ole Miss vs. Kentucky Betting Preview here with all the latest odds, picks, and predictions. Each of these teams carries a (1-0) record into this afternoon's showdown as they look to score an early-season conference victory.

  • Ole Miss seeks revenge for last year's playoff-derailing upset, bringing a high-powered offense to Lexington.
  • Kentucky aims to control the clock and dictate the game's pace with a consistent ground game and stout run defense.
  • A massive quarterback disparity favors the Rebels, but the Wildcats have a strong history of covering as home underdogs in SEC play.
 

An early-season SEC clash with significant implications is set for Lexington as the Ole Miss Rebels travel to face the Kentucky Wildcats. This matchup is dripping with narrative, headlined by the Rebels' quest for revenge after a stunning 20-17 home loss to the Wildcats last season that torpedoed their playoff aspirations. Ole Miss enters with an explosive air-raid attack, while Kentucky plans to grind out a victory with a physical defense and a clock-chewing ground game.

The quarterback battle pits two players on opposite ends of the performance spectrum. Ole Miss's Austin Simmons was electric in Week 1, completing 64.9% of his passes for 400 yards and 4 touchdowns, orchestrating an offense that looked nearly unstoppable. On the flip side, Kentucky's Zach Calzada struggled mightily in his season opener, connecting on just 43.5% of his attempts for a meager 85 yards with no touchdowns and one interception. For Kentucky to pull off another upset, they'll need to control the line of scrimmage and keep Simmons and his playmakers on the sideline.

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Ole Miss vs. Kentucky Betting Preview

This preview will break down the odds, analyze key matchups, and provide our top betting picks and player props for this compelling SEC showdown.

The Ole Miss Rebels (1-0) and Kentucky Wildcats (1-0) will square off in a pivotal conference game at Kroger Field in Lexington, KY. Kickoff is scheduled for 3:30 PM ET with a broadcast on ABC.

Odds on BetMGM Sportsbook

Bet TypeOle Miss RebelsKentucky Wildcats
Spread-10 (-110)+10 (-110)
Moneyline-376+293
Total PointsOver 50.5 (-110)Under 50.5 (-110)

The odds show Ole Miss as a significant 10-point road favorite, reflecting their explosive offensive output in Week 1 and the likely quarterback advantage. The moneyline implies the Rebels have a greater than 75% chance of winning outright.

The Wildcats have historically been a tough out at home, covering the spread in 62% of their games as a home underdog in SEC play over the last five seasons, making the double-digit spread an intriguing proposition for bettors backing the Wildcats.

Ole Miss Rebels vs Kentucky Wildcats Odds Movement & Analysis

The most significant line movement in this matchup has been on the total, which opened at 54.5 and has been bet down a full four points to 50.5. This sharp drop indicates that while the public may be enamored with the Ole Miss offense, professional bettors respect Kentucky's ability to control the game's tempo with its run-heavy approach and physical defense. The Wildcats' defense excels at stopping the run, which could force longer drives and chew up the clock, favoring an under.

 

 

The point spread opened with Ole Miss as a 9.5-point favorite and has ticked up slightly to -10, suggesting steady money on the road team. However, the falling over-under total suggests the college football betting public doesn't expect a blowout. This sets up for a classic clash of betting philosophies: do you back the explosive offense to cover a big number, or trust the home underdog's proven ability to slow the game down and keep it close?

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Ole Miss Rebels vs Kentucky Wildcats – Key Matchups to Watch

Quarterback vs Pass Defense

This is the game's biggest mismatch on paper. Simmons and the Ole Miss air attack posted 400 yards in their opener, showcasing a vertical passing game that can score from anywhere. They face a Kentucky pass defense that was respectable but allowed 270 yards in Week 1.

For the Wildcats to have a chance, their pass rush, which generated three sacks last week, must consistently disrupt Simmons's timing. On the other side, Calzada's 85-yard, one-interception performance inspires little confidence. He faces an Ole Miss secondary that allowed just 69 passing yards, albeit against lesser competition.

Running Game vs Run Defense

Here is where the game will be won or lost. Ole Miss rumbled for 295 yards at a blistering 6.7 yards per carry in their first game. However, they now face the teeth of the Kentucky defense. The Wildcats were utterly dominant against the run in their opener, surrendering just 59 yards on the ground and a paltry 2.0 yards per attempt.

If Kentucky can neutralize the Rebels' ground game and make them one-dimensional, it dramatically increases their chances. Conversely, Kentucky's offense is built on its ground-and-pound attack, which churned out 220 rushing yards. They have a significant advantage against an Ole Miss run defense that was gashed for 191 yards and 5.5 yards per carry.

Pass Catchers vs Secondary

Ole Miss receiver Harrison Wallace III is a premier vertical threat who will test the Kentucky secondary all afternoon. The Rebels will try to scheme mismatches against a Kentucky secondary that's vulnerable to explosive plays.

Kentucky receivers Tayvion Robinson and Barion Brown excel at contested catches and will need to win their one-on-one battles to give Calzada viable targets against an aggressive Ole Miss secondary.

Offensive Line vs Pass Rush

Kentucky's offensive line did not allow a sack in Week 1 and is the engine of the Wildcat rushing attack. Their ability to generate a push against the Ole Miss front seven will be everything. The Rebels' pass rush, led by Zxavian Harris, will look to exploit any weakness to create pressure on Calzada, who has struggled when moved off his spot. The Ole Miss offensive line allowed only one sack, but it will face a much tougher test against a Kentucky front that can generate pressure without blitzing.

Ole Miss-Kentucky Player Props

Simmons' passing yards prop is set at 275.5, well below his 400-yard Week 1 performance. This line reflects the step up in competition and Kentucky's defensive prowess. However, if the Wildcats successfully stifle the Rebels' run game, Ole Miss will be forced to lean on Simmons' arm, making the over an attractive play.

Calzada's line is set at a very low 158.5 yards, a direct reflection of his struggles and Kentucky's offensive game plan. The heavy juice on his over 0.5 passing TDs (-250) suggests oddsmakers expect at least one score through the air, but his yardage total remains a major question mark.

Rushing & Receiving Props

PLayerRushing YardsReceiving YardsReceptionsAnytime TD
Kewan Lacy (MISS)65.5 (O -114 | U -120)N/AN/AYes -156 | No +120
Seth McGowan (UK)61.5 (O -118 | U -118)N/AN/AYes +133 | No -175
Harrison Wallace (MISS)N/A56.5 (O -120 | U -114)N/AYes +120 | No -150
De'Zhaun Stribling (MISS)N/A44.5 (O -114 | U -114)N/AYes +186 | No -250
Jay Maclin (UK)N/A24.5 (O -114 | U -114)N/AYes +259 | No -360

Lacy's rushing prop of 65.5 yards seems high given the matchup against Kentucky's elite run defense that allowed only 59 total rushing yards in Week 1. This looks like a strong spot to play the under.

For Kentucky, McGowan's line of 61.5 rushing yards is achievable, as the Wildcats will likely lean on him heavily to control the clock against a porous Ole Miss run defense. Wallace's receiving prop of 56.5 yards is tempting for an over, as he is the clear top target for Simmons and a big-play threat.

Ole Miss vs. Kentucky Final Prediction

This game hinges on one central theme: can Kentucky's physicality and home-field advantage overcome a massive deficit at the quarterback position? The Ole Miss offense is a juggernaut, capable of scoring in bunches through the air and on the ground.

However, their path to victory runs directly into Kentucky's greatest strength: a suffocating run defense that ranked among the nation's best in Week 1. If the Wildcats can force Simmons and the Rebels into obvious passing situations, their pass rush has a chance to make an impact and keep the game close.

Kentucky's offensive formula is clear: establish the run, control the clock, and limit possessions. They have a decisive advantage on the ground against an Ole Miss defense that was soft up the middle last week. The environment at Kroger Field is a legitimate factor, and the Wildcats have consistently played above their heads in these spots.

The situational trend is undeniable: Kentucky is 6-4 ATS in their last 10 games and has covered in 62% of their contests as a home underdog in the SEC over the past five seasons. While an outright upset is a tall order given Calzada's limitations, keeping this game within double digits is well within reach. The massive line movement on the total, dropping from 54.5 to 50.5, is a clear signal from the market that this game will be played on Kentucky's terms.

Picks:

  • Kentucky +10 (-110)
  • Under 50.5 (-110)
  • Kewan Lacy Under 65.5 Rushing Yards (-120)

Public Betting Splits

The public betting money is heavily favoring the Ole Miss Rebels to cover the spread, drawn in by their explosive Week 1 performance and the revenge narrative. Reports indicate that sharp, professional money is more divided, with some respected bettors taking Kentucky and the points, believing the spread is inflated and respecting the Wildcats' ability to control the game at home.

Recent History: Rebels vs. Wildcats

These two NCAAF teams met last season in Oxford, with Kentucky pulling off a shocking 20-17 upset as a significant underdog. That loss was a critical blow to the Rebels' College Football Playoff hopes and serves as the primary motivation for Ole Miss heading into this rematch.

The last four meetings between these schools have been decided by a single score, highlighting a competitive series despite differing team trajectories.

Alex Payton

Alex Payton is a betting content producer for The Sporting News. A resident of Kentucky, Alex graduated from the University of Louisville in 2017 and is a devoted Cardinals fan. He has several years of experience creating dedicated content for various publications in the online sports betting industry.