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Indiana vs. Oregon Picks: Our Best Bets for Top 10 Showdown

Alex Payton

Indiana vs. Oregon Picks: Our Best Bets for Top 10 Showdown image

© Ben Lonergan/The Register-Guard / USA TODAY NETWORK via Imagn Images

Week 7 college football action heads to Eugene this afternoon for a massive top ten showdown, and fans can get the best Indiana vs. Oregon betting pick to take their best shot at wagering on the high-stakes matchup.

 
  • Two undefeated Big Ten powerhouses clash in a game with significant College Football Playoff implications.
  • The Oregon Ducks' elite offensive line, which has allowed only one sack all season, faces a ferocious Indiana Hoosiers pass rush that has racked up 16 sacks.
  • With two of the nation's top defenses on display, the game total of 55.5 points presents a compelling betting angle for the under.

A potential preview of the Big Ten Championship game is on tap for Week 7 as the undefeated Indiana Hoosiers travel to Eugene to take on the undefeated Oregon Ducks. This heavyweight bout features two of the most statistically dominant teams in the nation, each boasting a high-powered offense and a shutdown defense, setting the stage for a classic gridiron chess match with playoff hopes hanging in the balance.

The quarterback duel will be front and center. Oregon's Dante Moore has been a model of efficiency, completing 74.6% of his passes for 1,210 yards with a stellar 14-to-1 touchdown-to-interception ratio. Across the field, Indiana's Fernando Mendoza has been even more prolific, connecting on 73% of his attempts for 1,208 yards and an eye-popping 16 touchdowns against just one interception. With both signal-callers protecting the football and leading explosive attacks, the game will likely hinge on which defense can disrupt rhythm and create negative plays.

This article will break down the betting odds, analyze critical matchups, and provide our top picks and player props for this colossal conference showdown. We'll explore where the value lies in the spread, total, and player prop markets to help you make your most informed wagers.

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Indiana vs. Oregon Betting Picks

Indiana, holding an unblemished record, will march into the hostile environment of Autzen Stadium in Eugene, OR, to face the equally perfect Oregon Ducks. This pivotal conference game is scheduled for 3:30 pm ET, and fans can catch the national broadcast on CBS. As this is an outdoor venue, weather could be a factor, with the forecast worth monitoring closer to game day.

Indiana vs Oregon Betting Odds

Bet TypeIndiana HoosiersOregon Ducks
Spread+7.5 (-115)-7.5 (-105)
Moneyline+240-300
Total PointsOver 55.5 (-105)Under 55.5 (-115)

The odds establish the Ducks as more than a touchdown favorite at home, a testament to the significant home-field advantage at Autzen Stadium. The (-300) moneyline on Oregon suggests a high probability of victory, while the (+240) on Indiana offers a substantial payout for an upset.

After removing the vig, the moneyline implies a 71.8% chance for an Oregon win and a 28.2% chance for Indiana. Both teams enter the contest with identical 3-2 against-the-spread (ATS) records, indicating that while dominant, they haven't consistently covered larger spreads.

Indiana vs Oregon Odds Movement & Analysis

The college football betting lines for this contest have seen some subtle but telling movement. The spread has held firm at Oregon (-7.5), but the juice has shifted from (-112) on the Ducks to (-105), suggesting some respected money has come in on the Indiana Hoosiers to keep the game within the number. The moneyline has also tightened slightly, moving from an open of Oregon (-311) down to (-300).

The most significant shift has occurred on the total, which opened at 54.5 and has been bet up a full point to 55.5. Early money likely favored the over, given the explosive nature of both offenses. However, with the juice now shaded to the under at (-115), it signals that the new, higher number is attracting sharp action on a defensive battle. This presents a classic sharp vs. public disagreement, creating potential value for bettors who believe these elite defenses will control the game.

Indiana vs Oregon – Key Matchups to Watch

Quarterback vs Pass Defense

This is the premier matchup of the game. Moore (242 YPG, 14 TD, 1 INT) pilots the efficient Oregon air attack against an Indiana secondary that has been a black hole for opposing quarterbacks. The Hoosiers' defense allows a meager 157.3 passing yards per game, has surrendered only one passing touchdown all season, and has collected seven interceptions.

Conversely, Mendoza (241.6 YPG, 16 TD, 1 INT) faces a similarly daunting Oregon pass defense that gives up just 104.8 yards per game and has five interceptions of its own. The quarterback who can better navigate the storm will give his team a massive edge.

Running Game vs Run Defense

Both teams feature a punishing ground-and-pound attack to complement their passing games. The Oregon Ducks average an impressive 236 rushing yards per game at 6.2 yards per carry. They'll be running into a brick wall in the Indiana Hoosiers' front seven, which yields only 100.3 rushing yards per game and 3.8 yards per carry.

Indiana's own rushing attack is even more potent, churning out 260.3 yards per game, but will face a stout Oregon run defense that allows just 132 yards on the ground. The battle in the trenches will be violent and decisive.

Pass Catchers vs Secondary

Indiana's top target, Elijah Sarratt, will be tested by Oregon's lockdown corners. Sarratt's receiving yards prop is set at 75.5, a number he may struggle to reach against a defense that suffocates passing lanes.

For the Oregon Ducks, Dakorien Moore (54.5 receiving yards prop) and Kenyon Sadiq (52.5) lead a balanced receiving corps. They face an Indiana secondary that excels at preventing explosive plays, making every downfield shot a high-risk, high-reward proposition.

Offensive Line vs Pass Rush

Perhaps the most critical mismatch lies here. The Ducks' offensive line has been an impenetrable fortress, allowing just a single sack through five games. This unit will face its toughest test against an Indiana defensive line that has generated 16 sacks.

If Oregon's front five can neutralize the Hoosiers' pass rush and keep Moore upright, their offense should find its rhythm. If Indiana can generate pressure, it could completely disrupt Oregon's offensive game plan.

Indiana vs Oregon Player Props: Passing

Both quarterbacks face passing yardage props well below their season averages, a direct reflection of the elite defenses they are up against. Mendoza's line of 227.5 yards is more than 10 yards below his average, while Moore's 252.5 is about 10 yards north of his typical output.

The most telling line is Moore's passing touchdowns at 2.5, with heavy juice on the under (-191). Oddsmakers clearly respect an Indiana defense that has allowed only one passing score all year.

Rushing & Receiving Props

PlayerRushing YardsReceiving YardsReceptionsAnytime TD
Roman Hemby (IND)63.5 (O -116 | U -114)N/AN/AYes +146 | No N/A
Elijah Sarratt (IND)N/A75.5 (O -115 | U -115)5.5 (O -114 | U -114)Yes -121 | No N/A
Dierre Hill (ORE)45.5 (O -115 | U -115)N/AN/AYes +113 | No N/A
Dakorien Moore (ORE)N/A54.5 (O -115 | U -115)3.5 (O -114 | U -114)Yes +154 | No N/A

Roman Hemby faces a tough Oregon run defense, but his rushing prop of 63.5 yards seems attainable for the Hoosiers' lead back. Sarratt's props are ambitious against a secondary that has shut down top receivers all season. For the Ducks, the backfield workload appears split, making Dierre Hill's prop of 45.5 yards a reflection of a committee approach. The modest receiving props for Oregon's pass-catchers further underscore the expectation of a tough, defensive-minded game.

Indiana vs Oregon Betting Picks & Prediction

 

In a matchup of two statistically similar juggernauts, the betting edge is often found in the margins, and for this game, those margins point toward the home team and a lower-scoring affair. Both the Hoosiers and Ducks boast top-tier units on both sides of the ball, but Oregon's advantages at home and along the offensive line are too significant to ignore. Autzen Stadium is one of the most difficult places to play in college football, and that crowd noise will be a major factor against an Indiana offense that needs to communicate effectively.

The single most important factor in this game will be the Oregon offensive line's ability to protect Dante Moore. Having allowed only one sack all season, they have the talent and cohesion to neutralize Indiana’s aggressive pass rush. If Moore has time in the pocket, he will find holes in the Hoosiers' secondary, even against tight coverage. While both defenses are elite, Oregon's ability to sustain drives by protecting their quarterback gives them a higher floor.

The line of 7.5 points is key, but at home, the Ducks have the firepower to win by more than a touchdown. The under also holds significant value. The market has pushed the total up to 55.5, creating a prime opportunity to bet against a public expectation of a shootout. These are two of the best defenses in the country, allowing a combined 21.4 points per game. Expect a physical, hard-fought game where points are at a premium.

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Picks:

  • Oregon -7.5 (-105)
  • Under 55.5 (-115)
  • Player Prop: Dante Moore Under 2.5 Passing TDs (-191)

Alex Payton

Alex Payton is a betting content producer for The Sporting News. A resident of Kentucky, Alex graduated from the University of Louisville in 2017 and is a devoted Cardinals fan. He has several years of experience creating dedicated content for various publications in the online sports betting industry.