49ers-Bucs Betting Promos: Latest Odds, Picks, Offers for NFC Showdown

As the San Francisco 49ers prepare to take on the Tampa Bay Buccaneers at Raymond James Stadium on October 12, 2025, bettors can capitalize on some of the best new user welcome bonuses available. It's a massive matchup with each of these NFC powerhouses trying to push towards a top seed in the conference.

49ers-Bucs Betting Promos: Sportsbook Bonuses for NFL Week 6

This NFC showdown provides a fantastic opportunity to unlock valuable new betting promotions from the industry's top sportsbooks for this Week 6 matchup or any other NFL game on the schedule.

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bet365 Bonus Code TSN365: Claim $200 Bonus for 49ers vs. Buccaneers

bet365 sets itself apart by giving new users the power of choice. With the bonus code TSN365, you can select the welcome offer that best fits your betting style. This unique flexibility makes it one of the most attractive sign-up promotions available for this week's NFL action.

Here are the two fantastic offers you can choose from:

1. Bet $5, Win $200 in Bonus Bets: This is the perfect option for bettors looking for a guaranteed return. Simply sign up with code TSN365, place a wager of just $5 on any market, and you will receive $200 in bonus bets credited to your account, win or lose. It's a low-risk way to instantly build your bankroll.
2. $1,000 First Bet Safety Net: For those looking to make a bigger splash with their first wager, this offer provides a valuable cushion. Place your initial bet, and if it doesn't win, bet365 will refund your stake in the form of bonus bets, up to a maximum of $1,000. This lets you place a confident first bet knowing you have a second chance if things don't go your way.

Details on how to claim this offer, including specific bonus codes, deposit requirements, and first bet actions, are not available from the provided sources.

In addition to the bet365 bonus, NFL bettors can claim a variety of sportsbook bonuses from other top operators like DraftKings, FanDuel, Caesars, and Fanatics.

• The new user DraftKings Sportsbook promo code allows first-timers to bet $5 and get $200 in bonuses (if their bet wins) when they click here
• New users on FanDuel Sportsbook can click here to unlock an offer to bet $5 and get $300 in bonus bets (if they win).
• First-time users can click the link here to activate the Caesars Sportsbook promo code TSN20X which unlocks an offer to bet $1 and get twenty (20) 100% Profit Boost Tokens.
• New Fanatics Sportsbook users can click here to activate the promo code offer to bet $10 and get $100 in FanCash + up to $100 back in FanCash every football gameday.

BetMGM Bonus Code TSN1500: Claim $1,500 First Bet

BetMGM, "The King of Sportsbooks," offers new users a high-value welcome bonus, with the specific promotion varying by state. This ensures that no matter where you are, you can start your BetMGM experience with a significant advantage.

• $1,500 First Bet: For new players in most states, the bonus code TSN1500 unlocks a massive First Bet offer. Place your initial wager, and if it loses, BetMGM will refund your stake in the form of bonus bets, up to a maximum of $1,500. This provides an incredible safety net, allowing you to make a bold first play with peace of mind.
• Bet $10, Get $150 Bonus With a Win: If you are signing up from Michigan, New Jersey, Pennsylvania, or West Virginia, use the bonus code TSN150. With this promotion, you can place a $10 wager on any game. If your bet is a winner, you will receive $150 in bonuses credited to your account.

To claim your offer, sign up for a new BetMGM account and enter the appropriate bonus code for your state during registration.

49ers vs. Buccaneers Betting Preview

A compelling conference game is on the docket for Week 6 as the 49ers head to Florida to face the Buccaneers. The action is scheduled to kick off at 4:25 pm ET from Raymond James Stadium in Tampa. This matchup pits two teams with different offensive strengths, with Tampa Bay currently averaging 26.2 points per game compared to San Francisco's 20.8.

49ers vs. Buccaneers Betting Odds

Odds as of October 9 from MGM.

Fearless Forecast: The Buccaneers open as (-154) moneyline favorites, giving them an implied probability of 60.6% to win the game. The 49ers, despite having won their last four matchups against Tampa Bay, are priced as (+140) underdogs.

The spread sits at a key number of 3 points, a line that presents a fascinating clash of trends. The 49ers have been a covering machine on the road, going 3-0 against the spread (ATS) away from home this season. Conversely, Tampa Bay has struggled to cover at Raymond James Stadium, posting an 0-4 ATS record in their last four home games. However, a significant trend works against San Francisco: they are 0-6 ATS in their last six games as an underdog by fewer than 7 points.

The game total is set at 47.5 points, with compelling data supporting both sides. The Over has been a strong trend for both teams recently, hitting in four of the 49ers' last five road games and four of the Buccaneers' last five home games. Adding to that, the Over has cashed in seven of Tampa Bay's last eight contests against teams with a winning record. Yet, when these two franchises meet, the games tend to be lower-scoring, with the Under hitting in four of their last five head-to-head matchups.

Narrative: We're looking at a potential trap game for the Buccaneers, who are coming off a statement road win that has the fanbase buzzing. The 49ers arrive as desperate road warriors, having mastered the art of making opposing stadiums feel like home. San Francisco's road confidence figures to kick in against a Tampa Bay squad that's struggled to cover at Raymond James Stadium.

Pick: San Francisco 49ers +3 (-110)

49ers vs. Buccaneers Anytime Touchdown Scorer Props

The anytime touchdown scorer market offers exciting wagering opportunities on which players will find the end zone in this matchup. Unsurprisingly, 49ers running back Christian McCaffrey leads all players as a heavy favorite at (-170) to score, a testament to his central role in San Francisco's offense.

For the favored Buccaneers, lead running back Rachaad White also has short odds at (-145) to punch one in. Tampa Bay's passing attack provides intriguing value, with wideouts Emeka Egbuka (+123) and Chris Godwin (+178) listed as prominent scoring threats. For those looking for a potential value play on the 49ers side, tight end Jake Tonges is priced at (+280) to score a touchdown.

Lock of the Week: Christian McCaffrey anytime TD (-170). The 49ers' offensive centerpiece will be up for the duel in a revenge-minded spot, and Tampa Bay's run defense figures to get tested early and often by San Francisco's ground attack.