There are 15 NFL games remaining in Week 4. Below, we explain our favorite NFL picks against the spread for each matchup. Take advantage of several sportsbook bonuses to make these wagers.
Best NFL ATS Picks & Sportsbook Odds
After several weeks of action, we have a better idea on rookies, new coaches and impacts of trades. Make these NFL picks against the spread using several NFL betting offers, such as a $200 instant bonus on DraftKings Sportsbook.
Vikings vs. Steelers
This game is being played in Dublin, Ireland at Croke Park, with the Vikings as slight favorites. While it's hard to put money on Aaron Rodgers in the year 2025, the reality is Carson Wentz is even worse. One blowout win against the Bengals where the Vikings defense had two touchdown themselves is not enough to take us off the fade Wentz scene.
Pick: Steelers +2.5 (-110) BetMGM
Commanders vs. Falcons
There is a wild range of spreads on this one, with majority of books having the Commanders as one-point favorites. That said, some books have the Commanders -1.5, while other books have them +1.5. This is admittedly a tough game to predict without knowing for sure who is playing football for the Commanders, but it looks as though, at least as of the time of this writing, that QB Jayden Daniels will be starting and WR Terry McLaurin is out. Daniels is good enough for the Commanders to take this one.
Pick: Commanders -0.5 (-110) Fanatics Sportsbook
Saints vs. Bills
This is a huge spread, but the Bills are not shy to blow teams out and the Saints just lost by 31 to the Seahawks.
Pick: Bills -15.5 (-110) FanDuel
Browns vs. Lions
This is an almost even split between books that have this as Lions either -9.5 or -10. It makes sense, but this Browns defense is legit, and it would not be a total shock to see the Lions have a mini let-down game after taking it to the Ravens on MNF. Lions win, but the Browns cover.
Pick: Browns +10 (-112) Caesars Sportsbook
Titans vs. Texans
Gross. This game features two of the worst offenses in the NFL, and two good defenses. One might prefer to watch paint dry instead of either of these offenses, but 7 points is simply too many for the 0-3 Texans who have not been able to do anything on offense.
Pick: Titans +7 (-105) DraftKings
Panthers vs. Patriots
The Panthers surprised everybody and not only beat the Falcons last week but completely shut them out 30-0. The Panthers still have a lot of issues on defense, but the Patriots are not exactly a well-oiled machine either, so we'll take the points with the road team here.
Pick: Panthers +5.5 (-110) DraftKings
Chargers vs. Giants
While there is a lot of excitement in New York, with Jaxson Dart starting for the Giants over the now-benched Russell Wilson, this is a tough test against a red-hot Chargers team. It is hard to trust Dart going up against a good defense in his first start, so trust the Chargers to stay hot here.
Pick: Chargers -6 (-110) DraftKings
Eagles vs. Buccaneers
The Eagles finally learned that they are allowed to throw the ball down the field last game, and it only took a 26-7 deficit to do so. It remains to be seen if they try that again, but Bucs head coach Todd Bowles has had the Eagles number, as Hurts is only 1-5 against the Bucs in his career. Even though they are banged up, the Buccaneers cover in 100-degree weather Sunday.
Pick: Buccaneers +3.5 (-110) BetMGM
Colts vs. Rams
This is a fun one, as the Colts, and Daniel Jones specifically, have shocked everybody to a 3-0 start and have looked legitimately good while doing so. That said, the Rams are two-blocked field goals away from being 3-0 coming off an impressive win in Philadelphia. This is a tough test going against a good Rams team, one that the Colts cannot pass.
Pick: Rams -3.5 (-105) Fanatics Sportsbook
Jaguars vs. 49ers
The 49ers keep suffering devastating injury after devastating injury, this time with DL Nick Bosa out for the year with a torn ACL. It does not feel great backing the Jaguars, but the 49ers will not always be able to squeak these games out.
Pick: Jaguars +3.5 (-115) Caesars Sportsbook
Ravens vs. Chiefs
The fun part about this one is that one of these teams is going to start 1-3. The Ravens have lost two tough games against the Bills and Lions, while the Chiefs, even in a win last week, did not exactly inspire any pride beating the lowly Giants. Ravens bounce-back
Pick: Ravens -2.5 (-115) BetMGM
Bears vs. Raiders
This is another game, like Commanders/Falcons mentioned earlier, where there is a wide range of spread. Some books have the Bears at +1.5, while others have them down at -1.5 (granted, for +100 odds.) The Bears seem to have figured some stuff out on offense under new head coach ben Johnson, while the Raiders have been lifeless for two games in a row after a Week 1 win.
Pick: Bears +0.5 (-110) Fanatics Sportsbook
Packers vs. Cowboys
An incredibly juicy SNF game this week, with a ton of storylines associated with them. It is a bummer that CeeDee Lamb went down, and that the Cowboys look like a trainwreck, as it would have been much more fun if the Cowboys were good. Packers win, Packers cover, Micah Parsons gets a sack.
Pick: Packers -6.5 (-110) ESPN BET
Jets vs. Dolphins
It is always fun to have 0-3 vs. 0-3 on Monday Night Football. The Jets almost pulled off an impressive comeback last week against the Buccaneers, while the Dolphins lost in a somewhat respectable game to the Bills. Toss up here, so might as well take the team getting a field goal.
Pick: Jets +3 (-118) DraftKings
Bengals vs. Broncos
This had the makings of a fun game that was turned upside down after the Joe Burrow toe injury in Week 2. The biggest mismatch in this game is the Bengals OL vs. the Broncos DL, and we've seen time and time again the Bengals not be able to hold up up-front and pay the price.
Pick: Broncos -7.5 (-105) FanDuel