Giants vs. Patriots Props, Picks, Best Bets for Monday Night Football

The Monday Night Football spotlight illuminates a compelling clash of offensive philosophies as the New York Giants travel to face the New England Patriots at Gillette Stadium. This primetime showdown features intriguing storylines on both sides, headlined by Patriots second-year quarterback Drake Maye, who has been a revelation with his 110.7 passer rating this season.

Giants vs Patriots Props, Picks, and Best Bets

For the Giants, quarterback Jaxson Dart returns from concussion protocol after missing two games, eager to build on the offensive explosiveness displayed in their recent 34-27 loss at Detroit. Despite the defeat, the Giants' aerial attack showed promise, with backup Jameis Winston torching the Lions for 395 passing yards. The player props market presents fascinating opportunities as these contrasting offensive identities collide on December 1, 2025, at 8:15 PM EST on ESPN.

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Giants vs Patriots Betting Odds

The betting market positions the Patriots as decisive home favorites, reflecting their superior season performance and recent momentum against a struggling Giants squad.

• Moneyline: Patriots -385 | Giants +300
• Spread: Patriots -7.5 (-102) | Giants +7.5 (-118)
• Total: Over/Under 46.5 (-110/-110)

Odds courtesy of MGM.

The Patriots' -385 moneyline implies strong market confidence in their victory probability, while the 7.5-point spread sits at a key number requiring New England to win by more than a touchdown. Notably, the total has moved down from its 48-point opening to 46.5, suggesting market expectations for either defensive dominance or weather-related scoring suppression. This line movement, combined with the Patriots' slight moneyline shortening from -417, indicates sustained confidence in New England's ability to control this Monday Night Football encounter.Typical Conditions: Not specified by available data

Top Player Props for Giants vs Patriots

The player props market reveals compelling narratives across multiple positions, with oddsmakers showing clear confidence in certain performances while offering intriguing value elsewhere.

Passing Props

The market demonstrates substantial confidence in Patriots quarterback Drake Maye, whose passing touchdowns prop sits at 1.5 with heavy juice favoring the over at -182, steaming from its -161 opening. His pass completions line has similarly tightened, with the over moving from -120 to -133, suggesting bettors anticipate a high-volume, efficient performance from the rookie signal-caller.

Conversely, Jaxson Dart's passing yards total sits 40 yards lower at 204.5, reflecting concerns about his ability to move the ball consistently against a Patriots defense that has forced 13 turnovers. However, his 1.5 passing touchdowns over at +145 presents potential value for those believing the Giants can find the end zone through the air.

Rushing & Receiving Props

Henderson's explosive recent performance has the market bullish on his prospects, with his rushing yards over at 60.5 heavily favored at -149. This confidence extends to his workload, as his rushing attempts prop (Over 14.5) carries -125 odds. For the Giants, Wan'Dale Robinson emerges as their primary receiving threat with a 59.5-yard line and 5.5 receptions, while Patriots veteran Stefon Diggs offers plus-money value at +110 for his over 4.5 receptions.

Touchdown Scorer Props

Henderson stands as the overwhelming favorite to find paydirt, with his anytime touchdown odds shortening from -110 to -116. The market's confidence in his goal-line opportunities is further evidenced by his +533 first touchdown scorer odds, the shortest among all players. For the Giants, Tyrone Tracy (+223) and Wan'Dale Robinson (+225) represent nearly identical touchdown probabilities, while both quarterbacks offer intriguing rushing touchdown value near the goal line.

Expert Player Prop Picks for Giants vs Patriots

After analyzing the statistical matchups and market trends, several player props emerge as premium betting opportunities. The Patriots' red zone efficiency and the Giants' turnover struggles create clear pathways to profitable wagers.

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Lock of the Week: TreVeyon Henderson Anytime Touchdown Scorer (-116)

Henderson has established himself as the focal point of New England's red zone offense. The market has responded accordingly, making him the only player with minus odds to score.

The Fearless Forecast Analysis:
Henderson's touchdown probability stems from multiple convergent factors. The Patriots boast a potent red zone offense, converting 54.8% of their attempts into touchdowns, with Henderson serving as the primary beneficiary inside the 20-yard line. New England's high-scoring offense averages 26.0 points per game compared to the Giants' modest 21.8 PPG, providing significantly more touchdown opportunities.

The anticipated game script strongly favors Henderson's prospects. As 7.5-point home favorites, the Patriots project to control this contest, particularly in the second half when they'll likely lean on their ground game to protect leads. The market's confidence in Henderson's workload is evident in the heavy action on his rushing yards (60.5) and attempts (14.5) props.

Pick: TreVeyon Henderson Anytime Touchdown Scorer (-116)

Premium Play: Jaxson Dart Over 0.5 Interceptions Thrown (-110)

The Giants' season-long struggles with ball security create an exploitable angle against a Patriots defense that has capitalized on opponent mistakes.

Statistical Foundation:
New York enters with a -6 turnover differential and 13 total turnovers, earning them the designation of a "turnover-prone offense." The Patriots' opportunistic defense has secured 8 interceptions, positioning them well to capitalize on Dart's potential mistakes. As 7.5-point underdogs, the Giants will likely face negative game script scenarios, forcing Dart into high-volume passing situations where pressure and desperation increase turnover probability.

Dart's return from concussion protocol adds another layer of uncertainty. Quarterbacks returning from head injuries often display initial rust or hesitation, particularly when facing pass rush pressure. The Patriots' defensive front should create enough discomfort to generate at least one costly mistake.

Pick: Jaxson Dart Over 0.5 Interceptions (-110)

Same Game Parlay Opportunity

This correlated parlay builds on the narrative of Patriots offensive efficiency combined with Giants desperation passing, creating a high-probability combination.

This three-leg parlay leverages the most probable game outcomes while maintaining correlation between successful Patriots offense and increased Giants passing volume. The combined odds offer significant payout potential while focusing on the most likely individual performances.

Giants vs Patriots Injury Report Analysis

Both teams enter Week 13 with extensive injury concerns, as 23 total players appear on the combined injury reports. However, the offensive skill position players appear largely healthy, with key contributors positioned to play significant roles.

The most significant injury concern involves Giants defensive lineman Dexter Lawrence II, whose elbow injury could dramatically impact his run-stopping effectiveness. Any reduction in Lawrence's dominance would create massive advantages for the Patriots' ground attack, making Henderson's rushing props particularly attractive.

Giants quarterback Jaxson Dart, wide receiver Wan'Dale Robinson, and receiver Darius Slayton all practiced fully despite previous injury designations, ensuring their availability for Monday night's primetime showcase.