Bills vs Patriots Betting Promos, Preview for Sunday Night Football

A pivotal Week 5 AFC East showdown is set for Sunday Night Football, as the New England Patriots travel to Highmark Stadium to take on the Buffalo Bills. As these division rivals prepare for kickoff, sports bettors have a prime opportunity to capitalize on a variety of new user welcome bonuses from the nation's leading sportsbooks.

Bills vs Patriots Betting Promos

There are up to six different new betting promotions available that can be used to wager on this matchup or any other NFL game on this week's schedule, providing multiple ways to unlock bonuses and build a bankroll for the football season.

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bet365 Bonus Code TSN365: Claim a $200 Bonus or $1K Safety Net for the NFL

One of the most flexible offers on the market comes from bet365, which gives new users the power to choose their own sign-up bonus. By using the bet365 bonus code TSN365, you can unlock one of two powerful promotions ahead of this week's NFL action.

This dual-offer structure caters to all types of bettors, from first-timers to seasoned veterans. Here's how you can choose the bonus that best fits your strategy:

Option 1: Bet $5, Win $200 in Bonus Bets (Guaranteed!)
This is an ideal choice for bettors who want to secure a victory right from the start. Simply place a qualifying wager of at least $5 on any market for an upcoming NFL game. Once your bet settles, bet365 will credit your account with $200 in bonus bets, regardless of whether your initial wager wins or loses. It's a low-risk way to build a bankroll instantly.

Option 2: $1,000 First Bet Safety Net
For those looking to make a bigger splash with their first bet, the Safety Net is the perfect option. Place your first real-money wager of up to $1,000 on any NFL game. If that bet doesn't win, bet365 will refund your entire stake in the form of bonus bets. This promotion allows you to make a confident, high-stakes play knowing you have a second chance if things don't go your way.

To claim your preferred offer, simply sign up with bonus code TSN365, make a deposit, and choose the promotion that aligns with your betting goals.

Sunday Night Football bettors can claim even more bonuses for betting on the primetime action with offers from FanDuel, DraftKings, Fanatics, and Caesars Sportsbook linked below.

• Sign-up for an account here to get the DraftKings promo code offer that allows new users to bet $5 and get $200 in bonus bets (if your bet wins)
• The linked FanDuel Sportsbook promo code here allows new users to get started fast with an offer to bet $5 and get $300 in bonus bets (if they win).
• Sign-up with the link here to claim the Caesars Sportsbook promo code TSN20X and receive a new player offer to bet $1 and get twenty (20) 100% Profit Boosts.
• Click here to claim the Fanatics Sportsbook promo code offer to bet $10 and get $100 in FanCash + up to $100 back in FanCash every football gameday.

BetMGM Bonus Code TSN1500: Claim $1,500 First Bet

"The King of Sportsbooks," BetMGM, delivers a royal welcome with two distinct sign-up bonuses tailored to your location. By using the correct bonus code, new bettors can unlock significant value for the upcoming NFL slate.

For most new players: Use bonus code TSN1500 to claim a massive $1,500 First Bet Offer. This promotion is perfect for those who want to swing for the fences on their first NFL wager. Simply sign up, make a deposit, and place your first bet of up to $1,500. If your bet doesn't hit, BetMGM will refund your stake in the form of bonus bets, giving you a valuable second chance to win big.

For players in MI, NJ, PA & WV: A different but equally compelling offer is available. New users in these states can use the bonus code TSN150 to activate a special promotion: Bet $10, Get $150 in bonuses with a win. This is a fantastic low-entry offer that can multiply your initial investment if your first $10 wager is successful, setting you up with a solid bonus bankroll for more NFL action.

Choose the code that applies to your state and get in the game with BetMGM's elite betting platform.

Patriots vs. Bills Betting Overview

This pivotal AFC East clash is the Sunday Night Football matchup for Week 5 as the New England Patriots travel to face the Buffalo Bills at Highmark Stadium in Orchard Park, NY. The matchup showcases two offenses with contrasting statistical profiles - the Bills boast a high-powered attack averaging an impressive 33.2 points and 404 total yards per game, while the Patriots offense has produced 25 points per game.

A critical factor in this outdoor contest could be ball security, where the Patriots enter with a positive turnover differential of +3, while the Bills have struggled in that department with a -3 differential. The game will be played on artificial turf, and as an outdoor venue, weather conditions could potentially impact the flow of the game.

Patriots vs. Bills Betting Odds

Consensus odds as of Oct. 3, 2025. Subject to change.

Fearless Forecast: Bills Face Patriots' ATS Magic

Narrative: The Bills enter this Week 5 matchup as heavy home favorites, with the moneyline implying a 77.6% chance for Buffalo to win compared to 22.4% for the Patriots. Buffalo's status is well-earned - they've won all three of their games as a favorite this season and have emerged victorious in their last 10 games when favored by a touchdown or more.

But here's where it gets spicy for us fearless forecasters: the Patriots have been covering machines against their division rivals, going 4-0 ATS in the last four head-to-head meetings. Buffalo, meanwhile, sits at 0-4 ATS in those same four contests. That's the kind of trend that makes seasoned bettors sit up and take notice.

The Bills' home dominance is real - they're humming at 33.2 points per game and creating an electric atmosphere at Highmark Stadium. However, desperation figures to kick in for a Patriots squad that knows how to play spoiler in big spots. With New England's +3 turnover differential compared to Buffalo's -3 mark, ball security could be the great equalizer in what should be a hostile environment.

Pick: Patriots (+8) - This rebound-minded Patriots squad will keep it close enough to cover.

Lock of the Week: Over 49.5 Points

Narrative: When we're talking about a 49.5-point total, all roads lead to the Over in this AFC East showdown. The Bills' explosive offense has been ripping through defenses, and their home games have been absolute fireworks shows - the Over has cashed in all three of Buffalo's home contests this season.

The historical trends slam the door on any Under consideration. The Over has hit in four of the last five Patriots-Bills meetings, and we're looking at nine Over results in New England's last 10 games against opponents with winning records. Both offenses figure to rev up in what could be a statement game for each squad.

Josh Allen's dual-threat capability, combined with the Patriots' desperation to keep pace in a high-scoring affair, creates the perfect storm for points. Even if one offense sputters, the pace and urgency of this division rivalry should push this total well beyond the posted number.

Pick: Over 49.5 - Lock of the Week. This one goes to the house with points to spare.

Patriots vs. Bills Anytime Touchdown Scorer Props

With a high game total suggesting a potential shootout, the anytime touchdown scorer market is buzzing with opportunities for this AFC East showdown. The Bills' explosive offense, which averages 33.2 points per game, features several players with short odds to find pay dirt. For the Patriots, a few key playmakers offer significant value if they can capitalize on their scoring chances.

As reflected in the odds, oddsmakers heavily favor Buffalo's top offensive weapons to score. Running back James Cook is the prohibitive favorite at (-221), a nod to his role as the lead back in Buffalo's high-octane attack. Not far behind is quarterback Josh Allen at (-128), whose dual-threat ability makes him a constant goal-line threat and a nightmare for opposing defenses.

For those looking for a better return on the Buffalo side, receiver Keon Coleman presents a solid option at (+175) to find the end zone. For New England, the path to pay dirt is reflected in longer, more valuable odds that could pay off handsomely. Running back Rhamondre Stevenson (+218) and tight end Hunter Henry (+232) are considered the Patriots' most likely touchdown threats, offering attractive payouts for bettors who believe New England can punch it in against a Bills defense that will be tested by the hostile crowd energy.