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Seahawks vs. Cardinals live score, updates, highlights from NFL 'Thursday Night Football' game

Jake Mozarsky

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Seahawks vs. Cardinals live score, updates, highlights from NFL 'Thursday Night Football' game image

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NFL Week 4 kicks off with a divisional showdown in the desert between two 2-1 teams.

The Seattle Seahawks and Arizona Cardinals have both gotten off to strong starts in the 2025 season, and their clash on Thursday Night Football has major implications for the NFC West. While it’s early in the season, this game will be a crucial step in their playoff aspirations, especially since both of their lone losses have come at the hands of a division rival in the San Francisco 49ers.

The Seahawks have a revamped offense in year two of the Mike Macdonald era. Seattle has a new quarterback at the helm in 2025 in Sam Darnold, who threw for a career-high 4,319 yards and 35 touchdowns in 2024 with the Minnesota Vikings. Along with Darnold, Seattle traded for former triple-crown winner Cooper Kupp to pair alongside star wideout Jaxson Smith-Njigba, who has over 96 yards in all three games this season.

On the other side, Arizona opened the season with two straight wins over the New Orleans Saints and Carolina Panthers before losing to San Francisco in Week 3. The Cardinals' offense suffered a major blow when James Conner sustained an ankle injury that will sideline him for the remainder of the season, but there are still plenty of offensive pieces at quarterback Kyler Murray's disposal, including Trey McBride and Marvin Harrison Jr. 

Both teams will look to grab their first NFC West win of the season on Thursday night and advance to 3-1. Follow along for updates throughout the game below.

STREAM: Watch Seahawks vs. Cardinals live with Amazon Prime

Seahawks vs. Cardinals score

 

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Seahawks vs. Cardinals live updates, highlights from 'Thursday Night Football'

8:10 p.m.: Seattle and Arizona legends will be behind the camera lense for tonight's game.

Seahawks running back Marshawn Lynch and Diamondbacks pitcher Randy Johnson will be photographers in Arizona.

8:00 p.m.: The Seahawks are getting key pieces in their secondary for tonight's game. This includes Devon Witherspoon, who missed the past two games with an ankle injury.

Safety Julian Love is also returning for Seattle.

7:40 p.m.: The Cardinals have also taken the field in their rivalry edition uniforms.

7:35 p.m.: Sam Darnold and the Seahawks have taken the field.

Darnold has two touchdown passes in each of his past two games. Through three games, he has 663 yards, four touchdowns and two interceptions.

7:10 p.m.: Players have started to take the field for warmups. This includes Cardinals' signal-caller Kyler Murray and wide receiver Marvin Harrison Jr., who are both dressed to match the Arizona sand theme.

Harrison Jr. has not had a great start to the 2025 season, capped off with a big drop in Week 3 against the San Francisco 49ers. He hopes to bounce back tonight.

6:53 p.m.: Seattle has also announced its inactives for the Week 4 matchup against Arizona.

Zach Charbonnet, who was questionable throughout the week with a foot injury, is officially active. 

6:50 p.m.: The Cardinals have officially posted their inactives for Thursday Night Football.

Most notable is Will Johnson, who Arizona selected in the second round of the 2025 NFL Draft, who is out with a groin injury. 

6:42 p.m.: Expect celebrities in the house for a primetime matchup, and that includes Peter Herbstreit.

Peter, who accompanies Kirk on his broadcasting trips, has taken the field in Arizona.

Herbstreit is a color analyst for tonight's game, then will be traveling to Happy Valley, Pa. for ESPN's "College GameDay" on Saturday morning. Right after, he'll be going down to Athens, Ga. for a primetime kickoff between No. 17 Alabama and No. 5 Georgia. Kirk and Peter will travel over 4,200 miles.

6:41 p.m.: We're only a few hours away from kickoff, and State Farm Stadium looks different.

As part of the NFL's "rivalry uniforms" release, the Cardinals will be wearing their sand-colored uniforms. So, the field in Glendale had to match.

On the other side, Seattle will be wearing its traditional navy blue jerseys with "wolf grey" pants.

MORE SEAHAWKS-CARDINALS NEWS:

Where to watch Seahawks vs. Cardinals

Seahawks vs. Cardinals start time 

  • Date: September 26
  • Time: 8:15 p.m. ET

This is both teams' first primetime game of the season. It will kickoff at 8:15 p.m. ET from State Farm Stadium in Glendale, Ariz.

What channel is Seahawks vs. Cardinals on?

Seahawks vs Cardinals will be Week 4's edition of "Thursday Night Football," on Amazon Prime Video. Al Michaels and Kirk Herbstreit are on the call. Kaylee Hartung will be on the sidelines.

Fans in Phoenix can watch the game on Fox, while those in the Seattle area can also tune in on Seahawks.com and the Seahawks app.

Seahawks schedule 2025

WeekDateMatchupTimeTV/Result
19/7vs 49ers4:25 p.m. ET49ers 17, Seahawks 13
29/14at Steelers1:00 p.m. ETSeahawks 31, Steelers 17
39/21vs Saints4:05 p.m. ETSeahawks 44, Saints 13
49/25at Cardinals8:15 p.m. ETAmazon Prime Video
510/5vs Buccaneers4:05 p.m. ETCBS
610/12at Jaguars1:00 p.m. ETFox
710/20vs Texans10:00 p.m. ETESPN
8BYE---
911/2at Commanders8:20 p.m. ETNBC
1011/9vs Cardinals 4:05 p.m. ETCBS
1111/16at Rams4:05 p.m. ETFox
1211/23at Titans1:00 p.m. ETFox
1311/30vs Vikings4:05 p.m. ETFox
1412/7at Falcons1:00 p.m. ETFox
1512/14vs Colts4:25 p.m. ETCBS
1612/18vs Rams8:15 p.m. ETAmazon Prime Video
17TBDat PanthersTBDTBD
18TBDat 49ersTBDTBD

Cardinals schedule 2025

WeekDateMatchupTimeTV/Result
19/7at Saints1:00 p.m. ETCardinals 20, Saints 13
29/14vs Panthers4:05 p.m. ETCardinals 27, Panthers 22
39/21at 49ers4:25 p.m. ET49ers 16, Cardinals 15
49/25vs Seahawks8:15 p.m. ETAmazon Prime Video
510/5vs Titans4:05 p.m. ETCBS
610/12at Colts1:00 p.m. ETFox
710/19vs Packers4:25 p.m. ETFox
8BYE---
911/3at Cowboys8:15 p.m. ETABC / ESPN
1011/9at Seahawks4:05 p.m. ETCBS
1111/16vs 49ers4:05 p.m. ETFox
1211/23vs Jaguars4:05 p.m. ETCBS
1311/30at Buccaneers1:00 p.m. ETFox
1412/7vs Rams4:25 p.m. ETFox
1512/14at Texans1:00 p.m. ETFox
1612/21vs Falcons4:05 p.m. ETFox
17TBDat BengalsTBDTBD
18TBDat RamsTBDTBD

Jake Mozarsky

Jake Mozarsky joined The Sporting News as an Editorial Intern in August 2025 after earning both his bachelor’s and master’s degrees from Northwestern University. He has previously written for Marquee Sports Network, Chicago This Week, Inside NU and The Daily Northwestern.